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Immunogen sequence: MFCTSGGNS ASVMSMRPVP GSLSSLLHLH NRQRQPMPAS MPGTLPNPTM PGSSAVLMPM ERQMSVNSSI MGMQGPNLSN PCASPQVQPM HSEAKMRLKA ALTHHPAAMS NGNMNTMGHM MEMMGSRQDQ TPHHHMHSHP HQHQTLPPHH PYPHQHQHPA HHPHPQPHHQ QNHPHHHSHS HLHAHPAHHQ TSPHPPLHTG NQAQVSPATQ QMQPTQTIQP PQPTGGRRRR VVDEDPDERR RKFLERNRAA ATRCRQKRKV WVMSLEKKAE ELTQTNMQLQ NEVSMLKNEV AQLKQLLLTH KDCPITAMQK ESQGYLSPES SPPASPVPAC SQQQVIQHNT ITTSSSVSEV VGSSTLSQLT THRTDLNPIL (1-369 aa encoded by BC059400)
The product of this gene belongs to the CRE (cAMP response element)-binding protein family. Members of this family contain zinc-finger and bZIP DNA-binding domains. The encoded protein specifically binds to CRE as a homodimer or a heterodimer with c-Jun or CRE-BP1, and functions as a CRE-dependent trans-activator. Alternatively spliced transcript variants encoding different isoforms have been identified.
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Protein Aliases: cAMP response element-binding protein CRE-BPa; cAMP-response element-binding protein A; CRE-BPa; CREB-5; Cyclic AMP-responsive element-binding protein 5
Gene Aliases: CRE-BPA; CREB-5; CREB5; CREBPA
UniProt ID: (Human) Q02930
Entrez Gene ID: (Human) 9586
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