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CD371 is also known as Clec12A or Myeloid Inhibitory C-type Lectin-like receptor (MICL). CD371 is a highly glycosylated transmembrane receptor with a cytoplasmic ITIM that associates with SHP1 and SHP2. CD371 is expressed mainly on granulocytes, monocytes, macrophages, and dendritic cells, including plasmacytoid dendritic cells. Expression of CD371 on NK cells remains controversial. Although the function of CD371 is not fully understood, studies suggest that this receptor plays a role in inflammation and LPS activation.
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Protein Aliases: C-type lectin domain family 12 member A; C-type lectin domain family 12, member A; C-type lectin protein CLL-1; C-type lectin-like molecule 1; C-type lectin-like molecule-1; CD371; CLL-1; DCAL-2; Dendritic cell-associated lectin 2; hKLRL1; Killer cell C-type lectin-like receptor L1; MICL; Myeloid inhibitory C-type lectin-like receptor
Gene Aliases: CD371; CLEC12A; CLL-1; CLL1; DCAL-2; DCAL2; KLRL1; MICL
UniProt ID: (Human) Q5QGZ9
Entrez Gene ID: (Human) 160364
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