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Product Details
PA5-54501
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CROCC. Recombinant protein control fragment (Product #RP-93572).
Conjugate
Unconjugated
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2640169
Product Specific Information
Immunogen sequence: LEAEKEELSE EIAALQQERD EGLLLAESEK QQALSLKESE KTALSEKLMG TRHSLATISL EMERQKRDAQ SRQEQDRSTV NALTSELRDL R
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 97%.
Target Information
Major structural component of the ciliary rootlet, a cytoskeletal-like structure in ciliated cells which originates from the basal body at the proximal end of a cilium and extends proximally toward the cell nucleus. Furthermore, is required for the correct positioning of the cilium basal body relative to the cell nucleus, to allow for ciliogenesis (PubMed:27623382). Contributes to centrosome cohesion before mitosis (PubMed:16203858). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ciliary rootlet coiled-coil protein; CROCC; Rootletin; rootletin, ciliary rootlet protein; Tax1-binding protein 2
Gene Aliases: CROCC; KIAA0445; ROLT
UniProt ID: (Human) Q5TZA2
Entrez Gene ID: (Human) 9696
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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