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Application
FIGURE: 1 / 1
COPB2 Antibody (PA5-66144) in ICC/IF
Immunofluorescent staining of COPB2 in human cell line U-2 OS shows localization to cytosol. Samples were probed using a COPB2 Polyclonal Antibody (Product # PA5-66144).
Product Details
PA5-66144
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human COPB2. Recombinant protein control fragment (Product #RP-106826).
Conjugate
Unconjugated
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2662814
Product Specific Information
Immunogen sequence: GNANMVNKLAE GAERDGKNNV AFMSYFLQGK VDACLELLIR TGRLPEAAFL ARTYLPSQVS RVVKLWRENL SKVNQKAAE
Highest antigen sequence identity to the following orthologs - mouse 98%, rat 26%.
Target Information
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Beta'-coat protein; Beta'-COP; betaprime-COP; coatomer binding complex, beta prime subunit; coatomer protein complex subunit beta 2 (beta prime); coatomer protein complex subunit beta prime; coatomer protein complex, subunit beta 2 (beta prime); Coatomer subunit beta'; p102
Gene Aliases: beta'-COP; COPB2
UniProt ID: (Human) P35606
Entrez Gene ID: (Human) 9276
Performance Guarantee
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