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Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey, Panda (100%); Gorilla, Dog, Elephant, Horse (93%); Mouse, Rat, Hamster (86%).
For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation (Kim et al., 2006 ).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Acylsphingosine kinase; Ceramide kinase; CERK antibody; hCERK; Lipid kinase 4; lipid kinase LK4; LK4
Gene Aliases: CERK; dA59H18.2; dA59H18.3; hCERK; KIAA1646; LK4
UniProt ID: (Human) Q8TCT0
Entrez Gene ID: (Human) 64781
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