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Recommended positive controls: Jurkat, Raji, K562.
Predicted reactivity: Mouse (91%), Bovine (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATP-dependent helicase CHD4; CHD-4; Chromodomain-helicase-DNA-binding protein 4; Mi-2 autoantigen 218 kDa protein; Mi2-beta; MI2B
Gene Aliases: CHD-4; CHD4; Mi-2b; Mi2-BETA
UniProt ID: (Human) Q14839
Entrez Gene ID: (Human) 1108
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