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NeoBiotechnologies
Cytokeratin 6B (KRT6B) (Basal Cell Marker) Monoclonal Antibody (KRT6B/2116)
Product Details
3854-MSM1-P0
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
KRT6B/2116
Immunogen
Recombinant full-length human KRT6B protein
Conjugate
Unconjugated
Form
Liquid
Concentration
200 µg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
4°C, do not freeze
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CK-6B; cytokeratin 6B; Cytokeratin-6B; K6B; keratin 6B, type II; keratin complex 2, basic, gene 6b; keratin, epidermal, type II, K6B; Keratin, type II cytoskeletal 6B; keratin-6-beta; Keratin-6B; keratin-like 1 (a type II keratin sequence); mK6-beta; Type-II keratin Kb10
Gene Aliases: BB144589; CK-6B; CK6B; K6B; Krt2-6b; KRT6B; KRTL1; mK6[b]; PC2; PC4
UniProt ID: (Human) P04259
Entrez Gene ID: (Human) 3854, (Mouse) 16688
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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