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Alomone Labs, LTD
CX3CR1 (extracellular) Polyclonal Antibody, APC
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Application
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CX3CR1 (extracellular) Antibody (ACR-058-APC-50UL) in Flow
Cell surface detection of CX3CR1 by direct flow cytometry in live intact mouse J774 macrophage cells. Black line: Cells. Red line: Cells + Rabbit IgG Isotype Control-APC (#RIC-001-APC). Green line: Cells + Anti-CX3CR1 (extracellular)-APC Antibody (#ACR-058-APC) (2.5 µg).
Product Details
ACR-058-APC-50UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide HQPSLDQPAIPSSKAT, corresponding to amino acid residues 413-428 of rat TRPV2. Extracellular, 1st loop.
Conjugate
Excitation/Emission Max
651/660 nm
View spectra
Form
Lyophilized
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Immunogen sequence: HQPSLDQPAIPSSKAT
Reconstitution: 50 uL double distilled water (DDW). The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively. The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1. Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine. CX3CR1 mediates leukocyte migration an d adhesion. CX3CR1 is expressed in a variety of human tissues and cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C-X3-C CKR-1; chemokine (C-X3-C) receptor 1; Cx3c; CX3C chemokine receptor 1; Fractalkine receptor; Scyd1
Gene Aliases: Cx3cr1; Rbs11
UniProt ID: (Rat) P35411, (Mouse) Q9Z0D9
Entrez Gene ID: (Rat) 171056, (Mouse) 13051
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