Product References
Cyasterone inhibits IL-1β-mediated apoptosis and inflammation via the NF-κB and MAPK signaling pathways in rat chondrocytes and ameliorates osteoarthritisin vivo.
Chinese journal of natural medicines
Teng L,Shen Y,Qu Y,Yang L,Yang Y,Jian X,Fan S,Zhang L,Fu Q
Wed Feb 01 00:00:00 UTC 2023
Cardamonin alleviates chondrocytes inflammation and cartilage degradation of osteoarthritis by inhibiting ferroptosis via p53 pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Gong Z,Wang Y,Li L,Li X,Qiu B,Hu Y
Sat Apr 01 00:00:00 UTC 2023
PET117 assembly factor stabilizes translation activator TACO1 thereby upregulates mitochondria-encoded cytochrome C oxidase 1 synthesis.
Free radical biology & medicine
Sun Q,Shi L,Li S,Li J,Zhang R,Huang X,Shao Y,Feng Z,Peng Y,Yang Z,Liu J,Liu H,Long J
Sun Aug 20 00:00:00 UTC 2023
Isobavachalcone ameliorates the progression of osteoarthritis by suppressing NF-κB signaling pathway.
International immunopharmacology
Guo Q,Zhang M,Dong Y,Liu K,Wang D,Zheng J
Thu Jun 01 00:00:00 UTC 2023
Hypoxia-Inducible Factor-1α Protects Against Intervertebral Disc Degeneration Through Antagonizing Mitochondrial Oxidative Stress.
Inflammation
Yang W,Jia C,Liu L,Fu Y,Wu Y,Liu Z,Yu R,Ma X,Gong A,Liu F,Xia Y,Hou Y,Li Y,Zhang L
Wed Feb 01 00:00:00 UTC 2023
Hypoxia-Inducible Factor-1α Protects Against Intervertebral Disc Degeneration Through Antagonizing Mitochondrial Oxidative Stress.
Inflammation
Yang W,Jia C,Liu L,Fu Y,Wu Y,Liu Z,Yu R,Ma X,Gong A,Liu F,Xia Y,Hou Y,Li Y,Zhang L
Wed Feb 01 00:00:00 UTC 2023
EPC-exosomal miR-26a-5p improves airway remodeling in COPD by inhibiting ferroptosis of bronchial epithelial cells via PTGS2/PGE2 signaling pathway.
Scientific reports
Liu C,Lu J,Yuan T,Xie L,Zhang L
Fri Apr 14 00:00:00 UTC 2023
M2 Macrophage Membrane-Mediated Biomimetic-Nanoparticle Carrying COX-siRNA Targeted Delivery for Prevention of Tendon Adhesions by Inhibiting Inflammation.
Small (Weinheim an der Bergstrasse, Germany)
Sun J,Ju F,Jin J,Wang HL,Li ZJ,Sun YC,Chen QZ,Yang QQ,Tan J,Zhou YL
Tue Aug 01 00:00:00 UTC 2023
Integrating UPLC-Q-Exactive Orbitrap/MS, network pharmacology and experimental validation to reveal the potential mechanism of Tibetan medicine Rhodiola granules in improving myocardial ischemia-reperfusion injury.
Journal of ethnopharmacology
Xing N,Qin J,Ren D,Du Q,Li Y,Mi J,Zhang F,Ai L,Zhang S,Zhang Y,Wang S
Thu Oct 05 00:00:00 UTC 2023
Huc-MSCs-derived exosomes attenuate neuropathic pain by inhibiting activation of the TLR2/MyD88/NF-κB signaling pathway in the spinal microglia by targeting Rsad2.
International immunopharmacology
Gao X,Gao LF,Zhang YN,Kong XQ,Jia S,Meng CY
Sun Jan 01 00:00:00 UTC 2023
Silibinin alleviates ferroptosis of rat islet β cell INS-1 induced by the treatment with palmitic acid and high glucose through enhancing PINK1/parkin-mediated mitophagy.
Archives of biochemistry and biophysics
Du Q,Wu X,Ma K,Liu W,Liu P,Hayashi T,Mizuno K,Hattori S,Fujisaki H,Ikejima T
Sat Jul 15 00:00:00 UTC 2023
Silibinin alleviates ferroptosis of rat islet β cell INS-1 induced by the treatment with palmitic acid and high glucose through enhancing PINK1/parkin-mediated mitophagy.
Archives of biochemistry and biophysics
Du Q,Wu X,Ma K,Liu W,Liu P,Hayashi T,Mizuno K,Hattori S,Fujisaki H,Ikejima T
Sat Jul 15 00:00:00 UTC 2023
Overexpression of GPX4 attenuates cognitive dysfunction through inhibiting hippocampus ferroptosis and neuroinflammation after traumatic brain injury.
Free radical biology & medicine
Fang J,Yuan Q,Du Z,Zhang Q,Yang L,Wang M,Yang W,Yuan C,Yu J,Wu G,Hu J
Tue Aug 01 00:00:00 UTC 2023
Embryonic 6:2 FTOH exposure causes reproductive toxicity by disrupting the formation of the blood-testis barrier in offspring mice.
Ecotoxicology and environmental safety
Xia Y,Hao L,Li Y,Li Y,Chen J,Li L,Han X,Liu Y,Wang X,Li D
Sun Jan 15 00:00:00 UTC 2023
Embryonic 6:2 FTOH exposure causes reproductive toxicity by disrupting the formation of the blood-testis barrier in offspring mice.
Ecotoxicology and environmental safety
Xia Y,Hao L,Li Y,Li Y,Chen J,Li L,Han X,Liu Y,Wang X,Li D
Sun Jan 15 00:00:00 UTC 2023
The licorice flavonoid isoliquiritigenin attenuates Mycobacterium tuberculosis-induced inflammation through Notch1/NF-κB and MAPK signaling pathways.
Journal of ethnopharmacology
Sun J,Zhang Q,Yang G,Li Y,Fu Y,Zheng Y,Jiang X
Wed Aug 10 00:00:00 UTC 2022
MiR-205-5p Functions as a Tumor Suppressor in Gastric Cancer Cells through Downregulating FAM84B.
Journal of oncology
Chen X,Zhang L,Geng J,Chen Z,Cui X
Sat Jul 16 00:00:00 UTC 2022
Burdock (Arctium lappa L.) leaf flavonoids rich in morin and quercetin 3-O-rhamnoside ameliorate lipopolysaccharide-induced inflammation and oxidative stress in RAW264.7 cells.
Food science & nutrition
Cui J,Zong W,Zhao N,Yuan R
Mon Aug 01 00:00:00 UTC 2022
Enhancement of the functionality of attenuating acute lung injury by a microemulsion formulation with volatile oil of Angelicae Sinensis Radix and Ligusticum Chuanxiong Rhizoma encapsulated.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhang L,Yan Q,Zhang W,Li X,Zhang X,Du S,Hua X,Lin J,Shu G,Peng G,Tan Z,Fu H
Thu Dec 01 00:00:00 UTC 2022
Catalpol ameliorates CFA-induced inflammatory pain by targeting spinal cord and peripheral inflammation.
Frontiers in pharmacology
Zhao B,Fu J,Ni H,Xu L,Xu C,He Q,Ni C,Wang Y,Kuang J,Tang M,Shou Q,Yao M
Fri Nov 11 00:00:00 UTC 2022
Morphological changes of macrophages and their potential contribution to tendon healing.
Colloids and surfaces. B, Biointerfaces
Yang QQ,Zhang L,Zhou YL,Tang JB
Sat Jan 01 00:00:00 UTC 2022
Combination of mitochondria impairment and inflammation blockade to combat metastasis.
Journal of controlled release : official journal of the Controlled Release Society
Yi X,Yan Y,Li L,Zhou R,Shen X,Huang Y
Sat Jan 01 00:00:00 UTC 2022
Combination of mitochondria impairment and inflammation blockade to combat metastasis.
Journal of controlled release : official journal of the Controlled Release Society
Yi X,Yan Y,Li L,Zhou R,Shen X,Huang Y
Sat Jan 01 00:00:00 UTC 2022
Golgi Phosphoprotein 3 Mediates Radiation-Induced Bystander Effect via ERK/EGR1/TNF-α Signal Axis.
Antioxidants (Basel, Switzerland)
Qin F,Chen G,Yu KN,Yang M,Cao W,Kong P,Peng S,Sun M,Nie L,Han W
Tue Nov 01 00:00:00 UTC 2022
Chicoric acid attenuates tumor necrosis factor-α-induced inflammation and apoptosis via the Nrf2/HO-1, PI3K/AKT and NF-κB signaling pathways in C28/I2 cells and ameliorates the progression of osteoarthritis in a rat model.
International immunopharmacology
Qu Y,Shen Y,Teng L,Huang Y,Yang Y,Jian X,Fan S,Wu P,Fu Q
Sat Oct 01 00:00:00 UTC 2022
The Protective Effect of Sulforaphane on Dextran Sulfate Sodium-Induced Colitis Depends on Gut Microbial and Nrf2-Related Mechanism.
Frontiers in nutrition
He C,Gao M,Zhang X,Lei P,Yang H,Qing Y,Zhang L
Sat Jul 16 00:00:00 UTC 2022
Forsythoside B attenuates neuro-inflammation and neuronal apoptosis by inhibition of NF-κB and p38-MAPK signaling pathways through activating Nrf2 post spinal cord injury.
International immunopharmacology
Xia M,Zhang Y,Wu H,Zhang Q,Liu Q,Li G,Zhao T,Liu X,Zheng S,Qian Z,Li H
Sat Oct 01 00:00:00 UTC 2022
Oxybaphus himalaicus Mitigates Lipopolysaccharide-Induced Acute Kidney Injury by Inhibiting TLR4/MD2 Complex Formation.
Antioxidants (Basel, Switzerland)
Zhan H,Pu Q,Long X,Lu W,Wang G,Meng F,Liao Z,Lan X,Chen M
Tue Nov 22 00:00:00 UTC 2022
Honokiol Ameliorates DSS-Induced Mouse Colitis by Inhibiting Inflammation and Oxidative Stress and Improving the Intestinal Barrier.
Oxidative medicine and cellular longevity
Wang L,Wang J
Fri Dec 30 00:00:00 UTC 2022
Glycyrrhizic Acid Alleviates Lipopolysaccharide (LPS)-Induced Acute Lung Injury by Regulating Angiotensin-Converting Enzyme-2 (ACE2) and Caveolin-1 Signaling Pathway.
Inflammation
Chen Y,Qu L,Li Y,Chen C,He W,Shen L,Zhang R
Tue Feb 01 00:00:00 UTC 2022
Glycyrrhizic Acid Alleviates Lipopolysaccharide (LPS)-Induced Acute Lung Injury by Regulating Angiotensin-Converting Enzyme-2 (ACE2) and Caveolin-1 Signaling Pathway.
Inflammation
Chen Y,Qu L,Li Y,Chen C,He W,Shen L,Zhang R
Tue Feb 01 00:00:00 UTC 2022
Atorvastatin attenuates ferroptosis-dependent myocardial injury and inflammation following coronary microembolization via the Hif1a/Ptgs2 pathway.
Frontiers in pharmacology
Liu T,Shu J,Liu Y,Xie J,Li T,Li H,Li L
Tue Dec 27 00:00:00 UTC 2022
Network analysis and experimental pharmacology study explore the protective effects of Isoliquiritigenin on 5-fluorouracil-Induced intestinal mucositis.
Frontiers in pharmacology
Liao YF,Luo FL,Tang SS,Huang JW,Yang Y,Wang S,Jiang TY,Man Q,Liu S,Wu YY
Tue Oct 25 00:00:00 UTC 2022
The ethanol extract of flower buds of Tussilago farfara L. attenuates cigarette smoke-induced lung inflammation through regulating NLRP3 inflammasome, Nrf2, and NF-κB.
Journal of ethnopharmacology
Xu LT,Wang T,Fang KL,Zhao Y,Wang XN,Ren DM,Shen T
Sun Jan 30 00:00:00 UTC 2022
Isoalantolactone (IAL) Regulates Neuro-Inflammation and Neuronal Apoptosis to Curb Pathology of Parkinson's Disease.
Cells
He D,Liu Y,Li J,Wang H,Ye B,He Y,Li Z,Gao X,Fu S,Liu D
Mon Sep 19 00:00:00 UTC 2022
Lipoxin A4 protects primary spinal cord neurons from Erastin-induced ferroptosis by activating the Akt/Nrf2/HO-1 signaling pathway.
FEBS open bio
Wei N,Lu T,Yang L,Dong Y,Liu X
Sun Aug 01 00:00:00 UTC 2021
TFAM knockdown-triggered mtDNA-nucleoid aggregation and a decrease in mtDNA copy number induce the reorganization of nucleoid populations and mitochondria-associated ER-membrane contacts.
Biochemistry and biophysics reports
Aasumets K,Basikhina Y,Pohjoismäki JL,Goffart S,Gerhold J
Wed Dec 01 00:00:00 UTC 2021
Programmable Polymeric Microneedles for Combined Chemotherapy and Antioxidative Treatment of Rheumatoid Arthritis.
ACS applied materials & interfaces
Wu C,Cheng J,Li W,Yang L,Dong H,Zhang X
Wed Nov 24 00:00:00 UTC 2021
Programmable Polymeric Microneedles for Combined Chemotherapy and Antioxidative Treatment of Rheumatoid Arthritis.
ACS applied materials & interfaces
Wu C,Cheng J,Li W,Yang L,Dong H,Zhang X
Wed Nov 24 00:00:00 UTC 2021
Celecoxib reverses the glioblastoma chemo-resistance to temozolomide through mitochondrial metabolism.
Aging
Yin D,Jin G,He H,Zhou W,Fan Z,Gong C,Zhao J,Xiong H
Wed Sep 08 00:00:00 UTC 2021
hsa-miR-15b-5p regulates the proliferation and apoptosis of human vascular smooth muscle cells by targeting the ACSS2/PTGS2 axis.
Experimental and therapeutic medicine
Gan S,Mao J,Pan Y,Tang J,Qiu Z
Mon Nov 01 00:00:00 UTC 2021
Topical hypochlorous acid (HOCl) blocks inflammatory gene expression and tumorigenic progression in UV-exposed SKH-1 high risk mouse skin.
Redox biology
Jandova J,Snell J,Hua A,Dickinson S,Fimbres J,Wondrak GT
Wed Sep 01 00:00:00 UTC 2021
Protective effect of scorpion venom heat-resistant synthetic peptide against PM2.5-induced microglial polarization via TLR4-mediated autophagy activating PI3K/AKT/NF-κB signaling pathway.
Journal of neuroimmunology
Xu X,Xu H,Ren F,Huang L,Xu J,Li F
Tue Jun 15 00:00:00 UTC 2021
Silencing of PTX3 alleviates LPS-induced inflammatory pain by regulating TLR4/NF-κB signaling pathway in mice.
Bioscience reports
Qi S,Zhao F,Li Z,Liang F,Yu S
Fri Feb 28 00:00:00 UTC 2020
Sweroside Alleviated LPS-Induced Inflammation via SIRT1 Mediating NF-κB and FOXO1 Signaling Pathways in RAW264.7 Cells.
Molecules (Basel, Switzerland)
Wang R,Dong Z,Lan X,Liao Z,Chen M
Fri Mar 01 00:00:00 UTC 2019
Ajudecumin A from Ajuga ovalifolia var. calantha exhibits anti-inflammatory activity in lipopolysaccharide-activated RAW264.7 murine macrophages and animal models of acute inflammation.
Pharmaceutical biology
Zhang H,Ren QC,Ren Y,Zhao L,Yang F,Zhang Y,Zhao WJ,Tan YZ,Shen XF
Sat Dec 01 00:00:00 UTC 2018
