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Invitrogen
CERKL Polyclonal Antibody
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Application
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CERKL Antibody (PA5-112948) in ICC/IF
Immunocytochemichal analysis of CERKL in MCF-7 cells using a Polyclonal antibody (Product # PA5-112948) at a dilution of 1:100. An Alexa Fluor 488-congugated Goat Anti-Rabbit IgG(H+L) secondary antibdoy was used.
Product Details
PA5-112948
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Ceramide kinase-like protein (1-558AA)
Conjugate
Unconjugated
Form
Liquid
Concentration
3.5 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2867682
Target Information
This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.[provided by RefSeq, May 2010].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ceramide kinase-like; Ceramide kinase-like protein; retinitis pigmentosa 26 (autosomal recessive)
Gene Aliases: CERKL; Gm1958; RP26
UniProt ID: (Human) Q49MI3
Entrez Gene ID: (Human) 375298, (Mouse) 228094
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