Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 2
Positive test controls include: SKOV3, Mouse thymus, Mouse brain, Mouse spinal cord.
Immunogen sequence: GAWTLHEDPR QNRGGGCINH KDTFFQNPQY IFEVKKPEDE VLICIQQRPK RSTRREGKGE NLAIGFDIYK VEENRQYRMH SLQHKAASSI YINSRSVFLR TDQPEGRYVI IPTTFEPGHT GEFLLRVFTD VPSNCRELRL DEPPHTCWSS LCGYPQLVTQ VHVLGAAGLK DSPTGANSYV IIKCEGDKVR SAVQKGTSTP EYNVKGIFYR KKLSQPITVQ VWNHRVLKDE FLGQVHLKAD PDNLQALHTL HLRDRNSRQP SNLPGTVAVH ILSSTSLMAV
Calpains are calcium-dependent cysteine proteases involved in signal transduction in a variety of cellular processes. A functional calpain protein consists of an invariant small subunit and 1 of a family of large subunits. CAPN5 is one of the large subunits. Unlike some of the calpains, CAPN5 and CAPN6 lack a calmodulin-like domain IV. Because of the significant similarity to Caenorhabditis elegans sex determination gene tra-3, CAPN5 is also called as HTRA3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Calpain htra-3; Calpain-5; high-temperature requirement factor A3; nCL-3; New calpain 3; testis tissue sperm-binding protein Li 91mP
Gene Aliases: ADNIV; CAPN5; HTRA3; nCL-3; NCL3; VRNI
UniProt ID: (Human) O15484, (Mouse) O08688
Entrez Gene ID: (Human) 726, (Mouse) 12337, (Rat) 171495
Molecular Function: cysteine protease
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support