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Invitrogen
CLEC5A Monoclonal Antibody (283834)
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Application
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CLEC5A Antibody (MA5-23909) in Flow
Flow cytometry of CLEC5A in Human peripheral blood granulocytes. Samples were incubated in CLEC5A monoclonal antibody (Product # MA5-23909) or isotype control antibody followed by Phycoerythrin-conjugated Anti-Mouse IgG Secondary Antibody.
Product Details
MA5-23909
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
283834
Immunogen
Mouse myeloma cell line NS0-derived recombinant human MDL-1/CLEC5A Tyr26-Lys188
Conjugate
Unconjugated
Form
Lyophilized
Concentration
0.5 mg/mL
Purification
Protein A/G
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2576925
Product Specific Information
This antibody does not cross-react with recombinant mouse MDL-1.
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
Functions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP. Regulates inflammatory responses. Acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation. Critical macrophage receptor for dengue virus serotypes 1-4. The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 5; C-type lectin domain family 5 member A; C-type lectin domain family 5, member A; C-type lectin superfamily member 5; MDL-1; Myeloid DAP12-associating lectin 1; myeloid DAP12-associating lectin-1
Gene Aliases: CLEC5A; CLECSF5; MDL-1; MDL1
UniProt ID: (Human) Q9NY25
Entrez Gene ID: (Human) 23601
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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