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Immunogen sequence: EAKEEFAHKT LAMDVMKPRR NDPLLTVLTQ DSMTVEDVET IISETTYSGF PVVVSRESQR LVGFVLRRDL IISIENARKK QDGVVSTSII YFTEHSPPLP PYTPPTLKLQ NILDLSPFTV TD
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.
Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons. Important for normal acidification of the endosome lumen. May play an important role in renal tubular function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Chloride channel protein 5; chloride channel, voltage-sensitive 5; Chloride transporter ClC-5; ClC-5; H(+)/Cl(-) exchange transporter 5; hClC-K2; voltage-gated chloride ion channel CLCN5
Gene Aliases: ClC-5; CLC5; CLCK2; CLCN5; DENTS; hCIC-K2; NPHL1; NPHL2; XLRH; XRN
UniProt ID: (Human) P51795
Entrez Gene ID: (Human) 1184
Molecular Function:
ion channel
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