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            • Primary Antibodies ›
            • D4-GDI Antibodies

            Invitrogen

            D4-GDI Polyclonal Antibody

            View all (16) D4-GDI antibodies
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            Cite D4-GDI Polyclonal Antibody

            • Antibody Testing Data (2)
            Application
            D4-GDI Antibody in Immunocytochemistry (ICC/IF)
            Group 53 Created with Sketch.

            FIGURE: 1 / 2

            D4-GDI Antibody (PA5-97469) in ICC/IF

            Immunofluorescent analysis of D4-GDI in HepG2 cells using a D4-GDI polyclonal antibody (Product # PA5-97469) at a dilution of 1:100. Alexa Fluor 488-congugated Goat Anti-Rabbit IgG(H+L) secondary antibody was used.
            View Product

            D4-GDI Antibody in Immunocytochemistry (ICC/IF)
            D4-GDI Antibody in Western Blot (WB)

            Product Details

            PA5-97469

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:500-1:5,000
            -

            Immunocytochemistry (ICC/IF)

            1:50-1:200
            -

            ELISA (ELISA)

            Assay-Dependent
            -
            Product Specifications

            Species Reactivity

            Human

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            Recombinant Human Rho GDP-dissociation inhibitor 2 protein (2-86AA)
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            3 mg/mL

            Purification

            Protein G

            Storage buffer

            PBS, pH 7.4, with 50% glycerol

            Contains

            0.03% ProClin 300

            Storage conditions

            -20°C or -80°C if preferred

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_2812085

            Target Information

            Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: d4 gdi; GDI LYGDI; Ly-GDI; Rho GDI 2; Rho GDP dissociation inhibitor (GDI) beta; Rho GDP-dissociation inhibitor 2; Rho-GDI beta

            View more View less

            Gene Aliases: ARHGDIB; D4; GDIA2; GDID4; Ly-GDI; LYGDI; RAP1GN1; RhoGDI2

            View more View less

            UniProt ID: (Human) P52566

            View more View less

            Entrez Gene ID: (Human) 397

            View more View less

            Function(s)

            GTPase activity Rho GDP-dissociation inhibitor activity GTPase activator activity protein binding Rac GTPase binding G-protein modulator

            Process(es)

            movement of cell or subcellular component negative regulation of cell adhesion multicellular organism development regulation of Rho protein signal transduction positive regulation of GTPase activity regulation of small GTPase mediated signal transduction cellular response to redox state negative regulation of trophoblast cell migration regulation of actin cytoskeleton reorganization
            It has to be done as per old AB suggested Products section.
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