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            • Primary Antibodies ›
            • Chromogranin A Antibodies

            NeoBiotechnologies

            Chromogranin A/CHGA (Neuroendocrine Marker) Monoclonal Antibody (PHE5)

            View all (115) Chromogranin A antibodies
            Datasheet
            Protocols
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            Catalog # 1113-MSM3-P1ABX
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            Price (USD)
            610.00
            100 µg
             
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            Cite Chromogranin A/CHGA (Neuroendocrine Marker) Monoclonal Antibody (PHE5)

            • Antibody Testing Data (3)
            Application
            Chromogranin A/CHGA (Neuroendocrine Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Group 53 Created with Sketch.

            FIGURE: 1 / 3

            Chromogranin A/CHGA (Neuroendocrine Marker) Antibody (1113-MSM3-P1ABX) in IHC (P)

            Formalin-fixed, paraffin-embedded human Adrenal Gland stained with Chromogranin A Mouse Monoclonal Antibody (PHE5).
            View Product

            Chromogranin A/CHGA (Neuroendocrine Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Chromogranin A/CHGA (Neuroendocrine Marker) Antibody in SDS-PAGE (SDS-PAGE)
            Chromogranin A/CHGA (Neuroendocrine Marker) Antibody in SDS-PAGE (SDS-PAGE)

            Product Details

            1113-MSM3-P1ABX

            Applications
            Tested Dilution
            Publications

            Immunohistochemistry (Paraffin) (IHC (P))

            Assay-dependent
            -

            Immunohistochemistry (PFA fixed) (IHC (PFA))

            1-2 µg/mL
            -

            Immunocytochemistry (ICC/IF)

            1-2 µg/mL
            -

            Flow Cytometry (Flow)

            1-2 µg/10^6 cells
            -
            Product Specifications

            Species Reactivity

            Human, Non-human primate

            Host/Isotype

            Mouse / IgG1, kappa

            Class

            Monoclonal

            Type

            Antibody

            Clone

            PHE5

            Immunogen

            Human pheochromocytoma
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            1 mg/mL

            Purification

            Protein A/G

            Storage buffer

            PBS, pH 7.4

            Contains

            no preservative

            Storage conditions

            -20°C, Avoid Freeze/Thaw Cycles

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            Product Specific Information

            Does not react with Mouse or Rat

            Target Information

            Chromogranin A (CHGA) is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocine cells. CHGA is a precursor to three biologically active peptides: vasostatin, pancreastatin, and parastatin. These peptides act as autocine or paracrine negative modulators of the neuroendocrine system. CHGA is an excellent marker for carcinoid tumors, pheo-chromocytomas, paragangliomas, and other neuro-endocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: betagranin (N-terminal fragment of chromogranin A); catestatin; CgA; chromofungin; Chromogranin-A; CTNNB; DKFZp686D02253; FLJ25606; FLJ37923; MGC105435; parathyroid secretory protein 1; Pituitary secretory protein I; SP-I

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            Gene Aliases: CGA; CHGA

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            UniProt ID: (Human) Q9BQB5

            View more View less

            Entrez Gene ID: (Human) 1113

            View more View less

            Process(es)

            regulation of the force of heart contraction mast cell chemotaxis organelle organization regulation of blood pressure positive regulation of cAMP metabolic process killing of cells of other organism mast cell cytokine production negative regulation of catecholamine secretion ovulation cycle mast cell degranulation innate immune response mast cell activation negative regulation of vasodilation defense response to Gram-negative bacterium defense response to Gram-positive bacterium defense response to fungus positive regulation of cardiac muscle contraction adrenergic receptor signaling pathway involved in cardiac muscle relaxation positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway negative regulation of neuron death positive regulation of relaxation of cardiac muscle positive regulation of dense core granule biogenesis
            It has to be done as per old AB suggested Products section.
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