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Application
FIGURE: 1 / 1
CPSF1 Antibody (PA5-67022) in ICC/IF
Immunofluorescent staining of CPSF1 in human cell line MCF7 shows localization to nucleoplasm. Samples were probed using a CPSF1 Polyclonal Antibody (Product # PA5-67022).
Product Details
PA5-67022
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human CPSF1. Recombinant protein control fragment (Product #RP-107662).
Conjugate
Unconjugated
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2663196
Product Specific Information
Immunogen sequence: AISLNITQKVH PVIWSLTSLP FDCTQALAVP KPIGGVVVFA VNSLLYLNQS VPPYGVALNS LTTGTTAFPL RT
Highest antigen sequence identity to the following orthologs - mouse 99%, rat 99%.
Target Information
Midline-1 (Tripartite motif-containing protein 18, Putative transcription factor XPRF, RING finger protein 59) is a 667 amino acid protein encoded by the human gene MID1. Midline-1 belongs to the TRIM/RBCC family and contains two B box-type zinc fingers, one B30.2/SPRY domain, one COS domain, one fibronectin type-III domain and one RING-type zinc finger. Midline-1 is believed to have E3 ubiquitin ligase activity which targets the catalytic subunit of protein phosphatase 2 for degradation. It is a cytoplasmic protein found as a homodimer or heterodimer with Midline-2. It also interacts with IGBP1 (Lymphocyte signaling protein A4). Defects in MID1 are the cause of Opitz syndrome type I (OS-I). OS-I is an X-linked recessive disorder characterized by hypertelorism, genital-urinary defects such as hypospadias in males and splayed labia in females, lip-palate-laryngotracheal clefts, imperforate anus, developmental delay and congenital heart defects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cleavage and polyadenylation specific factor 1, 160kDa; Cleavage and polyadenylation specificity factor 160 kDa subunit; Cleavage and polyadenylation specificity factor subunit 1; CPSF 160 kDa subunit; polyadenylation specificity factor
Gene Aliases: CPSF1; CPSF160; HSU37012; P/cl.18
UniProt ID: (Human) Q10570
Entrez Gene ID: (Human) 29894
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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