Search Thermo Fisher Scientific
- Contact Us
- Quick Order
-
Don't have an account ? Create Account
Search Thermo Fisher Scientific
NeoBiotechnologies
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: aromatic compound inducible; aryl hydrocarbon hydroxylase; Cholesterol 25-hydroxylase; CYP1A1; CYPIA1; CYPIA2; Cytochrome P(3)450; Cytochrome P-448; Cytochrome P-450d; cytochrome P1-450; cytochrome P1-450, dioxin-inducible; Cytochrome P3 450; Cytochrome P450 1A1; Cytochrome P450 1A2; Cytochrome P450 4; cytochrome P450 family 1 subfamily a polypeptide 1; cytochrome P450 family 1 subfamily a polypeptide 2; Cytochrome P450 form 6; cytochrome P450 subfamily I (aromatic compound-inducible) member A1 (C6 form c) (C6 form c); Cytochrome P450 subfamily I (aromatic compound-inducible) member A2 (Q42 form d); cytochrome P450 subfamily I, polypeptide 1; cytochrome P450, 1a1; cytochrome P450, 1a1, aromatic compound inducible; cytochrome P450, 1a2; cytochrome P450, 1a2, aromatic compound inducible; cytochrome P450, family 1, subfamily A, polypeptide 1; cytochrome P450, family 1, subfamily A, polypeptide 2; cytochrome P450, subfamily I (aromatic compound-inducible), member A1 (C6, form c) (C6, form c); cytochrome P450, subfamily I (aromatic compound-inducible), member A2 (Q42, form d); cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1; cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 2; Cytochrome P450-C; Cytochrome P450-D; Cytochrome P450-P1; Cytochrome P450-P2; Cytochrome P450-P3; Cytochrome P450MT2; dioxin-inducible; dioxin-inducible P3-450; flavoprotein-linked monooxygenase; Hydroperoxy icosatetraenoate dehydratase; microsomal monooxygenase; P-448; P450 form 4; P450-D; P450form6; P450MT2; xenobiotic monooxygenase
Gene Aliases: AHH; AHRR; CP11; CP12; CYP1; Cyp1a-1; Cyp1a-2; CYP1A1; CYP1A2; Cyp45c; Cypc45c; CYPD45; CYPIA1; P-450d; P-450MC; P1-450; P3-450; P450(PA); P450-1; P450-3; P450-C; P450DX; RATCYPD45
UniProt ID: (Human) P04798, (Human) P05177, (Mouse) P00184, (Rat) P00185, (Mouse) P00186, (Rat) P04799
Entrez Gene ID: (Human) 1543, (Human) 1544, (Mouse) 13076, (Rat) 24296, (Mouse) 13077, (Rat) 24297
Molecular Function:
oxidoreductase
oxygenase
metabolite interconversion enzyme
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support