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Cytokeratin 3 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the corneal epithelium with family member KRT12 and mutations in these genes have been associated with Meesmann's Corneal Dystrophy. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. (NCBI Gene description)
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Protein Aliases: 65 kDa cytokeratin; CK-3; cytokeratin 3; Cytokeratin-3; K3; keratin 3, type II; Keratin, type II cytoskeletal 3; Keratin-3; Type-II keratin Kb3
Gene Aliases: CK3; K3; KRT3
UniProt ID: (Human) P12035
Entrez Gene ID: (Human) 3850
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