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            • Primary Antibodies ›
            • Cytokeratin 1 Antibodies

            Proteintech

            Cytokeratin 1 Polyclonal Antibody

            15 References
            View all (23) Cytokeratin 1 antibodies
            Datasheet
            Protocols
            Questions & Answers
            Catalog # 16848-1-AP
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            Price (USD)
            492.00
            150 µL
             
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            Datasheet
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            Cite Cytokeratin 1 Polyclonal Antibody

            • Antibody Testing Data (12)
            Application
            Cytokeratin 1 Antibody in Immunocytochemistry (ICC/IF)
            Group 53 Created with Sketch.

            FIGURE: 1 / 12

            Cytokeratin 1 Antibody (16848-1-AP) in ICC/IF

            Immunofluorescent analysis of A431 cells using 16848-1-AP (Cytokeratin 1-specific antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).
            View Product

            Cytokeratin 1 Antibody in Immunocytochemistry (ICC/IF)
            Cytokeratin 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Cytokeratin 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Cytokeratin 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Cytokeratin 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Cytokeratin 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Cytokeratin 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Cytokeratin 1 Antibody in Western Blot (WB)
            Cytokeratin 1 Antibody in Western Blot (WB)
            Cytokeratin 1 Antibody in Western Blot (WB)
            Cytokeratin 1 Antibody in Western Blot (WB)
            Cytokeratin 1 Antibody in Immunoprecipitation (IP)

            Product Details

            16848-1-AP

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:500-1:2,000
            View 8 publications 8 publications

            Immunohistochemistry (IHC)

            -
            View 2 publications 2 publications

            Immunohistochemistry (Paraffin) (IHC (P))

            1:20-1:200
            -

            Immunocytochemistry (ICC/IF)

            1:20-1:200
            View 5 publications 5 publications

            Immunoprecipitation (IP)

            0.5-4.0 µg
            -
            Product Specifications

            Species Reactivity

            Human, Mouse, Rat

            Published species

            Human

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            Peptide

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            0.35 mg/mL

            Purification

            Antigen affinity chromatography

            Storage buffer

            PBS, pH 7.3, with 50% glycerol

            Contains

            0.02% sodium azide

            Storage conditions

            -20°C

            Shipping conditions

            Wet ice (domestic); Dry ice (international)

            Product Specific Information

            This antibody is specifically against keratin I.

            Target Information

            Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between approximately40 kDa and approximately68 kDa and isoelectric pH between 4. 9 - 7. 8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            Bioinformatics

            Protein Aliases: 67 kDa cytokeratin; CK-1; cytokeratin 1; Cytokeratin-1; epidermolytic hyperkeratosis 1; Hair alpha protein; K1; keratin 1, type II; keratin 86; keratin complex 2, basic, gene 1; Keratin, type II cytoskeletal 1; Keratin-1; krt1 {ECO:0000250|UniProtKB:P04264}; type II keratin Kb1; Type-II keratin Kb1

            View more View less

            Gene Aliases: CK1; EHK; EHK1; EPPK; K1; Kb1; Krt-2.1; KRT1; KRT1A; Krt2-1; Krt86; KRTA; NEPPK

            View more View less

            UniProt ID: (Human) P86104, (Mouse) P04104, (Rat) Q6IMF3

            View more View less

            Entrez Gene ID: (Human) 3848, (Mouse) 16678, (Rat) 300250

            View more View less

            Function(s)

            receptor activity structural molecule activity protein binding carbohydrate binding molecular_function

            Process(es)

            complement activation, lectin pathway retina homeostasis response to oxidative stress fibrinolysis regulation of angiogenesis negative regulation of inflammatory response establishment of skin barrier biological_process
            It has to be done as per old AB suggested Products section.
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