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Invitrogen
Cullin 4A Monoclonal Antibody (GT885)
Advanced Verification
This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 4
Cullin 4A Antibody (MA5-27796) in ICC/IF
Cullin 4A Monoclonal Antibody (GT885) detects Cullin 4a protein at nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Cullin 4a protein stained by Cullin 4A Monoclonal Antibody (GT885) (Product # MA5-27796) diluted at 1:200. Red: Phalloidin, a cytoskeleton marker, diluted at 1:100. Scale bar = 10 µm.
Product Details
MA5-27796
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
GT885
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of Human Cullin 4a. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2735158
Product Specific Information
Positive Control: HeLa^M
^M
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
CUL4A (Cullin 4A) is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNA damage-response proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CUL 4A; CUL-4A; Cul4a protein; Cullin-4A; MGC36573; MGC64071; OTTHUMP00000018753
Gene Aliases: CUL4A
UniProt ID: (Human) Q13619
Entrez Gene ID: (Human) 8451
G1/S transition of mitotic cell cycle
nucleotide-excision repair, DNA damage recognition
nucleotide-excision repair, DNA duplex unwinding
in utero embryonic development
transcription-coupled nucleotide-excision repair
nucleotide-excision repair, preincision complex stabilization
nucleotide-excision repair, preincision complex assembly
nucleotide-excision repair, DNA incision, 3'-to lesion
nucleotide-excision repair, DNA incision, 5'-to lesion
cellular response to DNA damage stimulus
cell cycle arrest
positive regulation of cell proliferation
negative regulation of cell proliferation
viral process
hemopoiesis
negative regulation of granulocyte differentiation
nucleotide-excision repair, DNA incision
somatic stem cell population maintenance
DNA damage response, detection of DNA damage
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of protein metabolic process
global genome nucleotide-excision repair
intrinsic apoptotic signaling pathway
positive regulation of G1/S transition of mitotic cell cycle
regulation of DNA damage checkpoint
regulation of nucleotide-excision repair
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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