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Proteintech

CFHR3 Polyclonal Antibody

7 References

View all (5) CFHR3 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (7)

Application

CFHR3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 7

CFHR3 Antibody (16583-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded human liver tissue slide using (Product # 16583-1-AP) (CFHR3 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

CFHR3 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

16583-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:3,000

View 5 publications 5 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CFHR3 Fusion Protein Ag9963 (1-330 aa encoded by BC058009)

View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

0.28 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MLLLINVIL TLWVSCANGQ VKPCDFPDIK HGGLFHENMR RPYFPVAVGK YYSYYCDEHF ETPSGSYWDY IHCTQNGWSP AVPCLRKCYF PYLENGYNQN YGRKFVQGNS TEVACHPGYG LPKAQTTVTC TEKGWSPTPR CIRVRTCSKS DIEIENGFIS ESSSIYILNK EIQYKCKPGY ATADGNSSGS ITCLQNGWSA QPICINSSEK CGPPPPISNG DTTSFLLKVY VPQSRVEYQC QPYYELQGSN YVTCSNGEWS EPPRCIHPCI ITEENMNKNN IKLKGRSDRK YYAKTGDTIE FMCKLGYNAN TSILSFQAVC REGIVEYPRC E (1-330 aa encoded by BC058009)

Target Information

The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

A novel hypoxia-driven gene signature that can predict the prognosis of hepatocellular carcinoma.

Bioengineered

Zeng Z,Lei S,Wang J,Yang Y,Lan J,Tian Q,Chen T,Hao X

Sun May 01 00:00:00 UTC 2022

A novel hypoxia-driven gene signature that can predict the prognosis of hepatocellular carcinoma.

Bioengineered

Zeng Z,Lei S,Wang J,Yang Y,Lan J,Tian Q,Chen T,Hao X

Sun May 01 00:00:00 UTC 2022

Complement factor H‑related 3 overexpression affects hepatocellular carcinoma proliferation and apoptosis.

Molecular medicine reports

Liu H,Zhang L,Wang P

Sun Sep 01 00:00:00 UTC 2019

Quantitative analysis of hydroxyapatite-binding plasma proteins in genotyped individuals with late-stage age-related macular degeneration.

Experimental eye research

Arya S,Emri E,Synowsky SA,Shirran SL,Barzegar-Befroei N,Peto T,Botting CH,Lengyel I,Stewart AJ

Sun Jul 01 00:00:00 UTC 2018

Quantitative analysis of hydroxyapatite-binding plasma proteins in genotyped individuals with late-stage age-related macular degeneration.

Experimental eye research

Arya S,Emri E,Synowsky SA,Shirran SL,Barzegar-Befroei N,Peto T,Botting CH,Lengyel I,Stewart AJ

Sun Jul 01 00:00:00 UTC 2018

Complement-Regulatory Proteins CFHR1 and CFHR3 and Patient Response to Anti-CD20 Monoclonal Antibody Therapy.

Clinical cancer research : an official journal of the American Association for Cancer Research

Rogers LM,Mott SL,Smith BJ,Link BK,Sahin D,Weiner GJ

Wed Feb 15 00:00:00 UTC 2017

Complement-Regulatory Proteins CFHR1 and CFHR3 and Patient Response to Anti-CD20 Monoclonal Antibody Therapy.

Clinical cancer research : an official journal of the American Association for Cancer Research

Rogers LM,Mott SL,Smith BJ,Link BK,Sahin D,Weiner GJ

Wed Feb 15 00:00:00 UTC 2017

A haplotype in CFH family genes confers high risk of rare glomerular nephropathies.

Scientific reports

Ding Y,Zhao W,Zhang T,Qiang H,Lu J,Su X,Wen S,Xu F,Zhang M,Zhang H,Zeng C,Liu Z,Chen H

Thu Jul 20 00:00:00 UTC 2017

A haplotype in CFH family genes confers high risk of rare glomerular nephropathies.

Scientific reports

Ding Y,Zhao W,Zhang T,Qiang H,Lu J,Su X,Wen S,Xu F,Zhang M,Zhang H,Zeng C,Liu Z,Chen H

Thu Jul 20 00:00:00 UTC 2017

A novel quantitative hemolytic assay coupled with restriction fragment length polymorphisms analysis enabled early diagnosis of atypical hemolytic uremic syndrome and identified unique predisposing mutations in Japan.

PloS one

Yoshida Y,Miyata T,Matsumoto M,Shirotani-Ikejima H,Uchida Y,Ohyama Y,Kokubo T,Fujimura Y

Mon Feb 29 00:00:00 UTC 2016

PloS one

Yoshida Y,Miyata T,Matsumoto M,Shirotani-Ikejima H,Uchida Y,Ohyama Y,Kokubo T,Fujimura Y

Mon Feb 29 00:00:00 UTC 2016

Bioinformatics

Protein Aliases: complement factor H-related 3; Complement factor H-related protein 3; DOWN16; FHR-3; H factor-like 4; H factor-like protein 3

Gene Aliases: CFHL3; CFHR3; DOWN16; EG624286; FHR-3; FHR3; HLF4

UniProt ID: (Human) Q02985

Entrez Gene ID: (Human) 10878, (Mouse) 624286

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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CFHR3 Polyclonal Antibody

CFHR3 Antibody (16583-1-AP) in IHC (P)

Product Details

16583-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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