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CKS1B protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS1B mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects a specialized role for the encoded protein. At least two transcript variants have been identified for this gene, and it appears that only one of them encodes a protein.
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Protein Aliases: CDC2-associated protein CKS1; CDC28 protein kinase 1; CDC28 protein kinase 1B; cell division control protein CKS1; CKS-1; cyclin-dependent kinase regulatory subunit 1; Cyclin-dependent kinases regulatory subunit 1; NB4 apoptosis/differentiation related protein; PNAS-143; Sid 1334
Gene Aliases: 2410005G18Rik; 2610005D03Rik; AA407784; CKS1; CKS1B; ckshs1; PNAS-143; PNAS-16; PNAS-18; Sid1334
UniProt ID: (Human) P61024, (Mouse) P61025
Entrez Gene ID: (Human) 1163, (Mouse) 54124
Molecular Function:
scaffold/adaptor protein
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