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Application
FIGURE: 1 / 1
CLC-7 (CLCN7) Antibody (ACL-008-200UL) in WB
Western blot analysis of mouse kidney (lanes 1 and 3) and rat brain (lanes 2 and 4)lysates: - 1,2. Anti-CLC-7 (CLCN7) Antibody (#ACL-008), (1:200).3,4. Anti-CLC-7 (CLCN7) Antibody , preincubated with CLC-7/CLCN7 Blocking Peptide (#BLP-CL008).
Product Details
ACL-008-200UL
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)KDLARYRLGKGGLE, corresponding to amino acid residues 783-796 of rat CLC-7, Intracellular, C-terminus
Conjugate
Unconjugated
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Chloride channel 7 alpha subunit; Chloride channel protein 7; ClC-7; CLCN-7; H(+)/Cl(-) exchange transporter 7
Gene Aliases: AA409691; AW538136; ClC-7; Clc7; Clcn7; D17Wsu51e
UniProt ID: (Rat) P51799, (Mouse) O70496
Entrez Gene ID: (Rat) 29233, (Mouse) 26373
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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