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Search Thermo Fisher Scientific
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Immunogen sequence: DYPAFFNFTK GNGIAFSSGD RWKVLRQFSI QILRNFGMGK RSIEERILEE GSFLLAELRK TEGEPFDPTF VLSRSVSNII CSVLFGSRFD YDDERLLTII RLINDNFQIM SSPWGELYDI FPSLLDWVPG PHQRIFQNFK CLRDLIAHSV HDHQASLDPR SPRDFIQCFL TKMAEEKEDP LSHFHMDTLL M; Positive Samples: SW620, BT-474, Mouse lung, Mouse liver, Rat liver, Rat brain; Cellular Location: Endoplasmic reticulum membrane, Microsome membrane, Peripheral membrane protein
CYP2F1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to dehydrogenate 3-methylindole, an endogenous toxin derived from the fermentation of tryptophan, as well as xenobiotic substrates such as naphthalene and ethoxycoumarin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CYPIIF1; CYPIIF2; Cytochrome P450 2F1; Cytochrome P450 2F2; cytochrome P450, family 2, subfamily F, polypeptide 1; cytochrome P450, family 2, subfamily f, polypeptide 2; cytochrome P450, subfamily 2F, polypeptide 1; Cytochrome P450, subfamily IIF, polypeptide 1; Cytochrome P450-NAH-2; flavoprotein-linked monooxygenase; microsomal monooxygenase; Naphthalene dehydrogenase; Naphthalene hydroxylase; P450-NAH-2; xenobiotic monooxygenase
Gene Aliases: C2F1; CYP2F; CYP2F1; Cyp2f2; Cyp2f4; CYP4502F4; CYPIIF1
UniProt ID: (Human) P24903, (Rat) O35293
Entrez Gene ID: (Human) 1572, (Rat) 54246
Molecular Function:
oxidoreductase
oxygenase
metabolite interconversion enzyme
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