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CLNS1A Antibody (PA5-117874) in WB
Western Blot using CLNS1A Polyclonal Antibody (Product # PA5-117874) at 1:500 dilution. Lane A: Jurkat Whole Cell Lysate, Lane B: HeLa Whole Cell Lysate, Lane C: K562 Whole Cell Lysate, Lane D: HepG2 Whole Cell Lysate. Lysates/proteins at 30 μg per lane. Secondary antibody: Goat Anti-Rabbit IgG (H+L)/HRP at 1:10,000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size: 26 kDa. Observed band size: 38 kDa.
Product Details
PA5-117874
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived Human CLNS1A fragment
Conjugate
Form
Liquid
Purification
Antigen affinity chromatography, Protein A
Storage buffer
PBS, pH 7
Contains
0.03% ProClin 300
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2902482
Target Information
Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility. Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as peroxisome proliferator-activated receptor gamma (PPARG). Acts as coactivator for PPARG and enhances its adipocyte differentiation-inducing activity; the function seems to involve differential recruitment of acetylated and methylated histone H3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ARPC1A; chloride channel regulatory protein; Chloride channel, nucleotide sensitive 1A; chloride channel, nucleotide-sensitive, 1A; Chloride conductance regulatory protein ICln; Chloride ion current inducer protein; ClCI; I(Cln); Methylosome subunit pICln; Reticulocyte pICln; reticulocyte protein ICln; SOP2-like protein; SOP2L
Gene Aliases: CLCI; CLNS1A; CLNS1B; ICLN
UniProt ID: (Human) P54105
Entrez Gene ID: (Human) 1207
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