Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Immunogen sequence: EEAKRPPPRA PGDPLSSPSP TALPQGGSHT ETEDRLFKHL FRGYNRWARP VPNTSDVVIV RFGLSIAQLI DVDEKNQMMT TNVWLKQEWS DYKLRWNPTD FGNITSLRVP SEMIWIPDIV LYNNADGEFA VTHMTKAHLF STGTVHWVPP AIYKSSCSID VTFFPFDQQN CKMKFGSWTY DKAKIDLEQM EQTVDLKDYW ESGEWAIVNA TGTYNSKKYD CCAEIYPDVT YAFVIRRL
After binding acetylcholine, the ACHR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: acetylcholine receptor; cholinergic receptor; cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal); Neuronal acetylcholine receptor subunit alpha-2; nicotinic acetylcholine receptor
Gene Aliases: ACHR; Acra2; Chrna2
UniProt ID: (Rat) P12389
Entrez Gene ID: (Rat) 170945
Molecular Function:
ligand-gated ion channel
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