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Immunogen sequence: MAEKTQKSVK IAPGAVVCVE SEIRGDVTIG PRTVIHPKAR IIAEAGPIVI GEGNLIEEQA LIINAYPDNI TPDTEDPEPK PMIIGTNNVF EVGCYSQAMK MGDNNVIESK AYVGRNVILT SGCIIGACCN LNTFEVIPEN TVIYGADCLR RVQTERPQPQ TLQLDFLMKI LPNYHHLKKT MKGSSTPVKN; Positive Samples: A-549, U-251MG, 22Rv1, Mouse brain, Mouse thymus; Cellular Location: Chromosome, Cytoplasm, centromere, cytoskeleton, kinetochore
The protein encoded by this gene contains an RGD (Arg-Gly-Asp) motif in the N-terminal region, which confers adhesive properties to macromolecular proteins like fibronectin. It shares a high degree of sequence similarity with the mouse homolog, which has been suggested to play a role in mitochondrial biogenesis. The exact biological function of this gene is not known. [provided by RefSeq, Jul 2008]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: dynactin 6; Dynactin subunit 6; Dynactin subunit p27; novel RGD-containing protein; p27 dynactin subunit; Protein WS-3; RGD containing protein
Gene Aliases: AU044699; DCTN6; p27; WS-3; WS3
UniProt ID: (Human) O00399, (Mouse) Q9WUB4
Entrez Gene ID: (Human) 10671, (Mouse) 22428
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