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NeoBiotechnologies
Cytokeratin 7/17 Monoclonal Antibody (C-46)
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Product Details
MSM14-949-P0
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
C-46
Immunogen
Cytoskeletal preparation from HeLa cells (human cervical carcinoma cells)
Conjugate
Unconjugated
Form
Liquid
Concentration
200 µg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
4°C, do not freeze
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Does not react with Mouse, Rat, Ferret or Rabbit
Target Information
Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between ~40 kDa and ~68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 39.1; CK-17; CK-7; cytokeratin 7; Cytokeratin-17; Cytokeratin-7; K17; K7; keratin 17, type I; keratin 7, type II; keratin, 55K type II cytoskeletal; keratin, simple epithelial type I, K7; Keratin, type I cytoskeletal 17; Keratin, type II cytoskeletal 7; Keratin-17; Keratin-7; Sarcolectin; type II mesothelial keratin K7; Type-II keratin Kb7
Gene Aliases: 39.1; CK-17; CK7; K17; K2C7; K7; KRT17; KRT7; PC; PC2; PCHC1; SCL
UniProt ID: (Human) Q04695, (Bovine) A1L595, (Bovine) Q29S21, (Human) P08729
Entrez Gene ID: (Human) 3872, (Bovine) 281889, (Bovine) 535697, (Human) 3855
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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