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Product Details
PA5-139817
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CTC1. Recombinant protein control fragment (Product #RP-108894).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2926819
Product Specific Information
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: CASCLTVQDN WTLELESSQD IQDVLDANKS LPESSLTDLL SDNFTDSLVS FSAEILSRTL CEPLVASLWM KLGNTGAMRR CVKLTVALET AECEFPPHLD VYIEDPHLPP SLGLLPGARV HFSQLEKRVS RSHNVYCCFR SSTY
Target Information
CQ068 is subunits of an alpha accessory factor (AAF) that stimulates the activity of DNA polymerase-alpha-primase (see MIM 176636), the enzyme that initiates DNA replication. CQ068 also appears to function in a telomere-associated complex with OBFC1 and TEN1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha accessory factor 132; conserved telomere capping protein 1; Conserved telomere maintenance component 1; CST complex subunit CTC1; HBV DNAPTP1-transactivated protein B
Gene Aliases: AAF-132; AAF132; C17orf68; CRMCC; CTC1; tmp494178
UniProt ID: (Human) Q2NKJ3
Entrez Gene ID: (Human) 80169
telomere maintenance
cellular response to DNA damage stimulus
regulation of G2/M transition of mitotic cell cycle
telomere maintenance via telomere lengthening
multicellular organism growth
positive regulation of DNA replication
positive regulation of fibroblast proliferation
spleen development
thymus development
bone marrow development
negative regulation of telomerase activity
hematopoietic stem cell proliferation
replicative senescence
regulation of telomere maintenance via telomere lengthening
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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