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Bethyl Laboratories
CRSP2/DRIP150 Polyclonal Antibody
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Application
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CRSP2/DRIP150 Antibody (A301-044A) in WB
Detection of human CRSP2-DRIP150 by western blot. Samples: Whole cell lysate (50 µg) from HEK293T, Jurkat, MCF-7, LNCaP, and HeLa cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-CRSP2-DRIP150 antibody (Product # A301-044A lot 2) used for WB at 1 µg/mL. Detection: Chemiluminescence with an exposure time of 3 minutes.
Product Details
A301-044A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 1 and 50 of human cofactor required for Sp1 transcriptional activation, subunit 2 (vitamin D receptor-interacting protein complex component DRIP150).
Conjugate
Unconjugated
Form
Liquid
Concentration
1.0 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Activator-recruited cofactor 150 kDa component; ARC150; Cofactor required for Sp1 transcriptional activation subunit 2; cofactor required for Sp1 transcriptional activation, subunit 2 (150kD); CRSP complex subunit 2; DRIP150; hRGR1; human homolog of yeast RGR1; Mediator complex subunit 14; Mediator of RNA polymerase II transcription subunit 14; MGC104513; RGR1 homolog; Thyroid hormone receptor-associated protein complex 170 kDa component; thyroid hormone receptor-associated protein complex component TRAP170; transcriptional co-activator CRSP150; Transcriptional coactivator CRSP150; Trap170; vitamin D receptor-interacting protein complex component DRIP150; Vitamin D3 receptor-interacting protein complex 150 kDa component
Gene Aliases: ARC150; CRSP150; CRSP2; CSRP; CXorf4; DRIP150; EXLM1; MED14; RGR1; TRAP170
UniProt ID: (Human) O60244
Entrez Gene ID: (Human) 9282
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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