Product References
Fiber density and matrix stiffness modulate distinct cell migration modes in a 3D stroma mimetic composite hydrogel.
Acta biomaterialia
Hiraki HL,Matera DL,Wang WY,Prabhu ES,Zhang Z,Midekssa F,Argento AE,Buschhaus JM,Humphries BA,Luker GD,Pena-Francesch A,Baker BM
700182 was used in Immunocytochemistry-immunofluorescence to establish a composite approach to modulate fibrous topography and bulk hydrogel mechanics and identified biomaterial parameters to direct distinct 3D cell migration phenotypes.
Thu Jun 01 00:00:00 EDT 2023
FACT maintains nucleosomes during transcription and stem cell viability in adult mice.
EMBO reports
Goswami I,Sandlesh P,Stablewski A,Toshkov I,Safina AF,Magnitov M,Wang J,Gurova K
700182 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to indicate that FACT maintains chromatin integrity during transcription in mammalian adult stem cells, suggesting that chromatin transcription in stem cells and differentiated cells is different.
Tue Apr 05 00:00:00 EDT 2022
miR-431-5p regulates apoptosis of cardiomyocytes after acute myocardial infarction via targeting selenoprotein T.
Physiological research
Geng H,Chen L,Su Y,Xu Q,Fan M,Huang R,Li X,Lu X,Pan M
700182 was used in Western Blotting to show that the expression of miR-431-5p in AMI myocardial tissues and H/R-induced HL-1 cardiomyocytes was significantly increased.
Fri Mar 25 00:00:00 EDT 2022
Denatonium as a Bitter Taste Receptor Agonist Modifies Transcriptomic Profile and Functions of Acute Myeloid Leukemia Cells.
Frontiers in oncology
Salvestrini V,Ciciarello M,Pensato V,Simonetti G,Laginestra MA,Bruno S,Pazzaglia M,De Marchi E,Forte D,Orecchioni S,Martinelli G,Bertolini F,Méndez-Ferrer S,Adinolfi E,Di Virgilio F,Cavo M,Curti A
700182 was used in Immunocytochemistry to show that AML cells express functional TAS2Rs.
Mon Apr 26 00:00:00 EDT 2021
HERC1 Ubiquitin Ligase Is Required for Hippocampal Learning and Memory.
Frontiers in neuroanatomy
Pérez-Villegas EM,Pérez-Rodríguez M,Negrete-Díaz JV,Ruiz R,Rosa JL,de Toledo GA,Rodríguez-Moreno A,Armengol JA
700182 was used in Immunohistochemistry to study the tbl hippocampus using behavioral tests, ex vivo electrophysiological recordings, immunohistochemistry, the Golgi-Cox method and transmission electron microscopy.
Fri Nov 10 00:00:00 EST 2023
HERC1 Ubiquitin Ligase Is Required for Hippocampal Learning and Memory.
Frontiers in neuroanatomy
Pérez-Villegas EM,Pérez-Rodríguez M,Negrete-Díaz JV,Ruiz R,Rosa JL,de Toledo GA,Rodríguez-Moreno A,Armengol JA
700182 was used in Immunohistochemistry to study the tbl hippocampus using behavioral tests, ex vivo electrophysiological recordings, immunohistochemistry, the Golgi-Cox method and transmission electron microscopy.
Fri Nov 10 00:00:00 EST 2023
Silencing of soluble epoxide hydrolase 2 gene reduces H2O2-induced oxidative damage in rat intestinal epithelial IEC-6 cells via activating PI3K/Akt/GSK3β signaling pathway.
Cytotechnology
Li J,Luo J,Zhang Y,Tang C,Wang J,Chen C
700182 was used in Western Blotting to explore the effects and molecular mechanism of siEPHX2 on H2O2-induced oxidative damage in rat intestinal epithelial IEC-6 cells.
Sat Feb 01 00:00:00 EST 2020
Repurposing Quinacrine for Treatment of Malignant Mesothelioma: In-Vitro Therapeutic and Mechanistic Evaluation.
International journal of molecular sciences
Kulkarni NS,Vaidya B,Parvathaneni V,Bhanja D,Gupta V
700182 was used in Western Blotting to highlight anti-mesothelioma efficacy of QA at low doses, which can be instrumental in developing it as a stand-alone treatment strategy for MPM.
Mon Aug 31 00:00:00 EDT 2020
Repurposing Quinacrine for Treatment of Malignant Mesothelioma: In-Vitro Therapeutic and Mechanistic Evaluation.
International journal of molecular sciences
Kulkarni NS,Vaidya B,Parvathaneni V,Bhanja D,Gupta V
700182 was used in Western Blotting to highlight anti-mesothelioma efficacy of QA at low doses, which can be instrumental in developing it as a stand-alone treatment strategy for MPM.
Mon Aug 31 00:00:00 EDT 2020
Mitochondrial complex I inhibitor deguelin induces metabolic reprogramming and sensitizes vemurafenib-resistant BRAFV600E mutation bearing metastatic melanoma cells.
Molecular carcinogenesis
Carpenter EL,Chagani S,Nelson D,Cassidy PB,Laws M,Ganguli-Indra G,Indra AK
700182 was used in Western Blotting to show that treatment with metabolic regulators, can lead to energy starvation and so modulate the intracellular metabolic environment and reducing survival of drug-resistant melanomas harbouring BRAF V600E mutations.
Sun Sep 01 00:00:00 EDT 2019
Blockade of insulin receptor substrate-1 inhibits biological behavior of choroidal endothelial cells.
International journal of ophthalmology
Qian YY,Wu HY,Liu GQ,Ren C,Lu PR,Zhang XG
700182 was used in Western Blotting to investigate the effects of blockade of insulin receptor substrate-1 (IRS-1) on the bio-function of tube formation of human choroidal endothelial cells (HCECs).
Wed Sep 30 00:00:00 EDT 2020
Parthenolide inhibits the proliferation and induces the apoptosis of human uveal melanoma cells.
International journal of ophthalmology
Che ST,Bie L,Li X,Qi H,Yu P,Zuo L
700182 was used in Western Blotting to deduce that human uveal melanoma cell proliferation can be inhibited and apoptosis induced by parthenolide through the arrest of G1 phase and regulation of the mitochondrial pathway.
Thu Oct 01 00:00:00 EDT 2020
Design of Novel Inhibitors of Human Thymidine Phosphorylase: Synthesis, Enzyme Inhibition, in Vitro Toxicity, and Impact on Human Glioblastoma Cancer.
Journal of medicinal chemistry
de Moura Sperotto ND,Deves Roth C,Rodrigues-Junior VS,Ev Neves C,Reisdorfer Paula F,da Silva Dadda A,Bergo P,Freitas de Freitas T,Souza Macchi F,Moura S,Duarte de Souza AP,Campos MM,Valim Bizarro C,Santos DS,Basso LA,Machado P
700182 was used in Immunohistochemistry to evaluate novel pyrimidine-2,4-diones as inhibitors of human thymidine phosphorylase (hTP) activity.
Thu Feb 14 00:00:00 EST 2019
1,2,3,4,6-Penta-O-Galloyl-Beta-D-Glucopyranoside Inhibits Proliferation of Multiple Myeloma Cells Accompanied with Suppression of MYC Expression.
Frontiers in pharmacology
Tseeleesuren D,Kant R,Yen CH,Hsiao HH,Chen YA
700182 was used in Western Blotting to provide useful insights into the combination of MYC and proteasome-inhibitors for MM therapy.
Wed Sep 30 00:00:00 EDT 2020
Effects of Lycium barbarum polysaccharides on the damage to human endometrial stromal cells induced by hydrogen peroxide.
Molecular medicine reports
Shan T,Shan T,Liu F,Zheng H,Li G
700182 was used in Western Blotting to study the effects of Lycium barbarum polysaccharides on the damage to human endometrial stromal cells induced by hydrogen peroxide.
Wed Feb 01 00:00:00 EST 2017
Expression of FADD and cFLIPL balances mitochondrial integrity and redox signaling to substantiate apoptotic cell death.
Molecular and cellular biochemistry
Ranjan K,Pathak C
700182 was used in western blot to elucidate how FADD contributes to mitochondrial-associated apoptosis
Tue Nov 01 00:00:00 EDT 2016
Comparison of 2, 5, and 20 % O2 on the development of post-thaw human embryos.
Journal of assisted reproduction and genetics
Yang Y,Xu Y,Ding C,Khoudja RY,Lin M,Awonuga AO,Dai J,Puscheck EE,Rappolee DA,Zhou C
700182 was used in immunocytochemistry to characterize the development of post-thaw human embryos by comparing 2,5,a nd 20% O2 levels
Fri Jul 01 00:00:00 EDT 2016
Effect of memantine: A NMDA receptor blocker, on ethambutol-induced retinal injury.
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft
Abdel-Hamid AA,Firgany Ael-D,Ali EM
700182 was used in immunohistochemistry - paraffin section to study ethambutol-induced retinal injury and the effect of memantine, an NMDA receptor blocker
Tue Mar 01 00:00:00 EST 2016
Identification of 1,2,3,4,6-Penta-O-galloyl-β-d-glucopyranoside as a Glycine N-Methyltransferase Enhancer by High-Throughput Screening of Natural Products Inhibits Hepatocellular Carcinoma.
International journal of molecular sciences
Kant R,Yen CH,Lu CK,Lin YC,Li JH,Chen YM
700182 was used in western blot to employ the method of high-throughput screening of natural products that inhibit hepatocellular carcinoma by identifying 1,2,3,4,6-Penta-O-galloyl-beta-d-glucopyranoside as a glycine N-methyltransferase enhancer
Wed May 04 00:00:00 EDT 2016
PARP-1 depletion in combination with carbon ion exposure significantly reduces MMPs activity and overall increases TIMPs expression in cultured HeLa cells.
Radiation oncology (London, England)
Ghorai A,Sarma A,Chowdhury P,Ghosh U
700182 was used in immunocytochemistry assess the effects of combining PARP-1 inhibition with carbon ion exposure to control metastatic cells
Thu Sep 22 00:00:00 EDT 2016
Investigating the role of shape on the biological impact of gold nanoparticles in vitro.
Nanomedicine (London, England)
Tian F,Clift MJ,Casey A,Del Pino P,Pelaz B,Conde J,Byrne HJ,Rothen-Rutishauser B,Estrada G,de la Fuente JM,Stoeger T
700182 was used in western blot to assess the impact of gold nanoparticle geometry on the biochemical response of Calu-3 epithelial cells.
Tue Jul 19 00:00:00 EDT 2016
Detection and quantification of apoptosis in primary cells using Taqman® protein assay.
Methods in molecular biology (Clifton, N.J.)
Pfister C,Pfrommer H,Tatagiba MS,Roser F
700182 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to describe apoptosis detection and quantification by an innovative method named TaqMan(®) protein assay.
Tue Jun 23 00:00:00 EDT 2015
Cardiac sympathetic afferent denervation attenuates cardiac remodeling and improves cardiovascular dysfunction in rats with heart failure.
Hypertension (Dallas, Tex. : 1979)
Wang HJ,Wang W,Cornish KG,Rozanski GJ,Zucker IH
700182 was used in Immunohistochemistry to suggest a potential new paradigm and therapeutic potential in the management of CHF.
Wed Oct 01 00:00:00 EDT 2014
Impact of diet deprivation and subsequent overallowance during gestation on mammary gland development and lactation performance.
Journal of animal science
Farmer C,Palin MF,Martel-Kennes Y
Wed Jan 01 00:00:00 EST 2014
Functional proteomic analysis reveals the involvement of KIAA1199 in breast cancer growth, motility and invasiveness.
BMC cancer
Jami MS,Hou J,Liu M,Varney ML,Hassan H,Dong J,Geng L,Wang J,Yu F,Huang X,Peng H,Fu K,Li Y,Singh RK,Ding SJ
Published figure using Caspase 3 monoclonal antibody (Product # 700182) in Immunohistochemistry
Sat Mar 15 00:00:00 EDT 2014
Functional proteomic analysis reveals the involvement of KIAA1199 in breast cancer growth, motility and invasiveness.
BMC cancer
Jami MS,Hou J,Liu M,Varney ML,Hassan H,Dong J,Geng L,Wang J,Yu F,Huang X,Peng H,Fu K,Li Y,Singh RK,Ding SJ
Published figure using Caspase 3 monoclonal antibody (Product # 700182) in Immunohistochemistry
Sat Mar 15 00:00:00 EDT 2014
Serial diffusion MRI to monitor and model treatment response of the targeted nanotherapy CRLX101.
Clinical cancer research : an official journal of the American Association for Cancer Research
Ng TS,Wert D,Sohi H,Procissi D,Colcher D,Raubitschek AA,Jacobs RE
700182 was used in immunohistochemistry to study the use of serial diffusion MRI to monitor the response to a cyclodextrin polymer nanoparticle containing a DNA topoisomerase I inhibitor in a murine lymphoma model
Wed May 01 00:00:00 EDT 2013
Detection and quantification of farnesol-induced apoptosis in difficult primary cell cultures by TaqMan protein assay.
Apoptosis : an international journal on programmed cell death
Pfister C,Pfrommer H,Tatagiba MS,Roser F
700182 was used in immunocytochemistry and western blot to develop a TaqMan protein assay of active caspase-3 to quantitate farnesol-induced apoptosis in primary cell cultures
Mon Apr 01 00:00:00 EDT 2013
Apoptosis-dependent acute lung injury and repair after intratracheal instillation of noradrenaline in rats.
Experimental physiology
Uhal BD,Rayford H,Zhuang J,Li X,Laukka J,Soledad-Conrad V
700182 was used in immunohistochemistry - paraffin section to assess intratracheal instillation of noradrenaline in rats and apoptosis-dependent acute lung injury and repair
Sat Mar 01 00:00:00 EST 2003