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Invitrogen

CNPase Monoclonal Antibody (CL2871)

Advanced Verification

2 References

View all (26) CNPase antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (8)
Advanced Verification (2)

Application

CNPase Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 10

CNPase Antibody (MA5-31374) in IHC (P)

Immunohistochemical analysis of CNPase in mouse striatum using CNPase Monoclonal Antibody (CL2871) (Product # MA5-31374) shows strong positivity in oligodendrocytes and myelinated neural fibers.

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Product Details

MA5-31374

Applications

Tested Dilution

Publications

Western Blot (WB)

0.7-1 µg/mL

Immunohistochemistry (Paraffin) (IHC (P))

1:2,500-1:5,000

Flow Cytometry (Flow)

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

CL2871

Immunogen

Recombinant protein corresponding to Human CNP

View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2787011

Product Specific Information

Immunogen sequence: PGVLHCTTKF CDYGKAPGAE EYAQQDVLKK SYSKAFTLTI SALFVTPKTT GARVELSEQQ LQLWPSDVDK LSPTDNLPRG SRAHITL

Target Information

CNP may participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Assessment of neurotransmitter release in human iPSC-derived neuronal/glial cells: a missing in vitro assay for regulatory developmental neurotoxicity testing.

Reproductive toxicology (Elmsford, N.Y.)

Cervetto C,Pistollato F,Amato S,Mendoza-de Gyves E,Bal-Price A,Maura G,Marcoli M

MA5-31374 was used in Flow Cytometry to measure the release of neurotransmitters in a previously characterized human induced pluripotent stem cell (hiPSC)-derived neural stem cells (NSCs) model undergoing differentiation towards neurons and glia.

Sat Apr 01 00:00:00 UTC 2023

SIRT1 regulates sphingolipid metabolism and neural differentiation of mouse embryonic stem cells through c-Myc-SMPDL3B.

eLife

Fan W,Tang S,Fan X,Fang Y,Xu X,Li L,Xu J,Li JL,Wang Z,Li X

MA5-31374 was used in Flow Cytometry to study sphingolipid degradation in mouse embryonic stem cells.

Thu May 27 00:00:00 UTC 2021

Bioinformatics

Protein Aliases: 2', 3' cyclic nucleotide 3' phosphohydrolase; 2',3'-cyclic-nucleotide 3'-phosphodiesterase; CNP; CNPase; cyclic nucleotide phosphodiesterase 1

Gene Aliases: CNP; Cnp-1; CNP1; CNPase; CNPF; CNPI; CNPII

UniProt ID: (Human) P09543, (Mouse) P16330, (Rat) P13233

Entrez Gene ID: (Human) 1267, (Mouse) 12799, (Rat) 25275

Function(s)

RNA binding 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity cyclic nucleotide binding hydrolase activity hydrolase phosphodiesterase metabolite interconversion enzyme

Process(es)

microtubule cytoskeleton organization chemical synaptic transmission axonogenesis aging adult locomotory behavior cyclic nucleotide catabolic process response to toxic substance substantia nigra development forebrain development response to lipopolysaccharide regulation of mitochondrial membrane permeability oligodendrocyte differentiation

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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