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CHST15 Antibody (14298-1-AP) in WB
Various lysates were subjected to SDS PAGE followed by western blot with (Product # 14298-1-AP) CHST15 antibody at dilution of 1:2,000 incubated at room temperature for 1.5 hours.
产品信息
14298-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CHST15 Fusion Protein Ag5679 (103-451 aa encoded by BC050540)
偶联物
Unconjugated
形式
Liquid
浓度
0.23 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: QELLISSPF HYGGFPSNPS LMDSENPSDT KEHHHQSSVN NISYMKDYPS IKLIINSITT RIEFTTRQLP DLEDLKKQEL HMFSVIPNKF LPNSKSPCWY EEFSGQNTTD PYLTNSYVLY SKRFRSTFDA LRKAFWGHLA HAHGKHFRLR CLPHFYIIGQ PKCGTTDLYD RLRLHPEVKF SAIKEPHWWT RKRFGIVRLR DGLRDRYPVE DYLDLFDLAA HQIHQGLQAS SAKEQSKMNT IIIGEASAST MWDNNAWTFF YDNSTDGEPP FLTQDFIHAF QPNARLIVML RDPVERLYSD YLYFASSNKS ADDFHEKVTE ALQLFENCML DYSLRACVYN NTLNNAMPVC (103-451 aa encoded by BC050540)
靶标信息
GALNAC4S-6ST is a sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc(4, 6-SO(4)) repeating units. It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc(4SO4)-GlcA(2SO4)-GalNAc(6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate. GALNAC4S-6ST may also act as a B-cell receptor involved in BCR ligation-mediated early activation that mediate regulatory signals key to B-cell development and/or regulation of B-cell-specific RAG expression; however such results are unclear in vivo.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: B cell RAG associated protein; B cell RAG associated protein (GALNAC4S-6ST); B-cell RAG-associated gene protein; Carbohydrate sulfotransferase 15; DKFZp781H1369; GalNAc 4-sulfate 6-O-sulfotransferase; GalNAc4S-6ST; hBRAG; MGC34346; N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase; RP11-47G11.1
基因别名: 4631426J05Rik; BRAG; CHST15; GALNAC4S-6ST; GALNAC4S6ST; GalNAcS-6ST; KIAA0598; MAd5; mKIAA0598
UniProt ID: (Human) Q7LFX5, (Rat) Q8CHI9, (Mouse) Q91XQ5
Entrez Gene ID: (Human) 51363, (Rat) 286974, (Mouse) 77590
