Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 1
Immunogen sequence: HVLGAGGGPG PTQGEEQPPQ PPLDPQNLAR PPAPAQTEAL SQLFCSVRTL TAKEELLQTL RTHLILHMAR AHGYSKVMTG DSCTRLAIKL MTNLALGRGA FLAWDTGFSD ERHGDVVVVR PMRDHTLKEV AFYNRLFSVP SVFTPAVDTK APEKASIHRL MEAFILRLQT QFPSTVSTVY RTSEKLVKGP RDGPAAGDSG PRCLLCMCAL DVDAADSATA FGAQTSSRLS QMQSPIPLTE TRTPPGPCCS PGVGWAQRCG QGACRREDPQ ACIEEQLCYS CRVNMKDLPS LDPLPPYILA EAQLRTQRAW GLQEIRDCLI EDSDDEAGQS; Positive Samples: A-431, Jurkat; Cellular Location: Cytoplasm
Cytoplasmic tRNA 2-thiolation protein 2 (CUT2), also named as C16orf84 or NCS2, is a 515 amino acid protein, which belongs to the CUT2 family. C16orf84 localizes in the cytoplasm and Plays a central role in 2-thiolation of mcm5S2U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). C16orf84 may act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thio-carboxylated URM1 onto the uridine of tRNAs at wobble position.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cytoplasmic tRNA 2-thiolation protein 2; Cytosolic thiouridylase subunit 2; cytosolic thiouridylase subunit 2 homolog
Gene Aliases: C16orf84; CTU2; NCS2; UPF0432
UniProt ID: (Human) Q2VPK5
Entrez Gene ID: (Human) 348180
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support