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Bethyl Laboratories
CSN4 Polyclonal Antibody
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Application
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CSN4 Antibody (A300-013A) in WB
Detection of human and mouse CSN4 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, Jurkat, mouse TCMK-1, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-CSN4 antibody (Product # A300-013A) (lot A300-013A-2) used for WB at 0.1 µg/mL. Detection: Chemiluminescence with an exposure time of 3 minutes.
Product Details
A300-013A
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residues 350 and the C-terminus (residue 406) of human COP9 constitutive photomorphogenic homolog subunit 4.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Bovine, Pig and Orangutan
Target Information
This gene encodes one of eight subunits composing COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: COP9 (constitutive photomorphogenic), subunit 4; COP9 complex S4; COP9 constitutive photomorphogenic homolog subunit 4; COP9 constitutive photomorphogenic-like protein subunit 4; COP9 signalosome complex subunit 4; JAB1-containing signalosome subunit 4; SGN4; signalosome subunit 4; testis tissue sperm-binding protein Li 42a
Gene Aliases: AW208976; COPS4; CSN4; D5Ertd774e
UniProt ID: (Human) Q9BT78, (Mouse) O88544
Entrez Gene ID: (Human) 51138, (Mouse) 26891
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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