Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Recommended positive controls: Jurkat.
Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (94%), Xenopus laevis (96%), Chicken (95%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
CSTF2 is one of three (including CSTF1 and CSTF3) cleavage stimulation factors which combine to form CSTF which is involved in the polyadenylation and 3'end cleavage of pre-mRNAs. CSTF2 contains a ribonucleoprotein-type RNA binding domain. CSTF2 is upregulated during activation of B cells which results in the switch of IgM heavy chain mRNA from membrane bound form to the secreted form.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: betaCstF-64 variant 2; CF-1 64 kDa subunit; Cleavage stimulation factor 64 kDa subunit; Cleavage stimulation factor subunit 2; cleavage stimulation factor, 3' pre-RNA, subunit 2; cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kD; cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa; CstF 64; CSTF 64 kDa subunit
Gene Aliases: CstF-64; CSTF2
UniProt ID: (Human) P33240
Entrez Gene ID: (Human) 1478
Molecular Function:
mRNA polyadenylation factor
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