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Proteintech
Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. Calpain S1 is a small subunit common to both calpain I and II and is associated with myotonic dystrophy.
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Protein Aliases: 30K; Calcium-activated neutral proteinase small subunit; Calcium-dependent protease small subunit; Calcium-dependent protease small subunit 1; calcium-dependent protease, small subunit; calpain 4; calpain 4, small subunit (30K); Calpain regulatory subunit; Calpain small subunit 1; calpain, small polypeptide; calpain, small subunit 1; CANP small subunit; CDPS; CSS1; small pol
Gene Aliases: CALPAIN4; CANP; CANPS; CAPN4; CAPNS; CAPNS1; CDPS; CSS1
UniProt ID: (Human) P04632, (Rat) Q64537
Entrez Gene ID: (Human) 826, (Rat) 29156
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