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Invitrogen

CK1 delta Polyclonal Antibody

2 References

View all (10) CK1 delta antibodies

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Catalog # PA5-32129

Price (KRW)

596,000

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Ends: 30-Jun-2025

701,000

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100 µL

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Datasheet

Protocols

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Antibody Testing Data (4)

Application

CK1 delta Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 4

CK1 delta Antibody (PA5-32129) in ICC/IF

Immunocytochemistry (Confocal immunofluorescence) of CK1 delta in paraformaldehyde-fixed HeLa. Samples were incubated with CK1 delta polyclonal antibody (Product # PA5-32129) using a dilution of 1:500 (green). Alpha-tubulin filaments were labeled with alpha Tubulin monoclonal antibody (Product # MA1-25054) (Red) at 1:2,000.

CK1 delta Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Product Details

PA5-32129

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:3,000

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:1,000

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

1:100-1:1,000

Product Specifications

Species Reactivity

Human, Mouse

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human Casein Kinase 1 delta. The exact sequence is proprietary.

Conjugate

Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7, with 20% glycerol

Contains

0.025% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2549602

Product Specific Information

Recommended positive controls: HeLa, BCL-1.

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

CSNK1D (CK1 delta), a serine/threonine kinase, plays a critical role in Wnt/beta-catenin signaling pathway. This pathway is important in both development and cancer. The encoded protein may also be involved in the regulation of apoptosis, circadian rhythm, microtubule dynamics, chromosome segregation, and p53-mediated effects on growth. The encoded protein is highly similar to the mouse and rat CK1 delta homologs. Three transcript variants encoding different isoforms have been found for CK1 delta.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Structurally and Morphologically Distinct Pathological Tau Assemblies Differentially Affect GVB Accumulation.

International journal of molecular sciences

Jorge-Oliva M,van Weering JRT,Scheper W

PA5-32129 was used in Western Blotting to indicate that tau aggregate structure and/or subcellular localization may be key determinants of GVB accumulation.

Thu Jun 29 00:00:00 UTC 2023

The unfolded protein response is activated in the olfactory system in Alzheimer's disease.

Acta neuropathologica communications

Murray HC,Dieriks BV,Swanson MEV,Anekal PV,Turner C,Faull RLM,Belluscio L,Koretsky A,Curtis MA

PA5-32129 was used in Immunohistochemistry on paraffin embedded tissues-immunofluorescence to investigate regulatory mechanisms governing the unfolded protein response in the context of Alzheimer's disease.

Tue Jul 14 00:00:00 UTC 2020

Bioinformatics

Protein Aliases: casein kinase 1; casein kinase 1, delta; Casein kinase I isoform delta; CK1d; CK1delta; CKI-delta; CKId; HGNC:2452; Tau-protein kinase CSNK1D

Gene Aliases: 1200006A05Rik; AA409348; ASPS; CKIdelta; CSNK1D; D930010H05Rik; FASPS2; HCKID

UniProt ID: (Human) P48730, (Mouse) Q9DC28

Entrez Gene ID: (Human) 1453, (Mouse) 104318

Function(s)

glycoprotein binding protein kinase activity protein serine/threonine kinase activity protein binding ATP binding peptide binding tau-protein kinase activity phosphoprotein binding cadherin binding involved in cell-cell adhesion nucleotide binding kinase activity transferase activity transferase activity, transferring phosphorus-containing groups non-receptor serine/threonine protein kinase

Process(es)

G2/M transition of mitotic cell cycle positive regulation of protein phosphorylation DNA repair rRNA processing protein phosphorylation endocytosis microtubule nucleation Golgi organization signal transduction regulation of cell shape Wnt signaling pathway peptidyl-serine phosphorylation positive regulation of proteasomal ubiquitin-dependent protein catabolic process circadian regulation of gene expression protein localization to Golgi apparatus nonmotile primary cilium assembly regulation of circadian rhythm COPII vesicle coating spindle assembly protein localization to cilium protein localization to centrosome positive regulation of canonical Wnt signaling pathway cell-cell adhesion cellular response to nerve growth factor stimulus positive regulation of non-canonical Wnt signaling pathway phosphorylation rhythmic process

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