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Product Details
67043-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
1E10G6
Immunogen
COMMD5 Fusion Protein Ag18464
Conjugate
Unconjugated
Form
Liquid
Concentration
1000 µg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Aliquoting is unnecessary for -20°C storage.
Target Information
COMMD5 is a protein coding gene. May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis. Down-regulates activation of NF-kappa-B.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: COMM domain-containing protein 5; FLJ13008; HCaRG; hypertension-related calcium regulated; Hypertension-related calcium-regulated gene protein; hypertension-related, calcium regulated
Gene Aliases: COMMD5; HCARG; HT002
UniProt ID: (Human) Q9GZQ3, (Rat) Q9ERR2
Entrez Gene ID: (Human) 28991, (Rat) 245974
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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