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Invitrogen
Caplacizumab Humanized Recombinant Human Monoclonal Antibody
FIGURE: 1 / 1
Caplacizumab Humanized Antibody (MA5-41954) in SDS-PAGE
SDS-PAGE analysis of the recombinant Human VWF A1 domain protein expressed in CHO cells using a Caplacizumab biosimilar monoclonal antibody (Product # MA5-41954). R denotes the lane was run under reducing conditions. NR denotes the lane was run under non-reducing conditions.
Product Details
MA5-41954
Product Specifications
Species Reactivity
Human
Host/Isotype
Human
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Immunogen
Human VWF A1 domain
Conjugate
Form
Liquid
Concentration
1.6 mg/mL
Purification
Metal-chelate chromatography
Storage buffer
20mM citric acid with 6.2% sucrose, 0.01% Tween 80
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2911097
Product Specific Information
Endotoxin level < 0.01EU/µg by LAL method
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.
Target Information
Caplacizumab, firstly called ALX-0081, is a humanized single-variable-domain immunoglobulin consisting of two identical humanized building blocks genetically linked by a three-alanine linker. Caplacizumab was developed by Ablynx, a Sanofi company and FDA approved on February 6, 2019, 6and approved previously by the EU in October 2018 as a combination therapy with plasma exchange and immunosuppression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ALX-0081; caplacizumab-yhdp; PMP12A2h1-linker AAA-PMP12A2h1; VWF A1 domain
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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