Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
PA5-84704
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human C1QTNF3. Recombinant protein control fragment (Product #RP-107472).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Anitgen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2791855
Product Specific Information
Immunogen sequence: CQDEYMESPQ TGGLPPDCSK CCHGDYSFRG YQG
Target Information
Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. Multiple isoforms of human CTRP3 have been reported. It has been suggested that CTRP3 may play a role in skeletal development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: cartonectin; Collagenous repeat-containing sequence 26 kDa protein; collagenous repeat-containing sequence of 26-kDa; Complement C1q tumor necrosis factor-related protein 3; CORS26; Secretory protein CORS26
Gene Aliases: C1ATNF3; C1QTNF3; CORCS; CORS; CORS-26; CORS26; CTRP3; UNQ753/PRO1484
UniProt ID: (Human) Q9BXJ4
Entrez Gene ID: (Human) 114899
cellular triglyceride homeostasis
negative regulation of NF-kappaB import into nucleus
fat cell differentiation
negative regulation of gluconeogenesis
positive regulation of cytokine secretion
negative regulation of inflammatory response
positive regulation of adiponectin secretion
protein trimerization
negative regulation of monocyte chemotactic protein-1 production
negative regulation of interleukin-6 secretion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support