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NeoBiotechnologies
Calbindin 1 (CALB1) Monoclonal Antibody (CALB1, 3333)
Application
FIGURE: 1 / 4
Calbindin 1 (CALB1) Antibody (793-MSM3-P1) in IHC (P)
Immunohistochemistry (Paraffin) analysis performed in formalin fixed, paraffin-embedded human kidney using Calbindin 1 (CALB1) Monoclonal Antibody (Product # 793-MSM3-P1).
Product Details
793-MSM3-P1
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b, kappa
Class
Monoclonal
Type
Antibody
Clone
CALB1, 3333
Immunogen
Recombinant fragment (around aa 7-96) of human CALB1 protein
Conjugate
Unconjugated
Form
Liquid
Concentration
200 µg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
4° C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.
Target Information
Calbindin-D-28K (also termed vitamin D-dependent calcium-binding protein, or cholecalcin), is a highly conserved 28kDa calcium binding protein, with broad tissue distribution. It belongs, together with calmodulin, S-100, parvalbumin, troponin C and other proteins, to a family of low molecular weight calcium-binding proteins (CaBPs). These CaBPs have homologous primary structures, which contain conserved polypeptide folds of the EF-hand type for Ca2+ binding. Calbindin-D-28K is found predominantly in subpopulations of central and peripheral nervous system neurons, and in certain epithelial nervous system neurons, and in certain epithelial cells involved in Ca2+ transport such as distal tubular cells and cortical collecting tubules of the kidney, and in enteric neuroendocrine cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Calbindin; calbindin 1, (28kD); calbindin 1, 28kDa; Calbindin D28; D-28K; RTVL-H protein; Vitamin D-dependent calcium-binding protein, avian-type
Gene Aliases: CAB27; CALB; CALB1; D-28K
UniProt ID: (Human) P05937
Entrez Gene ID: (Human) 793
short-term memory
long-term memory
locomotory behavior
retina layer formation
metanephric part of ureteric bud development
regulation of synaptic plasticity
regulation of cytosolic calcium ion concentration
cellular response to organic substance
metanephric collecting duct development
metanephric distal convoluted tubule development
metanephric connecting tubule development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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