Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Sequence of this protein is as follows: GMTNHQLSTT EWNDETLYQE FNGLKKMNPK LKTLLAIGGW NFGTQKFTDM VATANNRQTF VNSAIRFLRK YSFDGLDLDW EYPGSQGSPA VDKERFTTLV QDLANAFQQE
Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: chitinase 1 (chitotriosidase); Chitinase-1; Chitotriosidase; Chitotriosidase-1; EC 3.2.1.14; FLJ00314; MGC125322; plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase
Gene Aliases: CHI3; CHIT; CHIT1; CHITD
UniProt ID: (Human) Q13231
Entrez Gene ID: (Human) 1118
Molecular Function:
glycosidase
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