Loading ...

Proteintech

COQ9 Polyclonal Antibody

6 References

View all (8) COQ9 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (11)

Application

COQ9 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 11

COQ9 Antibody (14874-1-AP) in ICC/IF

Immunofluorescent analysis of (-20&(8)451; Ethanol) fixed HepG2 cells using (Product # 14874-1-AP) (COQ9 antibody) at dilution of 1:100 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L).

COQ9 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

COQ9 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

14874-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2400

View 4 publications 4 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:10-1:100

View 2 publications 2 publications

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

COQ9 Fusion Protein Ag6645 (1-318 aa encoded by BC064946)

View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

0.25 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MAAAAVSGA LGRAGWRLLQ LRCLPVARCR QALVPRAFHA SAVGLRSSDE QKQQPPNSFS QQHSETQGAE KPDPESSHSP PRYTDQGGEE EEDYESEEQL QHRILTAALE FVPAHGWTAE AIAEGAQSLG LSSAAASMFG KDGSELILHF VTQCNTRLTR VLEEEQKLVQ LGQAEKRKTD QFLRDAVETR LRMLIPYIEH WPRALSILML PHNIPSSLSL LTSMVDDMWH YAGDQSTDFN WYTRRAMLAA IYNTTELVMM QDSSPDFEDT WRFLENRVND AMNMGHTAKQ VKSTGEALVQ GLMGAAVTLK NLTGLNQRR (1-318 aa encoded by BC064946 )

Target Information

Coenzyme Q10 (CoQ10), or ubiquinone, is a mobile lipophilic electron carrier critical for electron transfer by the mitochondrial inner membrane respiratory chain. COQ9 is 1 of several enzymes involved in biosynthesis of CoQ10 and likely functions in modification of the benzoquinone ring.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Human COQ4 deficiency: delineating the clinical, metabolic and neuroimaging phenotypes.

Journal of medical genetics

Laugwitz L,Seibt A,Herebian D,Peralta S,Kienzle I,Buchert R,Falb R,Gauck D,Müller A,Grimmel M,Beck-Woedel S,Kern J,Daliri K,Katibeh P,Danhauser K,Leiz S,Alesi V,Baertling F,Vasco G,Steinfeld R,Wagner M,Caglayan AO,Gumus H,Burmeister M,Mayatepek E,Martinelli D,Tamhankar PM,Tamhankar V,Joset P,Steindl K,Rauch A,Bonnen PE,Froukh T,Groeschel S,Krägeloh-Mann I,Haack TB,Distelmaier F

Thu Sep 01 00:00:00 UTC 2022

ADCK4 Deficiency Destabilizes the Coenzyme Q Complex, Which Is Rescued by 2,4-Dihydroxybenzoic Acid Treatment.

Journal of the American Society of Nephrology : JASN

Widmeier E,Yu S,Nag A,Chung YW,Nakayama M,Fernández-Del-Río L,Hugo H,Schapiro D,Buerger F,Choi WI,Helmstädter M,Kim JW,Ryu JH,Lee MG,Clarke CF,Hildebrandt F,Gee HY

Mon Jun 01 00:00:00 UTC 2020

Coenzyme Q biosynthetic proteins assemble in a substrate-dependent manner into domains at ER-mitochondria contacts.

The Journal of cell biology

Subramanian K,Jochem A,Le Vasseur M,Lewis S,Paulson BR,Reddy TR,Russell JD,Coon JJ,Pagliarini DJ,Nunnari J

Mon Apr 01 00:00:00 UTC 2019

Detection of 6-demethoxyubiquinone in CoQ₁₀ deficiency disorders: Insights into enzyme interactions and identification of potential therapeutics.

Molecular genetics and metabolism

Herebian D,Seibt A,Smits SHJ,Bünning G,Freyer C,Prokisch H,Karall D,Wredenberg A,Wedell A,López LC,Mayatepek E,Distelmaier F

Sat Jul 01 00:00:00 UTC 2017

Detection of 6-demethoxyubiquinone in CoQ₁₀ deficiency disorders: Insights into enzyme interactions and identification of potential therapeutics.

Molecular genetics and metabolism

Herebian D,Seibt A,Smits SHJ,Bünning G,Freyer C,Prokisch H,Karall D,Wredenberg A,Wedell A,López LC,Mayatepek E,Distelmaier F

Sat Jul 01 00:00:00 UTC 2017

Human COQ9 Rescues a coq9 Yeast Mutant by Enhancing Coenzyme Q Biosynthesis from 4-Hydroxybenzoic Acid and Stabilizing the CoQ-Synthome.

Frontiers in physiology

He CH,Black DS,Allan CM,Meunier B,Rahman S,Clarke CF

Sat Jan 29 00:00:00 UTC 2022

Human COQ9 Rescues a coq9 Yeast Mutant by Enhancing Coenzyme Q Biosynthesis from 4-Hydroxybenzoic Acid and Stabilizing the CoQ-Synthome.

Frontiers in physiology

He CH,Black DS,Allan CM,Meunier B,Rahman S,Clarke CF

Sat Jan 29 00:00:00 UTC 2022

COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness.

The Journal of clinical investigation

Heeringa SF,Chernin G,Chaki M,Zhou W,Sloan AJ,Ji Z,Xie LX,Salviati L,Hurd TW,Vega-Warner V,Killen PD,Raphael Y,Ashraf S,Ovunc B,Schoeb DS,McLaughlin HM,Airik R,Vlangos CN,Gbadegesin R,Hinkes B,Saisawat P,Trevisson E,Doimo M,Casarin A,Pertegato V,Giorgi G,Prokisch H,Rötig A,Nürnberg G,Becker C,Wang S,Ozaltin F,Topaloglu R,Bakkaloglu A,Bakkaloglu SA,Müller D,Beissert A,Mir S,Berdeli A,Varpizen S,Zenker M,Matejas V,Santos-Ocaña C,Navas P,Kusakabe T,Kispert A,Akman S,Soliman NA,Krick S,Mundel P,Reiser J,Nürnberg P,Clarke CF,Wiggins RC,Faul C,Hildebrandt F

Sun May 01 00:00:00 UTC 2011

COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness.

The Journal of clinical investigation

Sun May 01 00:00:00 UTC 2011

Bioinformatics

Protein Aliases: coenzyme Q9 homolog; Ubiquinone biosynthesis protein COQ9, mitochondrial

Gene Aliases: 2310005O14Rik; C16orf49; C78387; COQ10D5; COQ9; HSPC326; PSEC0129

UniProt ID: (Human) O75208, (Mouse) Q8K1Z0, (Rat) Q68FT1

Entrez Gene ID: (Human) 57017, (Mouse) 67914, (Rat) 498909

Function(s)

Process(es)

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

COQ9 Polyclonal Antibody

COQ9 Antibody (14874-1-AP) in ICC/IF

Product Details

14874-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Function(s)

Process(es)

Performance Guarantee

We're here to help

Your items have has been added!