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ACTC1 are part of actins, which are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: actin alpha cardiac; Actin, alpha cardiac muscle 1; Alpha-cardiac actin; alphac-actin
Gene Aliases: ACTC; Actc-1; ACTC1; ASD5; CMD1R; CMH11; LVNC4
UniProt ID: (Human) P68032, (Bovine) Q3ZC07, (Chicken) P04270, (Mouse) P68033
Entrez Gene ID: (Human) 70, (Rabbit) 100340339, (Bovine) 533219, (Chicken) 423298, (Mouse) 11464
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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