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            Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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            • Primary Antibodies ›
            • CRF Antibodies

            QED Bioscience

            Corticotropin Releasing Factor Monoclonal Antibody (4H9)

            View all (12) CRF antibodies
            Datasheet
            Protocols
            Questions & Answers
            Datasheet
            Protocols
            Questions & Answers

            Cite Corticotropin Releasing Factor Monoclonal Antibody (4H9)

            Product Details

            56101-100UG

            Applications
            Tested Dilution
            Publications

            Inhibition Assays (IA)

            Assay-dependent
            -
            Product Specifications

            Species Reactivity

            Human, Rat

            Host/Isotype

            Mouse / IgG1

            Class

            Monoclonal

            Type

            Antibody

            Clone

            4H9

            Immunogen

            Purified human/rat corticotropin-releasing factor (CRF, Sigma).
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            0.5-1.0 mg/mL

            Purification

            Protein A

            Storage buffer

            PBS, pH 7.4

            Contains

            no preservative

            Storage conditions

            -20°C, Avoid Freeze/Thaw Cycles

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            Target Information

            Corticotropin Releasing Factor (CRF), a 41 amino acids neuropeptide, belongs to a family of structurally related peptides including urocortin, sauvagine and urotensin I. CRF is critical in the regulation of the pituitary-adrenal gland axis, and in endocrine, autonomic and behavioral responses to stress. CRF is widely distributed in the brain and peripheral nervous system with the highest levels in the hypothalamic paraventricular nucleus.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: Corticoliberin; Corticotropin-releasing factor; Corticotropin-releasing hormone; CRF

            View more View less

            Gene Aliases: CRF; CRH; CRH1

            View more View less

            UniProt ID: (Human) P06850, (Rat) P01143

            View more View less

            Entrez Gene ID: (Human) 1392, (Rat) 81648

            View more View less

            Function(s)

            receptor binding hormone activity neuropeptide hormone activity protein binding corticotropin-releasing hormone activity corticotropin-releasing hormone receptor 1 binding corticotropin-releasing hormone receptor 2 binding peptide hormone

            Process(es)

            positive regulation of protein phosphorylation synaptic transmission, dopaminergic glucocorticoid biosynthetic process inflammatory response signal transduction chemical synaptic transmission female pregnancy parturition learning or memory positive regulation of cell proliferation associative learning hormone-mediated apoptotic signaling pathway positive regulation of gene expression negative regulation of gene expression negative regulation of norepinephrine secretion positive regulation of circadian sleep/wake cycle, wakefulness positive regulation of cell death regulation of serotonin secretion diterpenoid metabolic process hypothalamus development lung development adrenal gland development positive regulation of cAMP biosynthetic process negative regulation of epinephrine secretion negative regulation of luteinizing hormone secretion locomotory exploration behavior positive regulation of insulin secretion involved in cellular response to glucose stimulus response to immobilization stress negative regulation of circadian sleep/wake cycle, REM sleep response to drug response to estrogen response to ethanol response to ether negative regulation of blood pressure response to pain ion homeostasis response to corticosterone positive regulation of corticotropin secretion positive regulation of cortisol secretion long-term synaptic potentiation positive regulation of digestive system process negative regulation of cell death negative regulation of glucagon secretion cellular response to cocaine cellular response to dexamethasone stimulus positive regulation of calcium ion import regulation of N-methyl-D-aspartate selective glutamate receptor activity positive regulation of corticosterone secretion positive regulation of behavioral fear response steroid metabolic process response to cocaine
            It has to be done as per old AB suggested Products section.
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            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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