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Application
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COX6c/Cytochrome C Oxidase subunit VIc Antibody (BS-12925R) in IHC (P)
Paraformaldehyde-fixed, paraffin embedded mouse placenta; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with COX6c/Cytochrome C Oxidase subunit VIc Polyclonal Antibody, Unconjugated (bs-12925R) at 1:400 overnight at 4°C, followed by a conju... View More
Product Details
BS-12925R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human COX6c/Cytochrome C Oxidase subunit VIc, amino acids 21-75.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cytochrome c oxidase polypeptide VIc; Cytochrome c oxidase polypeptide VIc-2; Cytochrome c oxidase subunit 6C; Cytochrome c oxidase subunit 6C-2; cytochrome c oxidase subunit VIc preprotein; cytochrome oxidase subunit VIc; EC 1.9.3.1
Gene Aliases: COVIc; COX-VIc; COX6C; Cox6c2
UniProt ID: (Human) P09669, (Mouse) Q9CPQ1, (Rat) P11951
Entrez Gene ID: (Human) 1345, (Mouse) 12864, (Rat) 54322
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