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FIGURE: 1 / 3
Antibody detects endogenous levels of total CLCA1.
This gene encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although the site at which the precursor is cleaved has not been precisely determined. The encoded protein may be involved in mediating calcium-activated chloride conductance in the intestine.
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Protein Aliases: CaCC-1; Calcium-activated chloride channel family member 1; Calcium-activated chloride channel family member 3; Calcium-activated chloride channel protein 1; Calcium-activated chloride channel regulator 1; calcium-dependent chloride channel-1; chloride channel calcium activated 2; chloride channel calcium activated 3; chloride channel regulator 1; chloride channel, calcium activated, family member 1; CLCA family member 1, chloride channel regulator; hCLCA1; mCLCA3; Protein gob-5
Gene Aliases: CACC; CaCC-1; CACC1; CLCA1; Clca2; Clca3; CLCRG1; gob-5; GOB5; hCaCC-1; hCLCA1
UniProt ID: (Human) A8K7I4, (Mouse) Q9D7Z6
Entrez Gene ID: (Human) 1179, (Mouse) 23844
Molecular Function:
ion channel
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