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PA1-23544 detects Muscarinic Acetylcholine Receptor M4 in Human samples.
Muscarinic acetylcholine receptor M4 is an Acetylcholine Receptor. Unlike muscarinic receptor M2, the M4 receptor is not involved in smooth muscle contraction. The clinical relevance of this receptor is unknown. However, mouse studies have linked it to adenylyl cyclase inhibition. Muscarinic acetylcholine receptor M4 has been reported to be expressed in many regions of the rat brain, particularly the striatum and hippocampus. ESTs have been isolated from human breast and eye libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: acetylcholine receptor; acetylcholine receptor, muscarinic 4; cholinergic receptor; cholinergic receptor, muscarinic 4; Muscarinic acetylcholine receptor M4
Gene Aliases: CHRM4; HM4; M4R
UniProt ID: (Human) P08173
Entrez Gene ID: (Human) 1132
Molecular Function:
G-protein coupled receptor
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