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Proteintech

DDDDK Tag Polyclonal Antibody

Name: DDDDK Tag Polyclonal Antibody
Brand: Proteintech
SKU: 20543-1-AP
Price: 492.0 USD
Availability: InStock

861 References

View all (114) DYKDDDDK Tag antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (4)

Application

DDDDK Tag Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 4

DDDDK Tag Antibody (20543-1-AP) in ICC/IF

Immunofluorescent analysis of Transfected HEK-293 cells using 20543-1-AP (Flag tag antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

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Product Details

20543-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:4,000

View 421 publications 421 publications

Immunohistochemistry (IHC)

Assay-dependent

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

1:10-1:100

View 63 publications 63 publications

Flow Cytometry (Flow)

Assay-dependent

View 6 publications 6 publications

Immunoprecipitation (IP)

Assay-dependent

View 201 publications 201 publications

ChIP assay (ChIP)

View 5 publications 5 publications

RNA Immunoprecipitation (RIP)

View 7 publications 7 publications

Miscellaneous PubMed (Misc)

View 23 publications 23 publications

Not applicable (N/A)

View 134 publications 134 publications

Product Specifications

Species Reactivity

Tag

Published species

Human, Mouse, Non-human primate, Tag

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

DDDDK Tag Fusion Protein Ag2329

Conjugate

Unconjugated

Form

Liquid

Concentration

0.24 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This antibody is a rabbit polyclonal antibody raised against the 3xDYKDDDDKT sequence and recognizes the (1x) and (3x) DYKDDDDK peptide and detects DDDDK-tagged proteins.

Target Information

DYKDDDDK tag, also known as FLAG tag, is a short peptide sequence that is commonly used as a protein tag to facilitate protein purification, detection, and localization. The tag consists of eight amino acids: Asp-Tyr-Lys-Asp-Asp-Asp-Asp-Lys. It is often fused to the N- or C-terminus of a protein of interest, allowing for easy identification and isolation of the protein using anti-FLAG antibodies. The DYKDDDDK tag is widely used in molecular biology and biochemistry research, and has been employed in various applications, such as protein-protein interaction studies, protein expression analysis, and protein localization studies. The FLAG tag structure has been optimized for compatibility with the proteins it is attached to, in that it is more hydrophilic than other common epitope tags and therefore less likely to denature or inactivate proteins to which it is appended. FLAG is a registered trademark of Merck KGaA, Darmstadt, Germany.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

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RIP-PEN-seq identifies a class of kink-turn RNAs as splicing regulators.

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Nucleophilic covalent ligand discovery for the cysteine redoxome.

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DNA methylation-mediated silencing of Neuronatin promotes hepatocellular carcinoma proliferation through the PI3K-Akt signaling pathway.

Life sciences

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Sun Jan 01 00:00:00 UTC 2023

YAP1 synergize with YY1 transcriptional co-repress DUSP1 to induce osimertinib resistant by activating the EGFR/MAPK pathway and abrogating autophagy in non-small cell lung cancer.

International journal of biological sciences

Ning Y,Zheng H,Yang Y,Zang H,Wang W,Zhan Y,Wang H,Luo J,Wen Q,Peng J,Xiang J,Fan S

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FAM117B promotes gastric cancer growth and drug resistance by targeting the KEAP1/NRF2 signaling pathway.

The Journal of clinical investigation

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Wed Feb 01 00:00:00 UTC 2023

DNA replication initiation factor RECQ4 possesses a role in antagonizing DNA replication initiation.

Nature communications

Xu X,Chang CW,Li M,Omabe K,Le N,Chen YH,Liang F,Liu Y

Sat Mar 04 00:00:00 UTC 2023

Macrophage DCLK1 promotes atherosclerosis via binding to IKKβ and inducing inflammatory responses.

EMBO molecular medicine

Huang Z,Shen S,Han X,Li W,Luo W,Lin L,Xu M,Wang Y,Huang W,Wu G,Liang G

Mon May 08 00:00:00 UTC 2023

Macrophage DCLK1 promotes atherosclerosis via binding to IKKβ and inducing inflammatory responses.

EMBO molecular medicine

Huang Z,Shen S,Han X,Li W,Luo W,Lin L,Xu M,Wang Y,Huang W,Wu G,Liang G

Mon May 08 00:00:00 UTC 2023

NKAP acts with HDAC3 to prevent R-loop associated genome instability.

Cell death and differentiation

Zhang X,Duan J,Li Y,Jin X,Wu C,Yang X,Lu W,Ge W

Sat Jul 01 00:00:00 UTC 2023

Complex interaction network revealed by mutation of human telomerase 'insertion in fingers' and essential N-terminal domains and the telomere protein TPP1.

The Journal of biological chemistry

Lambert-Lanteigne P,Young A,Autexier C

Wed Mar 01 00:00:00 UTC 2023

Blockage of PPARγ T166 phosphorylation enhances the inducibility of beige adipocytes and improves metabolic dysfunctions.

Cell death and differentiation

Yang N,Wang Y,Tian Q,Wang Q,Lu Y,Sun L,Wang S,Bei Y,Ji J,Zhou H,Yang W,Yao P,Zhu W,Sun L,Huang Z,Li X,Shen P

Wed Mar 01 00:00:00 UTC 2023

Epigenetically silenced lncRNA SNAI3-AS1 promotes ferroptosis in glioma via perturbing the m⁶A-dependent recognition of Nrf2 mRNA mediated by SND1.

Journal of experimental & clinical cancer research : CR

Zheng J,Zhang Q,Zhao Z,Qiu Y,Zhou Y,Wu Z,Jiang C,Wang X,Jiang X

Fri May 19 00:00:00 UTC 2023

RNF112-mediated FOXM1 ubiquitination suppresses the proliferation and invasion of gastric cancer.

JCI insight

Zhang S,Wang J,Hu W,He L,Tang Q,Li J,Jie M,Li X,Liu C,Ouyang Q,Yang S,Hu C

Thu Jun 08 00:00:00 UTC 2023

Chromatin Remodelling Molecule ARID1A Determines Metastatic Heterogeneity in Triple-Negative Breast Cancer by Competitively Binding to YAP.

Cancers

Wang Y,Chen X,Qiao X,Xie Y,Guo D,Li B,Cao J,Tao Z,Hu X

Tue Apr 25 00:00:00 UTC 2023

SERPINA5 may promote the development of preeclampsia by disruption of the uPA/uPAR pathway.

Translational research : the journal of laboratory and clinical medicine

Long Y,Zeng S,Gao F,Liu F,Zhang Y,Zhou C,Zhu C,Zhao X,Han M,Gan Q,Ye W,Zeng F,Song C,Jiang M,Lash GE,Yang H

Sun Jan 01 00:00:00 UTC 2023

EVL and MIM/MTSS1 regulate actin cytoskeletal remodeling to promote dendritic filopodia in neurons.

The Journal of cell biology

Parker SS,Ly KT,Grant AD,Sweetland J,Wang AM,Parker JD,Roman MR,Saboda K,Roe DJ,Padi M,Wolgemuth CW,Langlais P,Mouneimne G

Mon May 01 00:00:00 UTC 2023

Human Cytomegalovirus IE1 Impairs Neuronal Migration by Downregulating Connexin 43.

Journal of virology

Huang SN,Pan YT,Zhou YP,Wang XZ,Mei MJ,Yang B,Li D,Zeng WB,Cheng S,Sun JY,Cheng H,Zhao F,Luo MH

Wed May 31 00:00:00 UTC 2023

Human cytomegalovirus pUL97 upregulates SOCS3 expression via transcription factor RFX7 in neural progenitor cells.

PLoS pathogens

Wang XZ,Wen L,Zhou YP,Huang SN,Yang B,Cheng S,Zeng WB,Mei MJ,Sun JY,Jiang X,Cheng H,Luo MH

Wed Feb 01 00:00:00 UTC 2023

Dihydrotanshinone I preconditions myocardium against ischemic injury via PKM2 glutathionylation sensitive to ROS.

Acta pharmaceutica Sinica. B

Wu X,Liu L,Zheng Q,Ye H,Yang H,Hao H,Li P

Sun Jan 01 00:00:00 UTC 2023

Circular RNA ARHGAP5 inhibits cisplatin resistance in cervical squamous cell carcinoma by interacting with AUF1.

Cancer science

Deng S,Qian L,Liu L,Liu H,Xu Z,Liu Y,Wang Y,Chen L,Zhou Y

Sat Apr 01 00:00:00 UTC 2023

RNA-binding motif 4 promotes angiogenesis in HCC by selectively activating VEGF-A expression.

Pharmacological research

Han H,Lin T,Wang Z,Song J,Fang Z,Zhang J,You X,Du Y,Ye J,Zhou G

Sun Jan 01 00:00:00 UTC 2023

RNA-binding motif 4 promotes angiogenesis in HCC by selectively activating VEGF-A expression.

Pharmacological research

Han H,Lin T,Wang Z,Song J,Fang Z,Zhang J,You X,Du Y,Ye J,Zhou G

Sun Jan 01 00:00:00 UTC 2023

Dectin-1 plays a deleterious role in high fat diet-induced NAFLD of mice through enhancing macrophage activation.

Acta pharmacologica Sinica

Wang MX,Luo W,Ye L,Jin LM,Yang B,Zhang QH,Qian JC,Wang Y,Zhang Y,Liang G

Sun Jan 01 00:00:00 UTC 2023

Dectin-1 plays a deleterious role in high fat diet-induced NAFLD of mice through enhancing macrophage activation.

Acta pharmacologica Sinica

Wang MX,Luo W,Ye L,Jin LM,Yang B,Zhang QH,Qian JC,Wang Y,Zhang Y,Liang G

Sun Jan 01 00:00:00 UTC 2023

Oncolytic herpes simplex virus armed with a bacterial GBP1 degrader improves antitumor activity.

Molecular therapy oncolytics

Xie J,Wang S,Zhong Y,Gao M,Tian X,Zhang L,Pan D,Qin Q,Wu B,Lan K,Sun ZJ,Zhang J

Thu Jun 15 00:00:00 UTC 2023

Oncolytic herpes simplex virus armed with a bacterial GBP1 degrader improves antitumor activity.

Molecular therapy oncolytics

Xie J,Wang S,Zhong Y,Gao M,Tian X,Zhang L,Pan D,Qin Q,Wu B,Lan K,Sun ZJ,Zhang J

Thu Jun 15 00:00:00 UTC 2023

Oridonin ameliorates acetaminophen-induced acute liver injury through ATF4/PGC-1α pathway.

Drug development research

Yu D,Li J,Wang Y,Guo D,Zhang X,Chen M,Zhou Z

Sat Apr 01 00:00:00 UTC 2023

Iso-seco-tanapartholide induces p62 covalent oligomerization to activate KEAP1-NRF2 redox pathway in rheumatoid arthritis.

International immunopharmacology

Zhu D,Kong M,Chen C,Luo J,Kong L

Wed Feb 01 00:00:00 UTC 2023

Characterization and role of connective tissue growth factor gene in collagen synthesis in swim bladder of chu's croaker (Nibea coibor).

International journal of biological macromolecules

Lin F,Yuan Y,Ye X,Lv J,Liu X,Guo H,Wen X

Wed Feb 01 00:00:00 UTC 2023

The HIPK2/CDC14B-MeCP2 axis enhances the spindle assembly checkpoint block by promoting cyclin B translation.

Science advances

Partscht P,Simon A,Chen NP,Erhardt S,Schiebel E

Fri Jan 20 00:00:00 UTC 2023

EIF4A3-induced Circ_0001187 facilitates AML suppression through promoting ubiquitin-proteasomal degradation of METTL3 and decreasing m6A modification level mediated by miR-499a-5p/RNF113A pathway.

Biomarker research

Yang X,Han F,Hu X,Li G,Wu H,Can C,Wei Y,Liu J,Wang R,Jia W,Ji C,Ma D

Tue Jun 06 00:00:00 UTC 2023

FXR1 regulates vascular smooth muscle cell cytoskeleton, VSMC contractility, and blood pressure by multiple mechanisms.

Cell reports

St Paul A,Corbett C,Peluzzo A,Kelemen S,Okune R,Haines DS,Preston K,Eguchi S,Autieri MV

Tue Apr 25 00:00:00 UTC 2023

Berberine stimulates lysosomal AMPK independent of PEN2 and maintains cellular AMPK activity through inhibiting the dephosphorylation regulator UHRF1.

Frontiers in pharmacology

Ren G,Ding YW,Wang LL,Jiang JD

Sun May 07 00:00:00 UTC 2023

SARS-CoV-2 ORF3a positively regulates NF-κB activity by enhancing IKKβ-NEMO interaction.

Virus research

Nie Y,Mou L,Long Q,Deng D,Hu R,Cheng J,Wu J

Sat Apr 15 00:00:00 UTC 2023

Cathelicidin LL-37 promotes EMT, migration and metastasis of hepatocellular carcinoma cells in vitro and mouse model.

Cell adhesion & migration

Zhang H,Yuan X,Yang Y,Wanyan Y,Tao L,Chen Y

Fri Dec 01 00:00:00 UTC 2023

Sclareol attenuates liver fibrosis through SENP1-mediated VEGFR2 SUMOylation and inhibition of downstream STAT3 signaling.

Phytotherapy research : PTR

Ge MX,Niu WX,Bao YY,Lu ZN,He HW

Fri Sep 01 00:00:00 UTC 2023

EFHD1, a novel mitochondrial regulator of tumor metastasis in clear cell renal cell carcinoma.

Cancer science

Meng K,Hu Y,Wang D,Li Y,Shi F,Lu J,Wang Y,Cao Y,Zhang CZ,He QY

Mon May 01 00:00:00 UTC 2023

EFHD1, a novel mitochondrial regulator of tumor metastasis in clear cell renal cell carcinoma.

Cancer science

Meng K,Hu Y,Wang D,Li Y,Shi F,Lu J,Wang Y,Cao Y,Zhang CZ,He QY

Mon May 01 00:00:00 UTC 2023

Histone phosphorylation integrates the hepatic glucagon-PKA-CREB gluconeogenesis program in response to fasting.

Molecular cell

Zhao Y,Li S,Chen Y,Wang Y,Wei Y,Zhou T,Zhang Y,Yang Y,Chen L,Liu Y,Hu C,Zhou B,Ding Q

Thu Apr 06 00:00:00 UTC 2023

iASPP regulates neurite development by interacting with Spectrin proteins.

Frontiers in molecular neuroscience

Wang J,Jia C,Gao Q,Zhang J,Gu X

Thu Jun 08 00:00:00 UTC 2023

iASPP regulates neurite development by interacting with Spectrin proteins.

Frontiers in molecular neuroscience

Wang J,Jia C,Gao Q,Zhang J,Gu X

Thu Jun 08 00:00:00 UTC 2023

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

Cellular and molecular gastroenterology and hepatology

Yuan J,Lv T,Yang J,Wu Z,Yan L,Yang J,Shi Y,Jiang L

Thu Jan 26 00:00:00 UTC 2023

THOC5 complexes with DDX5, DDX17, and CDK12 to regulate R loop structures and transcription elongation rate.

iScience

Polenkowski M,Allister AB,Burbano de Lara S,Pierce A,Geary B,El Bounkari O,Wiehlmann L,Hoffmann A,Whetton AD,Tamura T,Tran DDH

Fri Jan 20 00:00:00 UTC 2023

The complement inhibitor CD59 is required for GABAergic synaptic transmission in the dentate gyrus.

Cell reports

Wen L,Yang X,Wu Z,Fu S,Zhan Y,Chen Z,Bi D,Shen Y

Tue Apr 25 00:00:00 UTC 2023

Decoding m⁶A RNA methylome identifies PRMT6-regulated lipid transport promoting AML stem cell maintenance.

Cell stem cell

Cheng Y,Gao Z,Zhang T,Wang Y,Xie X,Han G,Li Y,Yin R,Chen Y,Wang P,Hu J,Zhang T,Guo C,Chai J,Wang J,Cui M,Gao K,Liu W,Yao S,Lu P,Cao Z,Zheng Y,Chang J,Liu Z,Song Q,Li W,Zhou F,Zhang H

Thu Jan 05 00:00:00 UTC 2023

Tanshinone I specifically suppresses NLRP3 inflammasome activation by disrupting the association of NLRP3 and ASC.

Molecular medicine (Cambridge, Mass.)

Zhao J,Liu H,Hong Z,Luo W,Mu W,Hou X,Xu G,Fang Z,Ren L,Liu T,Wen J,Shi W,Wei Z,Yang Y,Zou W,Zhao J,Xiao X,Bai Z,Zhan X

Mon Jul 03 00:00:00 UTC 2023

Tanshinone I specifically suppresses NLRP3 inflammasome activation by disrupting the association of NLRP3 and ASC.

Molecular medicine (Cambridge, Mass.)

Zhao J,Liu H,Hong Z,Luo W,Mu W,Hou X,Xu G,Fang Z,Ren L,Liu T,Wen J,Shi W,Wei Z,Yang Y,Zou W,Zhao J,Xiao X,Bai Z,Zhan X

Mon Jul 03 00:00:00 UTC 2023

UBE2E2 enhances Snail-mediated epithelial-mesenchymal transition and Nrf2-mediated antioxidant activity in ovarian cancer.

Cell death & disease

Hong X,Ma N,Li D,Zhang M,Dong W,Huang J,Ci X,Zhang S

Fri Feb 10 00:00:00 UTC 2023

Comprehensive proteogenomic characterization of early duodenal cancer reveals the carcinogenesis tracks of different subtypes.

Nature communications

Li L,Jiang D,Liu H,Guo C,Zhao R,Zhang Q,Xu C,Qin Z,Feng J,Liu Y,Wang H,Chen W,Zhang X,Li B,Bai L,Tian S,Tan S,Yu Z,Chen L,Huang J,Zhao JY,Hou Y,Ding C

Wed Mar 29 00:00:00 UTC 2023

Comprehensive proteogenomic characterization of early duodenal cancer reveals the carcinogenesis tracks of different subtypes.

Nature communications

Li L,Jiang D,Liu H,Guo C,Zhao R,Zhang Q,Xu C,Qin Z,Feng J,Liu Y,Wang H,Chen W,Zhang X,Li B,Bai L,Tian S,Tan S,Yu Z,Chen L,Huang J,Zhao JY,Hou Y,Ding C

Wed Mar 29 00:00:00 UTC 2023

Insertion of exogenous genes within the ORF1b coding region of porcine astrovirus.

Veterinary microbiology

Liu T,Liao Y,Du Y,Dong Q,Zhang W,Qiao C,Chen Y,Ouyang K,Wei Z,Qin Y,Huang W

Mon May 01 00:00:00 UTC 2023

FEBS letters

Li J,Xu X,Liu J,Zhang S,Wang T,Liu Y,Wang Z

Thu Jun 01 00:00:00 UTC 2023

FEBS letters

Li J,Xu X,Liu J,Zhang S,Wang T,Liu Y,Wang Z

Thu Jun 01 00:00:00 UTC 2023

USP33 enhances cell survival and stemness by deubiquitinating CTNNB1 in BXPC-3 and SW1990 cells.

Cell biology international

Zhong B,Zhu Q,Wang L,Wang F,Zheng Y,Lin S,Cheng X

Tue Aug 01 00:00:00 UTC 2023

MTHFD2 reprograms macrophage polarization by inhibiting PTEN.

Cell reports

Shang M,Ni L,Shan X,Cui Y,Hu P,Ji Z,Shen L,Zhang Y,Zhou J,Wang T,Yu Q

Tue May 30 00:00:00 UTC 2023

MTHFD2 reprograms macrophage polarization by inhibiting PTEN.

Cell reports

Shang M,Ni L,Shan X,Cui Y,Hu P,Ji Z,Shen L,Zhang Y,Zhou J,Wang T,Yu Q

Tue May 30 00:00:00 UTC 2023

Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.

Nature metabolism

Yang Z,Yan C,Ma J,Peng P,Ren X,Cai S,Shen X,Wu Y,Zhang S,Wang X,Qiu S,Zhou J,Fan J,Huang H,Gao Q

Sun Jan 01 00:00:00 UTC 2023

Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.

Nature metabolism

Yang Z,Yan C,Ma J,Peng P,Ren X,Cai S,Shen X,Wu Y,Zhang S,Wang X,Qiu S,Zhou J,Fan J,Huang H,Gao Q

Sun Jan 01 00:00:00 UTC 2023

A novel variant in the FBP1 gene causes fructose-1,6-bisphosphatase deficiency through increased ubiquitination.

Archives of biochemistry and biophysics

Liang X,Liu X,Li W,Zhang L,Zhang B,Lai G,Zhao Y

Sat Jul 01 00:00:00 UTC 2023

Structural insights into pathogenic mechanism of hypohidrotic ectodermal dysplasia caused by ectodysplasin A variants.

Nature communications

Yu K,Huang C,Wan F,Jiang C,Chen J,Li X,Wang F,Wu J,Lei M,Wu Y

Sat Feb 11 00:00:00 UTC 2023

Up-regulated oxidized USP2a can increase Mdm2-p60-p53 to promote cell apoptosis.

Experimental cell research

Zhu H,Zhang H,Guo J,Zhang C,Zhang Q,Gao F

Thu Jun 01 00:00:00 UTC 2023

FOXM1 increases hTERT protein stability and indicates poor prognosis in gastric cancer.

Neoplasia (New York, N.Y.)

Tang Q,Liu C,Zhang S,He L,Liu Y,Wang J,Zhao X,Li X

Wed Feb 01 00:00:00 UTC 2023

African swine fever virus pA104R protein acts as a suppressor of type I interferon signaling.

Frontiers in microbiology

Chen Q,Li L,Guo S,Liu Z,Liu L,Tan C,Chen H,Wang X

Tue Apr 25 00:00:00 UTC 2023

Upregulation of galectin-3 in influenza A virus infection promotes viral RNA synthesis through its association with viral PA protein.

Journal of biomedical science

Yang ML,Chen YC,Wang CT,Chong HE,Chung NH,Leu CH,Liu FT,Lai MMC,Ling P,Wu CL,Shiau AL

Thu Feb 23 00:00:00 UTC 2023

The moonlighting function of glycolytic enzyme enolase-1 promotes choline phospholipid metabolism and tumor cell proliferation.

Proceedings of the National Academy of Sciences of the United States of America

Ma Q,Jiang H,Ma L,Zhao G,Xu Q,Guo D,He N,Liu H,Meng Z,Liu J,Zhu L,Lin Q,Wu X,Li M,Luo S,Fang J,Lu Z

Tue Apr 11 00:00:00 UTC 2023

The moonlighting function of glycolytic enzyme enolase-1 promotes choline phospholipid metabolism and tumor cell proliferation.

Proceedings of the National Academy of Sciences of the United States of America

Ma Q,Jiang H,Ma L,Zhao G,Xu Q,Guo D,He N,Liu H,Meng Z,Liu J,Zhu L,Lin Q,Wu X,Li M,Luo S,Fang J,Lu Z

Tue Apr 11 00:00:00 UTC 2023

Ly6D facilitates chemoresistance in laryngeal squamous cell carcinoma through miR-509/β-catenin signaling pathway.

American journal of cancer research

Wang J,Sheng N,Li Y,Fan Y,Nan X,Fu R

Mon Jun 12 00:00:00 UTC 2023

The hTERT-p50 homodimer inhibits PLEKHA7 expression to promote gastric cancer invasion and metastasis.

Oncogene

Wu YY,Xiao YF,Tian LX,He B,Liu J,Li ZB,Yang H,Chen Y,Luo Q,Li BS,Yang SM

Wed Mar 01 00:00:00 UTC 2023

MPC2 variants disrupt mitochondrial pyruvate metabolism and cause an early-onset mitochondriopathy.

Brain : a journal of neurology

Pujol C,Lebigot E,Gaignard P,Galai S,Kraoua I,Bault JP,Dard R,Youssef-Turki IB,Omar S,Boutron A,Wai T,Slama A

Wed Mar 01 00:00:00 UTC 2023

MPC2 variants disrupt mitochondrial pyruvate metabolism and cause an early-onset mitochondriopathy.

Brain : a journal of neurology

Pujol C,Lebigot E,Gaignard P,Galai S,Kraoua I,Bault JP,Dard R,Youssef-Turki IB,Omar S,Boutron A,Wai T,Slama A

Wed Mar 01 00:00:00 UTC 2023

Hypoxia-induced GPCPD1 depalmitoylation triggers mitophagy via regulating PRKN-mediated ubiquitination of VDAC1.

Autophagy

Liu Y,Zhang H,Liu Y,Zhang S,Su P,Wang L,Li Y,Liang Y,Wang X,Zhao W,Chen B,Luo D,Zhang N,Yang Q

Fri Sep 01 00:00:00 UTC 2023

Hypoxia-induced GPCPD1 depalmitoylation triggers mitophagy via regulating PRKN-mediated ubiquitination of VDAC1.

Autophagy

Liu Y,Zhang H,Liu Y,Zhang S,Su P,Wang L,Li Y,Liang Y,Wang X,Zhao W,Chen B,Luo D,Zhang N,Yang Q

Fri Sep 01 00:00:00 UTC 2023

ZDHHC2-Mediated AGK Palmitoylation Activates AKT-mTOR Signaling to Reduce Sunitinib Sensitivity in Renal Cell Carcinoma.

Cancer research

Sun Y,Zhu L,Liu P,Zhang H,Guo F,Jin X

Thu Jun 15 00:00:00 UTC 2023

ZDHHC2-Mediated AGK Palmitoylation Activates AKT-mTOR Signaling to Reduce Sunitinib Sensitivity in Renal Cell Carcinoma.

Cancer research

Sun Y,Zhu L,Liu P,Zhang H,Guo F,Jin X

Thu Jun 15 00:00:00 UTC 2023

The zinc figure protein ZNF575 impairs colorectal cancer growth via promoting p53 transcription.

Oncology research

An N,Peng H,Hou M,Su D,Wang L,Shen X,Zhang M

Mon Jan 22 00:00:00 UTC 2024

Plasma membrane-associated calcium signaling regulates arsenate tolerance in Arabidopsis.

Plant physiology

Liu Y,Zhang Y,Wang Z,Guo S,Fang Y,Zhang Z,Gao H,Ren H,Wang C

Wed May 31 00:00:00 UTC 2023

Coordinated histone variant H2A.Z eviction and H3.3 deposition control plant thermomorphogenesis.

The New phytologist

Zhao F,Xue M,Zhang H,Li H,Zhao T,Jiang D

Sat Apr 01 00:00:00 UTC 2023

LIM domain-containing protein Ajuba inhibits chemotherapy-induced apoptosis by negatively regulating p53 stability in colorectal cancer cells.

Molecular oncology

Xu B,Li Q,Zhang J,Chen F

Tue Aug 01 00:00:00 UTC 2023

LIM domain-containing protein Ajuba inhibits chemotherapy-induced apoptosis by negatively regulating p53 stability in colorectal cancer cells.

Molecular oncology

Xu B,Li Q,Zhang J,Chen F

Tue Aug 01 00:00:00 UTC 2023

Short-Term Starvation Weakens the Efficacy of Cell Cycle Specific Chemotherapy Drugs through G1 Arrest.

International journal of molecular sciences

Shi M,Hou J,Shao S,Liang W,Wang S,Yang Y,Guo Z,Pan F

Sat Jan 28 00:00:00 UTC 2023

Effects of Spatial Expression of Activating Transcription Factor 4 on the Pathogenicity of Two Phenotypes of Bovine Viral Diarrhea Virus by Regulating the Endoplasmic Reticulum-Mediated Autophagy Process.

Microbiology spectrum

Wang J,Chen KY,Wang SH,Liu Y,Zhao YQ,Yang L,Yang GH,Wang XJ,Zhu YH,Yin JH,Wang JF

Mon Mar 20 00:00:00 UTC 2023

Microbiology spectrum

Wang J,Chen KY,Wang SH,Liu Y,Zhao YQ,Yang L,Yang GH,Wang XJ,Zhu YH,Yin JH,Wang JF

Mon Mar 20 00:00:00 UTC 2023

Clinical Implications of a New DDX58 Pathogenic Variant That Causes Lupus Nephritis due to RIG-I Hyperactivation.

Journal of the American Society of Nephrology : JASN

Peng J,Wang Y,Han X,Zhang C,Chen X,Jin Y,Yang Z,An Y,Zhang J,Liu Z,Chen Y,Gao E,Zhang Y,Xu F,Zheng C,Zhou Q,Liu Z

Wed Feb 01 00:00:00 UTC 2023

Connexin32 Promotes the Activation of Foxo3a to Ameliorate Diabetic Nephropathy via Inhibiting the Polyubiquitination and Degradation of Sirt1.

Antioxidants & redox signaling

Li S,Xiao H,Sun X,Chen Z,Lin Z,Li C,Zeng J,Xu Z,Cheng Y,Huang H

Tue Aug 01 00:00:00 UTC 2023

Profiling of N6-methyladenosine methylation in porcine longissimus dorsi muscle and unravelling the hub gene ADIPOQ promotes adipogenesis in an m⁶A-YTHDF1-dependent manner.

Journal of animal science and biotechnology

Gong H,Gong T,Liu Y,Wang Y,Wang X

Thu Apr 06 00:00:00 UTC 2023

Fyn deficiency inhibits oxidative stress by decreasing c-Cbl-mediated ubiquitination of Sirt1 to attenuate diabetic renal fibrosis.

Metabolism: clinical and experimental

Li S,Lin Z,Xiao H,Xu Z,Li C,Zeng J,Xie X,Deng L,Huang H

Wed Feb 01 00:00:00 UTC 2023

PACT inhibits the replication of SARS-CoV-2 through the blockage of GSK-3β-N-nsp3 cascade.

Journal of medical virology

Lin YY,Yao R,Zhuang J,Wang B,Du L,Guo D,Pan JA,Peng X

Thu Jun 01 00:00:00 UTC 2023

PACT inhibits the replication of SARS-CoV-2 through the blockage of GSK-3β-N-nsp3 cascade.

Journal of medical virology

Lin YY,Yao R,Zhuang J,Wang B,Du L,Guo D,Pan JA,Peng X

Thu Jun 01 00:00:00 UTC 2023

PACT inhibits the replication of SARS-CoV-2 through the blockage of GSK-3β-N-nsp3 cascade.

Journal of medical virology

Lin YY,Yao R,Zhuang J,Wang B,Du L,Guo D,Pan JA,Peng X

Thu Jun 01 00:00:00 UTC 2023

N⁶-methyladenosine of Spi2a attenuates inflammation and sepsis-associated myocardial dysfunction in mice.

Nature communications

Wang X,Ding Y,Li R,Zhang R,Ge X,Gao R,Wang M,Huang Y,Zhang F,Zhao B,Liao W,Du J

Thu Mar 02 00:00:00 UTC 2023

Tanshinone IIA analogue 15a inhibits NLRP3-mediated inflammation by activating mitophagy in macrophages to alleviate acute tubular necrosis.

International immunopharmacology

Chen J,Luo W,Hu C,Ren M,Xu H,Xu X,Li W,Chen Y,Shao J,Xiao Z,Lv X,Liang G

Mon May 01 00:00:00 UTC 2023

Tanshinone IIA analogue 15a inhibits NLRP3-mediated inflammation by activating mitophagy in macrophages to alleviate acute tubular necrosis.

International immunopharmacology

Chen J,Luo W,Hu C,Ren M,Xu H,Xu X,Li W,Chen Y,Shao J,Xiao Z,Lv X,Liang G

Mon May 01 00:00:00 UTC 2023

Clinical heterogeneity of NLRP12-associated autoinflammatory diseases.

Genes & diseases

Li Y,Deng M,Li Y,Mao X,Yan S,Tang X,Mao H

Mon May 01 00:00:00 UTC 2023

Anisomycin inhibits Coxsackievirus B replication by promoting the lysosomal degradation of eEF1A1.

Antiviral research

Shao E,Zhao S,Dong Y,Wang Y,Fei Y,Li S,Wang L,Bashir T,Luan T,Lin L,Wang Y,Zhao W,Zhong Z

Sat Jul 01 00:00:00 UTC 2023

FAAH served a key membrane-anchoring and stabilizing role for NLRP3 protein independently of the endocannabinoid system.

Cell death and differentiation

Zhu Y,Zhang H,Mao H,Zhong S,Huang Y,Chen S,Yan K,Zhao Z,Hao X,Zhang Y,Yao H,Huang X,Wang M,Zhang W,Li J,Meng G,Qin X,Ye Z,Shen J,Song Y,Xu Y,Yang Z,Wang L,Zhang Y,Wen L

Sun Jan 01 00:00:00 UTC 2023

An early-onset SLE patient with a novel paternal inherited BACH2 mutation.

Journal of clinical immunology

Zhou L,Sun G,Chen R,Chen J,Fang S,Xu Q,Tang W,Dai R,Zhang Z,An Y,Tang X,Zhao X

Tue Aug 01 00:00:00 UTC 2023

FAM210A Regulates Mitochondrial Translation and Maintains Cardiac Mitochondrial Homeostasis.

bioRxiv : the preprint server for biology

Wu J,Subbaiah KCV,Hedaya O,Chen S,Munger J,Tang WHW,Yan C,Yao P

Mon May 22 00:00:00 UTC 2023

The G allele of SNP rs3922 reduces the binding affinity between IGF2BP3 and CXCR5 correlating with a lower antibody production.

European journal of immunology

Duan Z,Ma L,Jin J,Ma L,Ye L,Wu J,Luo Y

Tue Aug 01 00:00:00 UTC 2023

Promotion of intestinal epithelial cell apoptosis by enterotoxigenic Escherichia coli via PKA-mediated inhibition of mTORC1 activation.

Microbes and infection

Zheng Y,Wang G,Li R,Geng H,Lei X,Chen L,Wu S,Yao J,Deng L

Thu Jun 01 00:00:00 UTC 2023

A novel missense variant c.71G > T (p.Gly24Val) of the CRYBA4 gene contributes to autosomal-dominant congenital cataract in a Chinese family.

International ophthalmology

Zhang X,Liang C,Liu M,Wang Z,Leng X,Xie S,Tan X,Yang Y,Liu Y

Sun Jan 01 00:00:00 UTC 2023

Gasdermin D affects aortic vascular smooth muscle cell pyroptosis and Ang II-induced vascular remodeling.

Heliyon

Fang Z,Wu G,Sheng J,Ye B,Huang Z,Xu J,Zhang J,Han J,Han B,Xu J

Thu Jun 01 00:00:00 UTC 2023

CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1.

Oncogene

Li D,Wang Y,Dong C,Chen T,Dong A,Ren J,Li W,Shu G,Yang J,Shen W,Qin L,Hu L,Zhou J

Sun Jan 01 00:00:00 UTC 2023

CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1.

Oncogene

Li D,Wang Y,Dong C,Chen T,Dong A,Ren J,Li W,Shu G,Yang J,Shen W,Qin L,Hu L,Zhou J

Sun Jan 01 00:00:00 UTC 2023

CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1.

Oncogene

Li D,Wang Y,Dong C,Chen T,Dong A,Ren J,Li W,Shu G,Yang J,Shen W,Qin L,Hu L,Zhou J

Sun Jan 01 00:00:00 UTC 2023

CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1.

Oncogene

Li D,Wang Y,Dong C,Chen T,Dong A,Ren J,Li W,Shu G,Yang J,Shen W,Qin L,Hu L,Zhou J

Sun Jan 01 00:00:00 UTC 2023

MTAP-ANRIL gene fusion promotes melanoma epithelial-mesenchymal transition-like process by activating the JNK and p38 signaling pathways.

Scientific reports

Lin Z,Lei Y,Wen M,He Q,Tian D,Xie H

Mon Jun 05 00:00:00 UTC 2023

A restrictor complex of ZC3H4, WDR82, and ARS2 integrates with PNUTS to control unproductive transcription.

Molecular cell

Estell C,Davidson L,Eaton JD,Kimura H,Gold VAM,West S

Thu Jul 06 00:00:00 UTC 2023

Turnip crinkle virus-encoded suppressor of RNA silencing interacts with Arabidopsis SGS3 to enhance virus infection.

Molecular plant pathology

Liu L,Wang H,Fu Y,Tang W,Zhao P,Ren Y,Liu Z,Wu K,Zhang X

Wed Feb 01 00:00:00 UTC 2023

OTUD1 promotes pathological cardiac remodeling and heart failure by targeting STAT3 in cardiomyocytes.

Theranostics

Wang M,Han X,Yu T,Wang M,Luo W,Zou C,Li X,Li G,Wu G,Wang Y,Liang G

Fri May 12 00:00:00 UTC 2023

OTUD1 promotes pathological cardiac remodeling and heart failure by targeting STAT3 in cardiomyocytes.

Theranostics

Wang M,Han X,Yu T,Wang M,Luo W,Zou C,Li X,Li G,Wu G,Wang Y,Liang G

Fri May 12 00:00:00 UTC 2023

RNF8 enhances the sensitivity of PD-L1 inhibitor against melanoma through ubiquitination of galectin-3 in stroma.

Cell death discovery

Guo Y,Shen R,Yang K,Wang Y,Song H,Liu X,Cheng X,Wu R,Song Y,Wang D

Fri Jun 30 00:00:00 UTC 2023

RNF8 enhances the sensitivity of PD-L1 inhibitor against melanoma through ubiquitination of galectin-3 in stroma.

Cell death discovery

Guo Y,Shen R,Yang K,Wang Y,Song H,Liu X,Cheng X,Wu R,Song Y,Wang D

Fri Jun 30 00:00:00 UTC 2023

p38-mediated FOXN3 phosphorylation modulates lung inflammation and injury through the NF-κB signaling pathway.

Nucleic acids research

Zhu X,Huang B,Zhao F,Lian J,He L,Zhang Y,Ji L,Zhang J,Yan X,Zeng T,Ma C,Liang Y,Zhang C,Lin J

Tue Mar 21 00:00:00 UTC 2023

Flavivirus prM interacts with MDA5 and MAVS to inhibit RLR antiviral signaling.

Cell & bioscience

Sui L,Zhao Y,Wang W,Chi H,Tian T,Wu P,Zhang J,Zhao Y,Wei ZK,Hou Z,Zhou G,Wang G,Wang Z,Liu Q

Fri Jan 13 00:00:00 UTC 2023

Rift Valley Fever Virus Nucleoprotein Triggers Autophagy to Dampen Antiviral Innate Immune Responses.

Journal of virology

Zhu X,Guan Z,Fang Y,Zhang Y,Guan Z,Li S,Peng K

Thu Apr 27 00:00:00 UTC 2023

Rift Valley Fever Virus Nucleoprotein Triggers Autophagy to Dampen Antiviral Innate Immune Responses.

Journal of virology

Zhu X,Guan Z,Fang Y,Zhang Y,Guan Z,Li S,Peng K

Thu Apr 27 00:00:00 UTC 2023

A dual-regulation inducible switch system for microRNA detection and cell type-specific gene activation.

Theranostics

Shu WJ,Lee K,Ma Z,Tian X,Kim JS,Wang F

Wed May 24 00:00:00 UTC 2023

The deubiquitinase OTUD1 noncanonically suppresses Akt activation through its N-terminal intrinsically disordered region.

Cell reports

Fan G,Wang F,Chen Y,Zheng Q,Xiong J,Lv Q,Wu K,Xiong J,Wei L,Li D,Zhang J,Zhang W,Li F

Tue Jan 31 00:00:00 UTC 2023

Tabersonine, a natural NLRP3 inhibitor, suppresses inflammasome activation in macrophages and attenuate NLRP3-driven diseases in mice.

Acta pharmacologica Sinica

Xu HW,Li WF,Hong SS,Shao JJ,Chen JH,Chattipakorn N,Wu D,Luo W,Liang G

Thu Jun 01 00:00:00 UTC 2023

Tabersonine, a natural NLRP3 inhibitor, suppresses inflammasome activation in macrophages and attenuate NLRP3-driven diseases in mice.

Acta pharmacologica Sinica

Xu HW,Li WF,Hong SS,Shao JJ,Chen JH,Chattipakorn N,Wu D,Luo W,Liang G

Thu Jun 01 00:00:00 UTC 2023

SARS-CoV-2 Nsp8 induces mitophagy by damaging mitochondria.

Virologica Sinica

Zong S,Wu Y,Li W,You Q,Peng Q,Wang C,Wan P,Bai T,Ma Y,Sun B,Qiao J

Tue Aug 01 00:00:00 UTC 2023

SARS-CoV-2 Nsp8 induces mitophagy by damaging mitochondria.

Virologica Sinica

Zong S,Wu Y,Li W,You Q,Peng Q,Wang C,Wan P,Bai T,Ma Y,Sun B,Qiao J

Tue Aug 01 00:00:00 UTC 2023

SARS-CoV-2 Nsp8 induces mitophagy by damaging mitochondria.

Virologica Sinica

Zong S,Wu Y,Li W,You Q,Peng Q,Wang C,Wan P,Bai T,Ma Y,Sun B,Qiao J

Tue Aug 01 00:00:00 UTC 2023

SARS-CoV-2 Nsp8 induces mitophagy by damaging mitochondria.

Virologica Sinica

Zong S,Wu Y,Li W,You Q,Peng Q,Wang C,Wan P,Bai T,Ma Y,Sun B,Qiao J

Tue Aug 01 00:00:00 UTC 2023

Sec13 promotes oligodendrocyte differentiation and myelin repair through autocrine pleiotrophin signaling.

The Journal of clinical investigation

Liu Z,Yan M,Lei W,Jiang R,Dai W,Chen J,Wang C,Li L,Wu M,Nian X,Li D,Sun D,Lv X,Wang C,Xie C,Yao L,Wu C,Hu J,Xiao N,Mo W,Wang Z,Zhang L

Fri Apr 01 00:00:00 UTC 2022

OTUB2 regulates KRT80 stability via deubiquitination and promotes tumour proliferation in gastric cancer.

Cell death discovery

Ouyang S,Zeng Z,Liu Z,Zhang Z,Sun J,Wang X,Ma M,Ye X,Yu J,Kang W

Wed Feb 02 00:00:00 UTC 2022

OTUB2 regulates KRT80 stability via deubiquitination and promotes tumour proliferation in gastric cancer.

Cell death discovery

Ouyang S,Zeng Z,Liu Z,Zhang Z,Sun J,Wang X,Ma M,Ye X,Yu J,Kang W

Wed Feb 02 00:00:00 UTC 2022

Alternative splicing of HSPA12A pre-RNA by SRSF11 contributes to metastasis potential of colorectal cancer.

Clinical and translational medicine

Pan YJ,Huo FC,Kang MJ,Liu BW,Wu MD,Pei DS

Tue Nov 01 00:00:00 UTC 2022

Alternative splicing of HSPA12A pre-RNA by SRSF11 contributes to metastasis potential of colorectal cancer.

Clinical and translational medicine

Pan YJ,Huo FC,Kang MJ,Liu BW,Wu MD,Pei DS

Tue Nov 01 00:00:00 UTC 2022

Alternative splicing of HSPA12A pre-RNA by SRSF11 contributes to metastasis potential of colorectal cancer.

Clinical and translational medicine

Pan YJ,Huo FC,Kang MJ,Liu BW,Wu MD,Pei DS

Tue Nov 01 00:00:00 UTC 2022

USF1-ATRAP-PBX3 Axis Promote Breast Cancer Glycolysis and Malignant Phenotype by Activating AKT/mTOR Signaling.

International journal of biological sciences

Wang D,Jin X,Lei M,Jiang Y,Liu Y,Yu F,Guo Y,Han B,Yang Y,Sun W,Liu Y,Zeng G,Liu F,Hu J,Chen X

Thu Apr 14 00:00:00 UTC 2022

HMGB3 promotes PARP inhibitor resistance through interacting with PARP1 in ovarian cancer.

Cell death & disease

Ma H,Qi G,Han F,Lu W,Peng J,Li R,Yan S,Yuan C,Kong B

Thu Mar 24 00:00:00 UTC 2022

RBCK1 regulates the progression of ER-positive breast cancer through the HIF1α signaling.

Cell death & disease

Niu Z,Fan J,Chen F,Yang H,Li X,Zhuang T,Guo C,Cao Q,Zhu J,Wang H,Huang Q

Tue Dec 06 00:00:00 UTC 2022

E3 Ligase FBXW7 Facilitates Mycobacterium Immune Evasion by Modulating TNF-α Expression.

Frontiers in cellular and infection microbiology

Song J,Chao J,Hu X,Wen X,Ding C,Li D,Zhang D,Han S,Yu X,Yan B,Jin Z,Song Y,Gonzales J,Via LE,Zhang L,Wang D

Fri Jun 03 00:00:00 UTC 2022

HERC3 regulates epithelial-mesenchymal transition by directly ubiquitination degradation EIF5A2 and inhibits metastasis of colorectal cancer.

Cell death & disease

Zhang Z,He G,Lv Y,Liu Y,Niu Z,Feng Q,Hu R,Xu J

Fri Jan 21 00:00:00 UTC 2022

The "LLQY" Motif on SARS-CoV-2 Spike Protein Affects S Incorporation into Virus Particles.

Journal of virology

Du S,Xu W,Wang Y,Li L,Hao P,Tian M,Wang M,Li T,Wu S,Liu Q,Bai J,Qu X,Jin N,Zhou B,Liao M,Li C

Wed Mar 23 00:00:00 UTC 2022

IQGAP1 is positively correlated with PD-L1 and regulates its expression via mediating STAT proteins phosphorylation.

International immunopharmacology

Chen Y,Mei J,Zhang P,Liu J,Chen L,Wu L,Zhang Y

Fri Jul 01 00:00:00 UTC 2022

Structural basis for cytoplasmic dynein-1 regulation by Lis1.

eLife

Gillies JP,Reimer JM,Karasmanis EP,Lahiri I,Htet ZM,Leschziner AE,Reck-Peterson SL

Fri Jan 07 00:00:00 UTC 2022

Structural basis for cytoplasmic dynein-1 regulation by Lis1.

eLife

Gillies JP,Reimer JM,Karasmanis EP,Lahiri I,Htet ZM,Leschziner AE,Reck-Peterson SL

Fri Jan 07 00:00:00 UTC 2022

Natural variation in Glume Coverage 1 causes naked grains in sorghum.

Nature communications

Xie P,Tang S,Chen C,Zhang H,Yu F,Li C,Wei H,Sui Y,Wu C,Diao X,Wu Y,Xie Q

Fri Feb 25 00:00:00 UTC 2022

PSMA1 mediates tumor progression and poor prognosis of gastric carcinoma by deubiquitinating and stabilizing TAZ.

Cell death & disease

Yang Q,Lu Y,Shangguan J,Shu X

Wed Nov 23 00:00:00 UTC 2022

Structural basis of Tom20 and Tom22 cytosolic domains as the human TOM complex receptors.

Proceedings of the National Academy of Sciences of the United States of America

Su J,Liu D,Yang F,Zuo MQ,Li C,Dong MQ,Sun S,Sui SF

Tue Jun 28 00:00:00 UTC 2022

MICALL2 as a substrate of ubiquitinase TRIM21 regulates tumorigenesis of colorectal cancer.

Cell communication and signaling : CCS

Wen P,Wang H,Li Y,Sui X,Hou Z,Guo X,Xue W,Liu D,Wang Y,Gao J

Fri Oct 28 00:00:00 UTC 2022

MICALL2 as a substrate of ubiquitinase TRIM21 regulates tumorigenesis of colorectal cancer.

Cell communication and signaling : CCS

Wen P,Wang H,Li Y,Sui X,Hou Z,Guo X,Xue W,Liu D,Wang Y,Gao J

Fri Oct 28 00:00:00 UTC 2022

Antioxidant enzyme peroxiredoxin 5 regulates cyst growth and ciliogenesis via modulating Plk1 stability.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Agborbesong E,Zhou JX,Li LX,Calvet JP,Li X

Sat Jan 01 00:00:00 UTC 2022

lncRNA HITT Inhibits Lactate Production by Repressing PKM2 Oligomerization to Reduce Tumor Growth and Macrophage Polarization.

Research (Washington, D.C.)

Zhao K,Wang X,Zhao D,Lin Q,Zhang Y,Hu Y

Tue Aug 02 00:00:00 UTC 2022

SHLD1 is dispensable for 53BP1-dependent V(D)J recombination but critical for productive class switch recombination.

Nature communications

Vincendeau E,Wei W,Zhang X,Planchais C,Yu W,Lenden-Hasse H,Cokelaer T,Pipoli da Fonseca J,Mouquet H,Adams DJ,Alt FW,Jackson SP,Balmus G,Lescale C,Deriano L

Tue Jun 28 00:00:00 UTC 2022

TRX2/Rab35 Interaction Impairs Exosome Secretion by Inducing Rab35 Degradation.

International journal of molecular sciences

Zhang T,Zhao L,Han L,Li Y,Hu L,Wang H,Zou F

Sun Jun 12 00:00:00 UTC 2022

TRX2/Rab35 Interaction Impairs Exosome Secretion by Inducing Rab35 Degradation.

International journal of molecular sciences

Zhang T,Zhao L,Han L,Li Y,Hu L,Wang H,Zou F

Sun Jun 12 00:00:00 UTC 2022

ARNO is recruited by the neuronal adaptor FE65 to potentiate ARF6-mediated neurite outgrowth.

Open biology

Zhai Y,Chan WWR,Li W,Lau KF

Thu Sep 01 00:00:00 UTC 2022

Small Molecules Promote Selective Denaturation and Degradation of Tubulin Heterodimers through a Low-Barrier Hydrogen Bond.

Journal of medicinal chemistry

Yang J,Li Y,Qiu Q,Wang R,Yan W,Yu Y,Niu L,Pei H,Wei H,Ouyang L,Ye H,Xu D,Wei Y,Chen Q,Chen L

Thu Jul 14 00:00:00 UTC 2022

Bioactive Vitamin D Attenuates MED28-Mediated Cell Growth and Epithelial-Mesenchymal Transition in Human Colorectal Cancer Cells.

BioMed research international

Huang CY,Weng YT,Hsieh NT,Li PC,Lee TY,Li CI,Liu HS,Lee MF

Fri Sep 09 00:00:00 UTC 2022

CXCL12/CXCR7/β-arrestin1 biased signal promotes epithelial-to-mesenchymal transition of colorectal cancer by repressing miRNAs through YAP1 nuclear translocation.

Cell & bioscience

Si M,Song Y,Wang X,Wang D,Liu X,Qu X,Song Z,Yu X

Sun Oct 09 00:00:00 UTC 2022

CXCL12/CXCR7/β-arrestin1 biased signal promotes epithelial-to-mesenchymal transition of colorectal cancer by repressing miRNAs through YAP1 nuclear translocation.

Cell & bioscience

Si M,Song Y,Wang X,Wang D,Liu X,Qu X,Song Z,Yu X

Sun Oct 09 00:00:00 UTC 2022

TENT5 cytoplasmic noncanonical poly(A) polymerases regulate the innate immune response in animals.

Science advances

Liudkovska V,Krawczyk PS,Brouze A,Gumińska N,Wegierski T,Cysewski D,Mackiewicz Z,Ewbank JJ,Drabikowski K,Mroczek S,Dziembowski A

Fri Nov 18 00:00:00 UTC 2022

PIKE-A Modulates Mitochondrial Metabolism through Increasing SDHA Expression Mediated by STAT3/FTO Axis.

International journal of molecular sciences

Sun M,Yan Q,Qiao Y,Zhao H,Wang Y,Shan C,Zhang S

Sun Sep 25 00:00:00 UTC 2022

Inhibition of the lncRNA MIAT prevents podocyte injury and mitotic catastrophe in diabetic nephropathy.

Molecular therapy. Nucleic acids

Wang Z,Chang Y,Liu Y,Liu B,Zhen J,Li X,Lin J,Yu Q,Lv Z,Wang R

Tue Jun 14 00:00:00 UTC 2022

Blocking STAT3 signaling augments MEK/ERK inhibitor efficacy in esophageal squamous cell carcinoma.

Cell death & disease

Zheng ZY,Chu MY,Lin W,Zheng YQ,Xu XE,Chen Y,Liao LD,Wu ZY,Wang SH,Li EM,Xu LY

Wed May 25 00:00:00 UTC 2022

Recombinant ACE2 protein protects against acute lung injury induced by SARS-CoV-2 spike RBD protein.

Critical care (London, England)

Zhang L,Zhang Y,Qin X,Jiang X,Zhang J,Mao L,Jiang Z,Jiang Y,Liu G,Qiu J,Chen C,Qiu F,Zou Z

Thu Jun 09 00:00:00 UTC 2022

Recombinant ACE2 protein protects against acute lung injury induced by SARS-CoV-2 spike RBD protein.

Critical care (London, England)

Zhang L,Zhang Y,Qin X,Jiang X,Zhang J,Mao L,Jiang Z,Jiang Y,Liu G,Qiu J,Chen C,Qiu F,Zou Z

Thu Jun 09 00:00:00 UTC 2022

Human Cytomegalovirus UL24 and UL43 Cooperate to Modulate the Expression of Immunoregulatory UL16 Binding Protein 1.

Viral immunology

Sleman S,Hao H,Najmuldeen H,Jalal P,Saeed N,Othman D,Qian Z

Sat Oct 01 00:00:00 UTC 2022

Human Cytomegalovirus UL24 and UL43 Cooperate to Modulate the Expression of Immunoregulatory UL16 Binding Protein 1.

Viral immunology

Sleman S,Hao H,Najmuldeen H,Jalal P,Saeed N,Othman D,Qian Z

Sat Oct 01 00:00:00 UTC 2022

The deubiquitinases UBP12 and UBP13 integrate with the E3 ubiquitin ligase XBAT35.2 to modulate VPS23A stability in ABA signaling.

Science advances

Liu G,Liang J,Lou L,Tian M,Zhang X,Liu L,Zhao Q,Xia R,Wu Y,Xie Q,Yu F

Fri Apr 08 00:00:00 UTC 2022

The mitochondrial calcium uniporter engages UCP1 to form a thermoporter that promotes thermogenesis.

Cell metabolism

Xue K,Wu D,Wang Y,Zhao Y,Shen H,Yao J,Huang X,Li X,Zhou Z,Wang Z,Qiu Y

Tue Sep 06 00:00:00 UTC 2022

The mitochondrial calcium uniporter engages UCP1 to form a thermoporter that promotes thermogenesis.

Cell metabolism

Xue K,Wu D,Wang Y,Zhao Y,Shen H,Yao J,Huang X,Li X,Zhou Z,Wang Z,Qiu Y

Tue Sep 06 00:00:00 UTC 2022

BtpB inhibits innate inflammatory responses in goat alveolar macrophages through the TLR/NF-κB pathway and NLRP3 inflammasome during Brucella infection.

Microbial pathogenesis

Li J,Zhang G,Zhi F,Zhai Y,Zhou D,Chen H,Lin P,Tang K,Liu W,Jin Y,Wang A

Sun May 01 00:00:00 UTC 2022

Alternative splicing of the human rhomboid family-1 gene RHBDF1 inhibits epidermal growth factor receptor activation.

The Journal of biological chemistry

Ji R,Shi Q,Cao Y,Zhang J,Zhao C,Zhao H,Sayyed Y,Fu L,Li LY

Wed Jun 01 00:00:00 UTC 2022

Bcl-3 regulates the function of Th17 cells through raptor mediated glycolysis metabolism.

Frontiers in immunology

Liu H,Zeng L,Yang Y,Huang Z,Guo C,Huang L,Niu X,Zhang C,Wang H

Wed Sep 28 00:00:00 UTC 2022

Secreted EMC10 is upregulated in human obesity and its neutralizing antibody prevents diet-induced obesity in mice.

Nature communications

Wang X,Li Y,Qiang G,Wang K,Dai J,McCann M,Munoz MD,Gil V,Yu Y,Li S,Yang Z,Xu S,Cordoba-Chacon J,De Jesus DF,Sun B,Chen K,Wang Y,Liu X,Miao Q,Zhou L,Hu R,Ding Q,Kulkarni RN,Gao D,Blüher M,Liew CW

Mon Nov 28 00:00:00 UTC 2022

Secreted EMC10 is upregulated in human obesity and its neutralizing antibody prevents diet-induced obesity in mice.

Nature communications

Wang X,Li Y,Qiang G,Wang K,Dai J,McCann M,Munoz MD,Gil V,Yu Y,Li S,Yang Z,Xu S,Cordoba-Chacon J,De Jesus DF,Sun B,Chen K,Wang Y,Liu X,Miao Q,Zhou L,Hu R,Ding Q,Kulkarni RN,Gao D,Blüher M,Liew CW

Mon Nov 28 00:00:00 UTC 2022

MACC1 promotes pancreatic cancer metastasis by interacting with the EMT regulator SNAI1.

Cell death & disease

Zhang X,Luo Y,Cen Y,Qiu X,Li J,Jie M,Yang S,Qin S

Fri Nov 04 00:00:00 UTC 2022

Protein arginine methyltransferase 3 promotes glycolysis and hepatocellular carcinoma growth by enhancing arginine methylation of lactate dehydrogenase A.

Clinical and translational medicine

Lei Y,Han P,Chen Y,Wang H,Wang S,Wang M,Liu J,Yan W,Tian D,Liu M

Sat Jan 01 00:00:00 UTC 2022

MAPK signalling-induced phosphorylation and subcellular translocation of PDHE1α promotes tumour immune evasion.

Nature metabolism

Zhang Y,Zhao M,Gao H,Yu G,Zhao Y,Yao F,Yang W

Tue Mar 01 00:00:00 UTC 2022

MAPK signalling-induced phosphorylation and subcellular translocation of PDHE1α promotes tumour immune evasion.

Nature metabolism

Zhang Y,Zhao M,Gao H,Yu G,Zhao Y,Yao F,Yang W

Tue Mar 01 00:00:00 UTC 2022

The MFN1 and MFN2 mitofusins promote clustering between mitochondria and peroxisomes.

Communications biology

Huo Y,Sun W,Shi T,Gao S,Zhuang M

Fri May 06 00:00:00 UTC 2022

A novel role of TCAIM: suppressing renal carcinoma growth and enhancing its sensitivity to sunitinib.

The FEBS journal

Ye Z,Ren C,Wang Q,Wang Y

Thu Sep 01 00:00:00 UTC 2022

KLHL38 facilitates staurosporine-induced apoptosis in HL-1 cells via myocardin degradation.

IUBMB life

Luo Y,Tian L,Liang C,Xu Y

Sun May 01 00:00:00 UTC 2022

KLHL38 facilitates staurosporine-induced apoptosis in HL-1 cells via myocardin degradation.

IUBMB life

Luo Y,Tian L,Liang C,Xu Y

Sun May 01 00:00:00 UTC 2022

Mutations in GCK May Lead to MODY2 by Reducing Glycogen Synthesis.

Advanced biology

Li Z,Li K,Sun Y,Jiang X,Liu J,Li J,Fang L,Li G,Guan Q,Xu C

Tue Nov 01 00:00:00 UTC 2022

The dual role of p62 in ferroptosis of glioblastoma according to p53 status.

Cell & bioscience

Yuan F,Sun Q,Zhang S,Ye L,Xu Y,Deng G,Xu Z,Zhang S,Liu B,Chen Q

Fri Feb 25 00:00:00 UTC 2022

The dual role of p62 in ferroptosis of glioblastoma according to p53 status.

Cell & bioscience

Yuan F,Sun Q,Zhang S,Ye L,Xu Y,Deng G,Xu Z,Zhang S,Liu B,Chen Q

Fri Feb 25 00:00:00 UTC 2022

Ribonucleotide reductase holoenzyme inhibitor COH29 interacts with deubiquitinase ubiquitin-specific protease 2 and downregulates its substrate protein cyclin D1.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Zhu M,Wang H,Ding Y,Yang Y,Xu Z,Shi L,Zhang N

Sun May 01 00:00:00 UTC 2022

LPS/Bcl3/YAP1 signaling promotes Sox9⁺HNF4α⁺ hepatocyte-mediated liver regeneration after hepatectomy.

Cell death & disease

Shao C,Jing Y,Zhao S,Yang X,Hu Y,Meng Y,Huang Y,Ye F,Gao L,Liu W,Sheng D,Li R,Zhang X,Wei L

Mon Mar 28 00:00:00 UTC 2022

A redox cycle with complex II prioritizes sulfide quinone oxidoreductase-dependent H₂S oxidation.

The Journal of biological chemistry

Kumar R,Landry AP,Guha A,Vitvitsky V,Lee HJ,Seike K,Reddy P,Lyssiotis CA,Banerjee R

Sat Jan 01 00:00:00 UTC 2022

SUFU suppresses ferroptosis sensitivity in breast cancer cells via Hippo/YAP pathway.

iScience

Fang K,Du S,Shen D,Xiong Z,Jiang K,Liang D,Wang J,Xu H,Hu L,Zhai X,Jiang Y,Xia Z,Xie C,Jin D,Cheng W,Meng S,Wang Y

Fri Jul 15 00:00:00 UTC 2022

SUFU suppresses ferroptosis sensitivity in breast cancer cells via Hippo/YAP pathway.

iScience

Fang K,Du S,Shen D,Xiong Z,Jiang K,Liang D,Wang J,Xu H,Hu L,Zhai X,Jiang Y,Xia Z,Xie C,Jin D,Cheng W,Meng S,Wang Y

Fri Jul 15 00:00:00 UTC 2022

The Role of CD147 in Pathological Cardiac Hypertrophy Is Regulated by Glycosylation.

Oxidative medicine and cellular longevity

Zhong FY,Zhao YC,Zhao CX,Gu ZC,Lu XY,Jiang WL,Gao LC,Li WL,Qin ZH,Ge H,Pu J

Fri Mar 11 00:00:00 UTC 2022

Top3α is the replicative topoisomerase in mitochondrial DNA replication.

Nucleic acids research

Hangas A,Kekäläinen NJ,Potter A,Michell C,Aho KJ,Rutanen C,Spelbrink JN,Pohjoismäki JL,Goffart S

Fri Aug 26 00:00:00 UTC 2022

PRMT5 critically mediates TMAO-induced inflammatory response in vascular smooth muscle cells.

Cell death & disease

Liu H,Jia K,Ren Z,Sun J,Pan LL

Mon Apr 04 00:00:00 UTC 2022

Global crotonylome reveals hypoxia-mediated lamin A crotonylation regulated by HDAC6 in liver cancer.

Cell death & disease

Zhang D,Tang J,Xu Y,Huang X,Wang Y,Jin X,Wu G,Liu P

Wed Aug 17 00:00:00 UTC 2022

Global crotonylome reveals hypoxia-mediated lamin A crotonylation regulated by HDAC6 in liver cancer.

Cell death & disease

Zhang D,Tang J,Xu Y,Huang X,Wang Y,Jin X,Wu G,Liu P

Wed Aug 17 00:00:00 UTC 2022

HERC3 directly targets RPL23A for ubiquitination degradation and further regulates Colorectal Cancer proliferation and the cell cycle.

International journal of biological sciences

Zhang Z,Wu Q,Fang M,Liu Y,Jiang J,Feng Q,Hu R,Xu J

Thu Jun 02 00:00:00 UTC 2022

HERC3 directly targets RPL23A for ubiquitination degradation and further regulates Colorectal Cancer proliferation and the cell cycle.

International journal of biological sciences

Zhang Z,Wu Q,Fang M,Liu Y,Jiang J,Feng Q,Hu R,Xu J

Thu Jun 02 00:00:00 UTC 2022

Tyrosine phosphorylation tunes chemical and thermal sensitivity of TRPV2 ion channel.

eLife

Mo X,Pang P,Wang Y,Jiang D,Zhang M,Li Y,Wang P,Geng Q,Xie C,Du HN,Zhong B,Li D,Yao J

Fri Jun 10 00:00:00 UTC 2022

TRPC channels blockade abolishes endotoxemic cardiac dysfunction by hampering intracellular inflammation and Ca²⁺ leakage.

Nature communications

Tang N,Tian W,Ma GY,Xiao X,Zhou L,Li ZZ,Liu XX,Li CY,Wu KH,Liu W,Wang XY,Gao YY,Yang X,Qi J,Li D,Liu Y,Chen WS,Gao J,Li XQ,Cao W

Fri Dec 02 00:00:00 UTC 2022

Microarray screening reveals two non-conventional SUMO-binding modules linked to DNA repair by non-homologous end-joining.

Nucleic acids research

Cabello-Lobato MJ,Jenner M,Cisneros-Aguirre M,Brüninghoff K,Sandy Z,da Costa IC,Jowitt TA,Loch CM,Jackson SP,Wu Q,Mootz HD,Stark JM,Cliff MJ,Schmidt CK

Fri May 06 00:00:00 UTC 2022

NAP1L5 targeting combined with MYH9 Inhibit HCC progression through PI3K/AKT/mTOR signaling pathway.

Aging

Zhao R,Ge Y,Gong Y,Li B,Xiao B,Zuo S

Fri Nov 11 00:00:00 UTC 2022

Drebrin promotes lung adenocarcinoma cell migration through inducing integrin β1 endocytosis.

Biochemical and biophysical research communications

Yu Q,Tang F,Cao F,Tan X,Weng L,Sun L

Sat Nov 19 00:00:00 UTC 2022

Nedd4-2 Haploinsufficiency in Mice Impairs the Ubiquitination of Rer1 and Increases the Susceptibility to Endoplasmic Reticulum Stress and Seizures.

Frontiers in molecular neuroscience

Liu X,Zhang L,Zhang H,Liang X,Zhang B,Tu J,Zhao Y

Sat Jul 16 00:00:00 UTC 2022

Glycosylphosphatidylinositol-anchored micronemal antigen (GAMA) interacts with the band 3 receptor to promote erythrocyte invasion by malaria parasites.

The Journal of biological chemistry

Lu J,Chu R,Yin Y,Yu H,Xu Q,Yang B,Sun Y,Song J,Wang Q,Xu J,Lu F,Cheng Y

Fri Apr 01 00:00:00 UTC 2022

Inhibition of nuclear deacetylase Sirtuin-1 induces mitochondrial acetylation and calcium overload leading to cell death.

Redox biology

Sun Y,Yang YM,Hu YY,Ouyang L,Sun ZH,Yin XF,Li N,He QY,Wang Y

Fri Jul 01 00:00:00 UTC 2022

Inhibition of nuclear deacetylase Sirtuin-1 induces mitochondrial acetylation and calcium overload leading to cell death.

Redox biology

Sun Y,Yang YM,Hu YY,Ouyang L,Sun ZH,Yin XF,Li N,He QY,Wang Y

Fri Jul 01 00:00:00 UTC 2022

LncRNA-MEG3 attenuates hyperglycemia-induced damage by enhancing mitochondrial translocation of HSP90A in the primary hippocampal neurons.

Experimental cell research

Zhou W,Wang Z,Tao Y,Chen C,Zhang Q,Liu Z,Li L,Xia P,Ye Z

Sat Oct 15 00:00:00 UTC 2022

LncRNA-MEG3 attenuates hyperglycemia-induced damage by enhancing mitochondrial translocation of HSP90A in the primary hippocampal neurons.

Experimental cell research

Zhou W,Wang Z,Tao Y,Chen C,Zhang Q,Liu Z,Li L,Xia P,Ye Z

Sat Oct 15 00:00:00 UTC 2022

HSP27 Attenuates cGAS-Mediated IFN-β Signaling through Ubiquitination of cGAS and Promotes PRV Infection.

Viruses

Li X,Xie J,Li D,Li H,Niu Y,Wu B,Yang Y,Yan Z,Zhang X,Chen L,Feng R

Tue Aug 23 00:00:00 UTC 2022

EGFR tyrosine kinase activity and Rab GTPases coordinate EGFR trafficking to regulate macrophage activation in sepsis.

Cell death & disease

Zhang X,Chen C,Ling C,Luo S,Xiong Z,Liu X,Liao C,Xie P,Liu Y,Zhang L,Chen Z,Liu Z,Tang J

Mon Nov 07 00:00:00 UTC 2022

EGFR tyrosine kinase activity and Rab GTPases coordinate EGFR trafficking to regulate macrophage activation in sepsis.

Cell death & disease

Zhang X,Chen C,Ling C,Luo S,Xiong Z,Liu X,Liao C,Xie P,Liu Y,Zhang L,Chen Z,Liu Z,Tang J

Mon Nov 07 00:00:00 UTC 2022

EGFR tyrosine kinase activity and Rab GTPases coordinate EGFR trafficking to regulate macrophage activation in sepsis.

Cell death & disease

Zhang X,Chen C,Ling C,Luo S,Xiong Z,Liu X,Liao C,Xie P,Liu Y,Zhang L,Chen Z,Liu Z,Tang J

Mon Nov 07 00:00:00 UTC 2022

EGFR tyrosine kinase activity and Rab GTPases coordinate EGFR trafficking to regulate macrophage activation in sepsis.

Cell death & disease

Zhang X,Chen C,Ling C,Luo S,Xiong Z,Liu X,Liao C,Xie P,Liu Y,Zhang L,Chen Z,Liu Z,Tang J

Mon Nov 07 00:00:00 UTC 2022

PACT promotes the metastasis of basal-like breast cancer through Rac1 SUMOylation and activation.

Oncogene

Wei L,Wang W,Yao J,Cui Z,Xu Z,Ding H,Wu X,Wang D,Luo J,Ke ZJ

Thu Sep 01 00:00:00 UTC 2022

PACT promotes the metastasis of basal-like breast cancer through Rac1 SUMOylation and activation.

Oncogene

Wei L,Wang W,Yao J,Cui Z,Xu Z,Ding H,Wu X,Wang D,Luo J,Ke ZJ

Thu Sep 01 00:00:00 UTC 2022

Spatiotemporal modulation of SMAD4 by HBx is required for cellular proliferation in hepatitis B-related liver cancer.

Cellular oncology (Dordrecht)

Chaomin W,Wenhao N,Jialei H,Ting Z,Honglei F,Zhuang H,Yichao W,Changsen B,Yueguo L

Mon Aug 01 00:00:00 UTC 2022

L2Δ13, a splicing isoform of lysyl oxidase-like 2, causes adipose tissue loss via the gut microbiota and lipid metabolism.

iScience

Chen Y,He LX,Chen JL,Xu X,Wang JJ,Zhan XH,Jiao JW,Dong G,Li EM,Xu LY

Fri Sep 16 00:00:00 UTC 2022

The lncRNA BDNF-AS/WDR5/FBXW7 axis mediates ferroptosis in gastric cancer peritoneal metastasis by regulating VDAC3 ubiquitination.

International journal of biological sciences

Huang G,Xiang Z,Wu H,He Q,Dou R,Lin Z,Yang C,Huang S,Song J,Di Z,Wang S,Xiong B

Fri Apr 15 00:00:00 UTC 2022

Native proline-rich motifs exploit sequence context to target actin-remodeling Ena/VASP protein ENAH.

eLife

Hwang T,Parker SS,Hill SM,Grant RA,Ilunga MW,Sivaraman V,Mouneimne G,Keating AE

Tue Jan 25 00:00:00 UTC 2022

Novel RARS2 Variants: Updating the Diagnosis and Pathogenesis of Pontocerebellar Hypoplasia Type 6.

Pediatric neurology

Zhang Y,Yu Y,Zhao X,Xu Y,Chen L,Li N,Yao R,Wang J,Yu T

Wed Jun 01 00:00:00 UTC 2022

Identification of icaritin derivative IC2 as an SCD-1 inhibitor with anti-breast cancer properties through induction of cell apoptosis.

Cancer cell international

Yang C,Jin YY,Mei J,Hu D,Jiao X,Che HL,Tang CL,Zhang Y,Wu GS

Tue May 31 00:00:00 UTC 2022

Rab22a cooperates with Rab5 and NS4B in classical swine fever virus entry process.

Veterinary microbiology

Wang T,Liu Y,Sun Y,Zhang L,Guo K,Zhang Y

Tue Mar 01 00:00:00 UTC 2022

Rab22a cooperates with Rab5 and NS4B in classical swine fever virus entry process.

Veterinary microbiology

Wang T,Liu Y,Sun Y,Zhang L,Guo K,Zhang Y

Tue Mar 01 00:00:00 UTC 2022

CHMP2B regulates TDP-43 phosphorylation and cytotoxicity independent of autophagy via CK1.

The Journal of cell biology

Deng X,Sun X,Yue W,Duan Y,Hu R,Zhang K,Ni J,Cui J,Wang Q,Chen Y,Li A,Fang Y

Mon Jan 03 00:00:00 UTC 2022

The transcription factor KLF14 attenuates LPS-induced acute lung injury by ameliorating apoptosis of alveolar epithelial cells in mice.

Molecular immunology

Liu L,Yuan Y,Zhou Y,Yao L,Li J,Chen F

Thu Dec 01 00:00:00 UTC 2022

GpsB Coordinates Cell Division and Cell Surface Decoration by Wall Teichoic Acids in Staphylococcus aureus.

Microbiology spectrum

Hammond LR,Sacco MD,Khan SJ,Spanoudis C,Hough-Neidig A,Chen Y,Eswara PJ

Wed Jun 29 00:00:00 UTC 2022

Development of a novel PROTAC using the nucleic acid aptamer as a targeting ligand for tumor selective degradation of nucleolin.

Molecular therapy. Nucleic acids

Zhang L,Li L,Wang X,Liu H,Zhang Y,Xie T,Zhang H,Li X,Peng T,Sun X,Dai J,Liu J,Wu W,Ye M,Tan W

Tue Dec 13 00:00:00 UTC 2022

NBR1 mediates autophagic degradation of IRF3 to negatively regulate type I interferon production.

Biochemical and biophysical research communications

Cai Y,Zhu Y,Zheng J,Zhang Y,Chen W

Sat Oct 01 00:00:00 UTC 2022

NBR1 mediates autophagic degradation of IRF3 to negatively regulate type I interferon production.

Biochemical and biophysical research communications

Cai Y,Zhu Y,Zheng J,Zhang Y,Chen W

Sat Oct 01 00:00:00 UTC 2022

hnRNPH1 recruits PTBP2 and SRSF3 to modulate alternative splicing in germ cells.

Nature communications

Feng S,Li J,Wen H,Liu K,Gui Y,Wen Y,Wang X,Yuan S

Thu Jun 23 00:00:00 UTC 2022

hnRNPH1 recruits PTBP2 and SRSF3 to modulate alternative splicing in germ cells.

Nature communications

Feng S,Li J,Wen H,Liu K,Gui Y,Wen Y,Wang X,Yuan S

Thu Jun 23 00:00:00 UTC 2022

Human cytomegalovirus UL24 and UL43 products participate in SAMHD1 subcellular localization.

Virusdisease

Sleman S,Najmuldeen H,Hao H,Jalal P,Saeed N,Othman D,Qian Z

Thu Dec 01 00:00:00 UTC 2022

Human cytomegalovirus UL24 and UL43 products participate in SAMHD1 subcellular localization.

Virusdisease

Sleman S,Najmuldeen H,Hao H,Jalal P,Saeed N,Othman D,Qian Z

Thu Dec 01 00:00:00 UTC 2022

KAP1 phosphorylation promotes the survival of neural stem cells after ischemia/reperfusion by maintaining the stability of PCNA.

Stem cell research & therapy

Wang W,Yan T,Guo X,Cai H,Liang C,Huang L,Wang Y,Ma P,Qi S

Thu Jul 07 00:00:00 UTC 2022

KAP1 phosphorylation promotes the survival of neural stem cells after ischemia/reperfusion by maintaining the stability of PCNA.

Stem cell research & therapy

Wang W,Yan T,Guo X,Cai H,Liang C,Huang L,Wang Y,Ma P,Qi S

Thu Jul 07 00:00:00 UTC 2022

A novel NPHS2 mutation (c.865A > G) identified in a Chinese family with steroid-resistant nephrotic syndrome alters subcellular localization of nephrin.

Genes & genomics

Wu N,Zhu Y,Jiang W,Song Y,Yin L,Lu Y,Tao D,Liu Y,Ma Y

Sun May 01 00:00:00 UTC 2022

A novel NPHS2 mutation (c.865A > G) identified in a Chinese family with steroid-resistant nephrotic syndrome alters subcellular localization of nephrin.

Genes & genomics

Wu N,Zhu Y,Jiang W,Song Y,Yin L,Lu Y,Tao D,Liu Y,Ma Y

Sun May 01 00:00:00 UTC 2022

A novel NPHS2 mutation (c.865A > G) identified in a Chinese family with steroid-resistant nephrotic syndrome alters subcellular localization of nephrin.

Genes & genomics

Wu N,Zhu Y,Jiang W,Song Y,Yin L,Lu Y,Tao D,Liu Y,Ma Y

Sun May 01 00:00:00 UTC 2022

GPX4 degradation via chaperone-mediated autophagy contributes to antimony-triggered neuronal ferroptosis.

Ecotoxicology and environmental safety

Yu S,Li Z,Zhang Q,Wang R,Zhao Z,Ding W,Wang F,Sun C,Tang J,Wang X,Zhang H,Huang R,Wu Q,Jiang J,Zhao X

Fri Apr 01 00:00:00 UTC 2022

AMPK-ChREBP axis mediates de novo milk fatty acid synthesis promoted by glucose in the mammary gland of lactating goats.

Animal nutrition (Zhongguo xu mu shou yi xue hui)

Shi H,Jiang N,Wei L,Cai J,Zhang W,Jiang Q,Loor JJ,Liu J

Thu Sep 01 00:00:00 UTC 2022

ADAR1p110 promotes Enterovirus D68 replication through its deaminase domain and inhibition of PKR pathway.

Virology journal

Zhang K,Wang S,Chen T,Tu Z,Huang X,Zang G,Wu C,Fan X,Liu J,Tian Y,Cheng Y,Lu N,Zhang G

Thu Dec 22 00:00:00 UTC 2022

ADAR1p110 promotes Enterovirus D68 replication through its deaminase domain and inhibition of PKR pathway.

Virology journal

Zhang K,Wang S,Chen T,Tu Z,Huang X,Zang G,Wu C,Fan X,Liu J,Tian Y,Cheng Y,Lu N,Zhang G

Thu Dec 22 00:00:00 UTC 2022

Avian Hepatitis E Virus ORF2 Protein Interacts with Rap1b to Induce Cytoskeleton Rearrangement That Facilitates Virus Internalization.

Microbiology spectrum

Zhang B,Fan M,Fan J,Luo Y,Wang J,Wang Y,Liu B,Sun Y,Zhao Q,Hiscox JA,Nan Y,Zhou EM

Wed Feb 23 00:00:00 UTC 2022

Avian Hepatitis E Virus ORF2 Protein Interacts with Rap1b to Induce Cytoskeleton Rearrangement That Facilitates Virus Internalization.

Microbiology spectrum

Zhang B,Fan M,Fan J,Luo Y,Wang J,Wang Y,Liu B,Sun Y,Zhao Q,Hiscox JA,Nan Y,Zhou EM

Wed Feb 23 00:00:00 UTC 2022

S-acylation regulates the membrane association and activity of Calpain-5.

Biochimica et biophysica acta. Molecular cell research

Gal J,Bondada V,Mashburn CB,Rodgers DW,Croall DE,Geddes JW

Thu Sep 01 00:00:00 UTC 2022

Mitochondrial microproteins link metabolic cues to respiratory chain biogenesis.

Cell reports

Liang C,Zhang S,Robinson D,Ploeg MV,Wilson R,Nah J,Taylor D,Beh S,Lim R,Sun L,Muoio DM,Stroud DA,Ho L

Tue Aug 16 00:00:00 UTC 2022

m⁶A Modification of Long Non-Coding RNA HNF1A-AS1 Facilitates Cell Cycle Progression in Colorectal Cancer via IGF2BP2-Mediated CCND1 mRNA Stabilization.

Cells

Bian Y,Wang Y,Xu S,Gao Z,Li C,Fan Z,Ding J,Wang K

Tue Sep 27 00:00:00 UTC 2022

A novel NF2 splicing mutant causes neurofibromatosis type 2 via liquid-liquid phase separation with large tumor suppressor and Hippo pathway.

iScience

Jia Z,Yang S,Li M,Lei Z,Ding X,Fan M,Wang D,Xie D,Zhou H,Qiu Y,Zhuang Q,Li D,Yang W,Qi X,Cang X,Zhao JW,Wang W,Lin A,Yan Q

Fri Nov 18 00:00:00 UTC 2022

m⁶A demethylase FTO regulate CTNNB1 to promote adipogenesis of chicken preadipocyte.

Journal of animal science and biotechnology

Li K,Huang W,Wang Z,Nie Q

Fri Dec 02 00:00:00 UTC 2022

The interaction of O-GlcNAc-modified NLRX1 and IKK-α modulates IL-1β expression in M1 macrophages.

In vitro cellular & developmental biology. Animal

Chen L,Li Y,Zeng S,Duan S,Huang Z,Liang Y

Sun May 01 00:00:00 UTC 2022

SPTLC1 variants associated with ALS produce distinct sphingolipid signatures through impaired interaction with ORMDL proteins.

The Journal of clinical investigation

Lone MA,Aaltonen MJ,Zidell A,Pedro HF,Morales Saute JA,Mathew S,Mohassel P,Bönnemann CG,Shoubridge EA,Hornemann T

Thu Sep 15 00:00:00 UTC 2022

GNAQ T96S mutation abrogates the ability of wild-type GNAQ to induce apoptosis by phosphorylating annexin A2 in natural killer/T cell lymphoma.

Cancer science

Zhao W,Zhang M,Wang G,Liu E,Jiang G,Zhang Y,Zhang D,Jian X,Zhao H,Zhang C,Li W

Fri Jul 01 00:00:00 UTC 2022

Lactylation of PKM2 Suppresses Inflammatory Metabolic Adaptation in Pro-inflammatory Macrophages.

International journal of biological sciences

Wang J,Yang P,Yu T,Gao M,Liu D,Zhang J,Lu C,Chen X,Zhang X,Liu Y

Tue Nov 29 00:00:00 UTC 2022

MICAL1 inhibits colorectal cancer cell migration and proliferation by regulating the EGR1/β-catenin signaling pathway.

Biochemical pharmacology

Gu H,Li Y,Cui X,Cao H,Hou Z,Ti Y,Liu D,Gao J,Wang Y,Wen P

Sat Jan 01 00:00:00 UTC 2022

Identification of a novel GATA binding protein 5 variant (c.830C>T/p.P277L) damaging the nuclear translocation and causing tetralogy of Fallot.

QJM : monthly journal of the Association of Physicians

Jin JY,Wu LP,Dong Y,Pi HC,Wu HF,Xiang R

Wed Apr 20 00:00:00 UTC 2022

S-palmitoylation of PCSK9 induces sorafenib resistance in liver cancer by activating the PI3K/AKT pathway.

Cell reports

Sun Y,Zhang H,Meng J,Guo F,Ren D,Wu H,Jin X

Tue Aug 16 00:00:00 UTC 2022

Novel Heterozygous Mutations in ZP2 Cause Abnormal Zona Pellucida and Female Infertility.

Reproductive sciences (Thousand Oaks, Calif.)

Hou M,Zhu L,Jiang J,Liu Z,Li Z,Jia W,Hu J,Zhou X,Zhang D,Luo Y,Peng X,Xi Q,Jin L,Zhang X

Sat Oct 01 00:00:00 UTC 2022

Retinoic Acid Receptor Gamma (RARγ) Promotes Cartilage Destruction through Positive Feedback Activation of NF-κB Pathway in Human Osteoarthritis.

Mediators of inflammation

Yu YW,Li SY,Zhang LJ,Wang QL,Liu ZG,Chen QZ,Song HY,Shen DY,Yan J

Mon Nov 21 00:00:00 UTC 2022

Retinoic Acid Receptor Gamma (RARγ) Promotes Cartilage Destruction through Positive Feedback Activation of NF-κB Pathway in Human Osteoarthritis.

Mediators of inflammation

Yu YW,Li SY,Zhang LJ,Wang QL,Liu ZG,Chen QZ,Song HY,Shen DY,Yan J

Mon Nov 21 00:00:00 UTC 2022

STARD3NL inhibits the osteogenic differentiation by inactivating the Wnt/β-catenin pathway via binding to Annexin A2 in osteoporosis.

Journal of cellular and molecular medicine

Xu Y,Bao X,Chen X,Wu P,Chen S,Zhang B,Ma J,Xu G,Ma D

Tue Mar 01 00:00:00 UTC 2022

STARD3NL inhibits the osteogenic differentiation by inactivating the Wnt/β-catenin pathway via binding to Annexin A2 in osteoporosis.

Journal of cellular and molecular medicine

Xu Y,Bao X,Chen X,Wu P,Chen S,Zhang B,Ma J,Xu G,Ma D

Tue Mar 01 00:00:00 UTC 2022

Up-regulation of cell division cycle 20 expression alters the morphology of neuronal dendritic spines in the nucleus accumbens by promoting FMRP ubiquitination.

Journal of neurochemistry

Wang X,Li F,Zhu J,Feng D,Shi Y,Qu L,Li Y,Guo K,Zhang Y,Wang Q,Wang N,Wang X,Ge S

Fri Jul 01 00:00:00 UTC 2022

miR21 modulates the Hippo signaling pathway via interference with PP2A Bβ to inhibit trophoblast invasion and cause preeclampsia.

Molecular therapy. Nucleic acids

Hu M,Zheng Y,Liao J,Wen L,Cheng J,Huang J,Huang B,Lin L,Long Y,Wu Y,Ye X,Fu Y,Qi H,Baker PN,Tong C

Tue Dec 13 00:00:00 UTC 2022

Intertwined Wdr47-NTD dimer recognizes a basic-helical motif in Camsap proteins for proper central-pair microtubule formation.

Cell reports

Ren J,Li D,Liu J,Liu H,Yan X,Zhu X,Feng W

Tue Nov 08 00:00:00 UTC 2022

Genome-Wide Analysis of the Indispensable Role of Non-structural Proteins in the Replication of SARS-CoV-2.

Frontiers in microbiology

Jin Y,Ouyang M,Yu T,Zhuang J,Wang W,Liu X,Duan F,Guo D,Peng X,Pan JA

Sat Jul 16 00:00:00 UTC 2022

Lysine crotonylation regulates leucine-deprivation-induced autophagy by a 14-3-3ε-PPM1B axis.

Cell reports

Zheng Z,Yan G,Li X,Fei Y,Sun L,Yu H,Niu Y,Gao W,Zhong Q,Yan X

Tue Dec 20 00:00:00 UTC 2022

Upregulation of miR-520c-3p via hepatitis B virus drives hepatocellular migration and invasion by the PTEN/AKT/NF-κB axis.

Molecular therapy. Nucleic acids

Liu Y,Wang J,Chen J,Wu S,Zeng X,Xiong Q,Guo Y,Sun J,Song F,Xu J,Yuan S,Li C,He Y,Wang M,Chen L,Shi YB,Guo M,Guo D,Sun G

Tue Sep 13 00:00:00 UTC 2022

Upregulation of miR-520c-3p via hepatitis B virus drives hepatocellular migration and invasion by the PTEN/AKT/NF-κB axis.

Molecular therapy. Nucleic acids

Liu Y,Wang J,Chen J,Wu S,Zeng X,Xiong Q,Guo Y,Sun J,Song F,Xu J,Yuan S,Li C,He Y,Wang M,Chen L,Shi YB,Guo M,Guo D,Sun G

Tue Sep 13 00:00:00 UTC 2022

METTL3 acetylation impedes cancer metastasis via fine-tuning its nuclear and cytosolic functions.

Nature communications

Li Y,He X,Lu X,Gong Z,Li Q,Zhang L,Yang R,Wu C,Huang J,Ding J,He Y,Liu W,Chen C,Cao B,Zhou D,Shi Y,Chen J,Wang C,Zhang S,Zhang J,Ye J,You H

Wed Oct 26 00:00:00 UTC 2022

I226R Protein of African Swine Fever Virus Is a Suppressor of Innate Antiviral Responses.

Viruses

Hong J,Chi X,Yuan X,Wen F,Rai KR,Wu L,Song Z,Wang S,Guo G,Chen JL

Fri Mar 11 00:00:00 UTC 2022

Characterization and subcellular localization of Alongshan virus proteins.

Frontiers in microbiology

Zhao Y,Wu P,Liu L,Ma B,Pan M,Huang Y,Du N,Yu H,Sui L,Wang ZD,Hou Z,Liu Q

Sat Oct 15 00:00:00 UTC 2022

Characterization and subcellular localization of Alongshan virus proteins.

Frontiers in microbiology

Zhao Y,Wu P,Liu L,Ma B,Pan M,Huang Y,Du N,Yu H,Sui L,Wang ZD,Hou Z,Liu Q

Sat Oct 15 00:00:00 UTC 2022

Characterization and subcellular localization of Alongshan virus proteins.

Frontiers in microbiology

Zhao Y,Wu P,Liu L,Ma B,Pan M,Huang Y,Du N,Yu H,Sui L,Wang ZD,Hou Z,Liu Q

Sat Oct 15 00:00:00 UTC 2022

Fbxo45 facilitates pancreatic carcinoma progression by targeting USP49 for ubiquitination and degradation.

Cell death & disease

Wu L,Yu K,Chen K,Zhu X,Yang Z,Wang Q,Gao J,Wang Y,Cao T,Xu H,Pan X,Wang L,Xia J,Li Y,Wang ZP,Ma J

Sat Mar 12 00:00:00 UTC 2022

Fbxo45 facilitates pancreatic carcinoma progression by targeting USP49 for ubiquitination and degradation.

Cell death & disease

Wu L,Yu K,Chen K,Zhu X,Yang Z,Wang Q,Gao J,Wang Y,Cao T,Xu H,Pan X,Wang L,Xia J,Li Y,Wang ZP,Ma J

Sat Mar 12 00:00:00 UTC 2022

Quantitative proteomics of HFD-induced fatty liver uncovers novel transcription factors of lipid metabolism.

International journal of biological sciences

Zhi S,Congcong Z,Zhiling G,Yihan Q,Yijing X,Guanjie L,Fang W,Xuehua S,Hongjie L,Xiaoni K,Yueqiu G

Thu Jun 02 00:00:00 UTC 2022

Highly expressed SERCA2 triggers tumor cell autophagy and is a druggable vulnerability in triple-negative breast cancer.

Acta pharmaceutica Sinica. B

Fan M,Gao J,Zhou L,Xue W,Wang Y,Chen J,Li W,Yu Y,Liu B,Shen Y,Xu Q

Thu Dec 01 00:00:00 UTC 2022

Highly expressed SERCA2 triggers tumor cell autophagy and is a druggable vulnerability in triple-negative breast cancer.

Acta pharmaceutica Sinica. B

Fan M,Gao J,Zhou L,Xue W,Wang Y,Chen J,Li W,Yu Y,Liu B,Shen Y,Xu Q

Thu Dec 01 00:00:00 UTC 2022

R158Q and G212S, novel pathogenic compound heterozygous variants in SLC12A3 of Gitelman syndrome.

Frontiers of medicine

Li Z,Wu H,Wei S,Liu M,Shi Y,Li M,Wang N,Fang L,Xiang B,Gao L,Xu C,Zhao J

Thu Dec 01 00:00:00 UTC 2022

R158Q and G212S, novel pathogenic compound heterozygous variants in SLC12A3 of Gitelman syndrome.

Frontiers of medicine

Li Z,Wu H,Wei S,Liu M,Shi Y,Li M,Wang N,Fang L,Xiang B,Gao L,Xu C,Zhao J

Thu Dec 01 00:00:00 UTC 2022

SIRT2 promotes the viability, invasion and metastasis of osteosarcoma cells by inhibiting the degradation of Snail.

Cell death & disease

Tian Y,Liu R,Hou X,Gao Z,Liu X,Zhang W

Mon Nov 07 00:00:00 UTC 2022

Identification of host cell proteins that interact with the M protein of Pigeon paramyxovirus type 1.

Protein expression and purification

Tao X,Zheng B,Liu X,Zhou T,Li B

Mon Aug 01 00:00:00 UTC 2022

Identification of host cell proteins that interact with the M protein of Pigeon paramyxovirus type 1.

Protein expression and purification

Tao X,Zheng B,Liu X,Zhou T,Li B

Mon Aug 01 00:00:00 UTC 2022

The N-terminal region (VP4) of the foot-and-mouth disease capsid precursor (P1-2A) is not required during its synthesis to allow subsequent processing by the 3C protease.

Virology

Kristensen T,Normann P,Belsham GJ

Sun May 01 00:00:00 UTC 2022

A yes-associated protein 1- Notch1 receptor positive feedback loop promotes breast cancer lung metastasis by attenuating the bone morphogenetic protein 4-SMAD family member 1/5 signaling.

Carcinogenesis

Zhao L,Lei J,Gu S,Zhang Y,Jing X,Wang L,Zhang L,Ning Q,Luo M,Qi Y,Zhao X,Shao S

Sat Dec 31 00:00:00 UTC 2022

Ketogenic diet ameliorates lipid dysregulation in type 2 diabetic mice by downregulating hepatic pescadillo 1.

Molecular medicine (Cambridge, Mass.)

Zhou J,Lu Y,Jia Y,Lu J,Jiang Z,Chen K

Mon Jan 03 00:00:00 UTC 2022

Function of PHEX mutations p.Glu145* and p.Trp749Arg in families with X-linked hypophosphatemic rickets by the negative regulation mechanism on FGF23 promoter transcription.

Cell death & disease

Gan YM,Zhang YP,Ruan DD,Huang JB,Zhu YB,Lin XF,Xiao XP,Cheng Q,Geng ZB,Liao LS,Tang FQ,Luo JW

Thu Jun 02 00:00:00 UTC 2022

Hyperphosphorylated tau mediates neuronal death by inducing necroptosis and inflammation in Alzheimer's disease.

Journal of neuroinflammation

Dong Y,Yu H,Li X,Bian K,Zheng Y,Dai M,Feng X,Sun Y,He Y,Yu B,Zhang H,Wu J,Yu X,Wu H,Kong W

Mon Aug 15 00:00:00 UTC 2022

Hyperphosphorylated tau mediates neuronal death by inducing necroptosis and inflammation in Alzheimer's disease.

Journal of neuroinflammation

Dong Y,Yu H,Li X,Bian K,Zheng Y,Dai M,Feng X,Sun Y,He Y,Yu B,Zhang H,Wu J,Yu X,Wu H,Kong W

Mon Aug 15 00:00:00 UTC 2022

lncRNA lnc-POP1-1 upregulated by VN1R5 promotes cisplatin resistance in head and neck squamous cell carcinoma through interaction with MCM5.

Molecular therapy : the journal of the American Society of Gene Therapy

Jiang Y,Guo H,Tong T,Xie F,Qin X,Wang X,Chen W,Zhang J

Wed Jan 05 00:00:00 UTC 2022

lncRNA lnc-POP1-1 upregulated by VN1R5 promotes cisplatin resistance in head and neck squamous cell carcinoma through interaction with MCM5.

Molecular therapy : the journal of the American Society of Gene Therapy

Jiang Y,Guo H,Tong T,Xie F,Qin X,Wang X,Chen W,Zhang J

Wed Jan 05 00:00:00 UTC 2022

Ubiquitylation of cyclin C by HACE1 regulates cisplatin-associated sensitivity in gastric cancer.

Clinical and translational medicine

Jiang HY,Chen YL,Xu XX,Li CY,Chen Y,Li DP,Zeng XQ,Gao H

Tue Mar 01 00:00:00 UTC 2022

Up-regulation of NMRK2 mediated by TFE3 fusions is the key for energy metabolism adaption of Xp11.2 translocation renal cell carcinoma.

Cancer letters

Chen Y,Yang L,Lu Y,Liu N,Ma W,Fan H,Hu Q,Han X,Gan W,Li D

Sun Jul 10 00:00:00 UTC 2022

Up-regulation of NMRK2 mediated by TFE3 fusions is the key for energy metabolism adaption of Xp11.2 translocation renal cell carcinoma.

Cancer letters

Chen Y,Yang L,Lu Y,Liu N,Ma W,Fan H,Hu Q,Han X,Gan W,Li D

Sun Jul 10 00:00:00 UTC 2022

Cholesterylation of Smoothened is a calcium-accelerated autoreaction involving an intramolecular ester intermediate.

Cell research

Hu A,Zhang JZ,Wang J,Li CC,Yuan M,Deng G,Lin ZC,Qiu ZP,Liu HY,Wang XW,Wei PC,He X,Zhao X,Qiu WW,Song BL

Tue Mar 01 00:00:00 UTC 2022

GNIP1 functions both as a scaffold protein and an E3 ubiquitin ligase to regulate autophagy in lung cancer.

Cell communication and signaling : CCS

Zhou F,Liu Y,Ai W,Wang Y,Gan M,Jiang Q,Han T,Wang JB

Tue Aug 30 00:00:00 UTC 2022

WDFY1, a WD40 repeat protein, is not essential for spermatogenesis and male fertility in mice.

Biochemical and biophysical research communications

Lv C,Xiong M,Guo S,Gui Y,Liu X,Wang X,Wu Y,Feng S,Zhang J,Zhang Y,Liu Y,Qin W,Yuan S

Sat Mar 12 00:00:00 UTC 2022

WDFY1, a WD40 repeat protein, is not essential for spermatogenesis and male fertility in mice.

Biochemical and biophysical research communications

Lv C,Xiong M,Guo S,Gui Y,Liu X,Wang X,Wu Y,Feng S,Zhang J,Zhang Y,Liu Y,Qin W,Yuan S

Sat Mar 12 00:00:00 UTC 2022

CIP4 targeted to recruit GTP-Cdc42 involving in invadopodia formation via NF-κB signaling pathway promotes invasion and metastasis of CRC.

Molecular therapy oncolytics

Hu Z,Zhu J,Ma Y,Long T,Gao L,Zhong Y,Wang X,Li Z

Thu Mar 17 00:00:00 UTC 2022

TRIM21 regulates pyroptotic cell death by promoting Gasdermin D oligomerization.

Cell death and differentiation

Gao W,Li Y,Liu X,Wang S,Mei P,Chen Z,Liu K,Li S,Xu XW,Gan J,Wu J,Ji C,Ding C,Liu X,Lai Y,He HH,Lieberman J,Wu H,Chen X,Li J

Tue Feb 01 00:00:00 UTC 2022

Cap-binding complex assists RNA polymerase II transcription in plant salt stress response.

Plant, cell & environment

Zhang H,Li X,Song R,Zhan Z,Zhao F,Li Z,Jiang D

Thu Sep 01 00:00:00 UTC 2022

HBx inhibits DNA sensing signaling pathway via ubiquitination and autophagy of cGAS.

Virology journal

Chen H,Jiang L,Chen S,Hu Q,Huang Y,Wu Y,Chen W

Mon Mar 28 00:00:00 UTC 2022

CRL2^ZER1/ZYG11B recognizes small N-terminal residues for degradation.

Nature communications

Li Y,Zhao Y,Yan X,Ye C,Weirich S,Zhang B,Wang X,Song L,Jiang C,Jeltsch A,Dong C,Mi W

Sat Dec 10 00:00:00 UTC 2022

CRL2^ZER1/ZYG11B recognizes small N-terminal residues for degradation.

Nature communications

Li Y,Zhao Y,Yan X,Ye C,Weirich S,Zhang B,Wang X,Song L,Jiang C,Jeltsch A,Dong C,Mi W

Sat Dec 10 00:00:00 UTC 2022

ABHD16A Negatively Regulates the Palmitoylation and Antiviral Function of IFITM Proteins.

mBio

Shi X,Li X,Xu Z,Shen L,Ding Y,Chen S,Mao L,Liu W,Xu J

Tue Dec 20 00:00:00 UTC 2022

TRIM59 guards ER proteostasis and prevents Bortezomib-mediated colorectal cancer (CRC) cells' killing.

Investigational new drugs

Feng X,Yang G,Zhang L,Tao S,Shim JS,Chen L,Wu Q

Thu Dec 01 00:00:00 UTC 2022

Mouse Ocilrp2/Clec2i negatively regulates LPS-mediated IL-6 production by blocking Dap12-Syk interaction in macrophage.

Frontiers in immunology

Cao M,Ma L,Yan C,Wang H,Ran M,Chen Y,Wang X,Liang X,Chai L,Li X

Fri Oct 28 00:00:00 UTC 2022

Lactylation-driven METTL3-mediated RNA m⁶A modification promotes immunosuppression of tumor-infiltrating myeloid cells.

Molecular cell

Xiong J,He J,Zhu J,Pan J,Liao W,Ye H,Wang H,Song Y,Du Y,Cui B,Xue M,Zheng W,Kong X,Jiang K,Ding K,Lai L,Wang Q

Thu May 05 00:00:00 UTC 2022

Lactylation-driven METTL3-mediated RNA m⁶A modification promotes immunosuppression of tumor-infiltrating myeloid cells.

Molecular cell

Xiong J,He J,Zhu J,Pan J,Liao W,Ye H,Wang H,Song Y,Du Y,Cui B,Xue M,Zheng W,Kong X,Jiang K,Ding K,Lai L,Wang Q

Thu May 05 00:00:00 UTC 2022

Lactylation-driven METTL3-mediated RNA m⁶A modification promotes immunosuppression of tumor-infiltrating myeloid cells.

Molecular cell

Xiong J,He J,Zhu J,Pan J,Liao W,Ye H,Wang H,Song Y,Du Y,Cui B,Xue M,Zheng W,Kong X,Jiang K,Ding K,Lai L,Wang Q

Thu May 05 00:00:00 UTC 2022

SDR7-6, a short-chain alcohol dehydrogenase/reductase family protein, regulates light-dependent cell death and defence responses in rice.

Molecular plant pathology

Zheng Y,Zhu Y,Mao X,Jiang M,Wei Y,Lian L,Xu H,Chen L,Xie H,Lu G,Zhang J

Sat Jan 01 00:00:00 UTC 2022

Novel CIC variants identified in individuals with neurodevelopmental phenotypes.

Human mutation

Sharma S,Hourigan B,Patel Z,Rosenfeld JA,Chan KM,Wangler MF,Yi JS,Lehman A,Horvath G,Cloos PA,Tan Q

Fri Jul 01 00:00:00 UTC 2022

Ubiquitin-specific protease 47 regulates intestinal inflammation through deubiquitination of TRAF6 in epithelial cells.

Science China. Life sciences

Lei H,Yang L,Xu H,Wang Z,Li X,Liu M,Wu Y

Mon Aug 01 00:00:00 UTC 2022

IGF2BP3 promotes progression of gallbladder carcinoma by stabilizing KLK5 mRNA in N⁶-methyladenosine-dependent binding.

Frontiers in oncology

Zhang J,Yang K,Bu J,Yan J,Hu X,Liu K,Gao S,Tang S,Gao L,Chen W

Wed Nov 02 00:00:00 UTC 2022

The central scaffold protein CEP350 coordinates centriole length, stability, and maturation.

The Journal of cell biology

Karasu OR,Neuner A,Atorino ES,Pereira G,Schiebel E

Mon Dec 05 00:00:00 UTC 2022

A novel protein encoded by ZCRB1-induced circHEATR5B suppresses aerobic glycolysis of GBM through phosphorylation of JMJD5.

Journal of experimental & clinical cancer research : CR

Song J,Zheng J,Liu X,Dong W,Yang C,Wang D,Ruan X,Zhao Y,Liu L,Wang P,Zhang M,Liu Y

Tue May 10 00:00:00 UTC 2022

RNA-assisted sequestration of RNA-binding proteins by cytoplasmic inclusions of the C-terminal 35-kDa fragment of TDP-43.

Journal of cell science

Jiang LL,Guan WL,Wang JY,Zhang SX,Hu HY

Tue Mar 15 00:00:00 UTC 2022

RNA-assisted sequestration of RNA-binding proteins by cytoplasmic inclusions of the C-terminal 35-kDa fragment of TDP-43.

Journal of cell science

Jiang LL,Guan WL,Wang JY,Zhang SX,Hu HY

Tue Mar 15 00:00:00 UTC 2022

RNA-assisted sequestration of RNA-binding proteins by cytoplasmic inclusions of the C-terminal 35-kDa fragment of TDP-43.

Journal of cell science

Jiang LL,Guan WL,Wang JY,Zhang SX,Hu HY

Tue Mar 15 00:00:00 UTC 2022

SETD8 stabilized by USP17 epigenetically activates SREBP1 pathway to drive lipogenesis and oncogenesis of ccRCC.

Cancer letters

Li X,Liu Z,Xia C,Yan K,Fang Z,Fan Y

Mon Feb 28 00:00:00 UTC 2022

Regulation of Podocyte Injury by CircHIPK3/FUS Complex in Diabetic Kidney Disease.

International journal of biological sciences

Liu F,Huang J,Zhang C,Xie Y,Cao Y,Tao L,Tang H,Lin J,Hammes HP,Huang K,Yi F,Su H,Zhang C

Fri Oct 21 00:00:00 UTC 2022

Regulation of Podocyte Injury by CircHIPK3/FUS Complex in Diabetic Kidney Disease.

International journal of biological sciences

Liu F,Huang J,Zhang C,Xie Y,Cao Y,Tao L,Tang H,Lin J,Hammes HP,Huang K,Yi F,Su H,Zhang C

Fri Oct 21 00:00:00 UTC 2022

Cellular protein HSC70 promotes fowl adenovirus serotype 4 replication in LMH cells via interacting with viral 100K protein.

Poultry science

Gao S,Chen H,Zhang X,Zhao J,Wang Z

Fri Jul 01 00:00:00 UTC 2022

HIV-1 gp120 Protein Activates Cyclin-Dependent Kinase 1, a Possible Link to Central Nervous System Cell Death.

Viruses

Saro A,Gao Z,Kambey PA,Li M,Huang J

Thu Dec 15 00:00:00 UTC 2022

Connexin32 ameliorates epithelial-to-mesenchymal-transition in diabetic renal tubular via inhibiting NOX4.

Pharmacological research

Sun X,Xiao H,Li S,Chen R,Lin Z,Yang Y,Chen Z,Deng L,Huang H

Tue Feb 01 00:00:00 UTC 2022

Connexin32 ameliorates epithelial-to-mesenchymal-transition in diabetic renal tubular via inhibiting NOX4.

Pharmacological research

Sun X,Xiao H,Li S,Chen R,Lin Z,Yang Y,Chen Z,Deng L,Huang H

Tue Feb 01 00:00:00 UTC 2022

Serine palmitoyltransferase assembles at ER-mitochondria contact sites.

Life science alliance

Aaltonen MJ,Alecu I,König T,Bennett SA,Shoubridge EA

Tue Feb 01 00:00:00 UTC 2022

MFSD4A inhibits the malignant progression of nasopharyngeal carcinoma by targeting EPHA2.

Cell death & disease

Yang H,Qin G,Luo Z,Kong X,Gan C,Zhang R,Jiang W

Mon Apr 11 00:00:00 UTC 2022

ARHGEF3 regulates the stability of ACLY to promote the proliferation of lung cancer.

Cell death & disease

Zhou F,Ai W,Zhang Y,Hu Q,Gan M,Wang JB,Han T

Fri Oct 14 00:00:00 UTC 2022

ARHGEF3 regulates the stability of ACLY to promote the proliferation of lung cancer.

Cell death & disease

Zhou F,Ai W,Zhang Y,Hu Q,Gan M,Wang JB,Han T

Fri Oct 14 00:00:00 UTC 2022

FAM64A promotes HNSCC tumorigenesis by mediating transcriptional autoregulation of FOXM1.

International journal of oral science

Zhao X,Chen H,Qiu Y,Cui L

Tue May 10 00:00:00 UTC 2022

Rab31 promotes the invasion and metastasis of cervical cancer cells by inhibiting MAPK6 degradation.

International journal of biological sciences

Huang Y,Liu R,Han X,Hou X,Tian Y,Zhang W

Mon Mar 28 00:00:00 UTC 2022

TRIM3 facilitates estrogen signaling and modulates breast cancer cell progression.

Cell communication and signaling : CCS

Zhuang T,Wang B,Tan X,Wu L,Li X,Li Z,Cai Y,Fan R,Yang X,Zhang C,Xia Y,Niu Z,Liu B,Cao Q,Ding Y,Zhou Z,Huang Q,Yang H

Thu Apr 07 00:00:00 UTC 2022

RNF31 represses cell progression and immune evasion via YAP/PD-L1 suppression in triple negative breast Cancer.

Journal of experimental & clinical cancer research : CR

Yang H,Xue M,Su P,Zhou Y,Li X,Li Z,Xia Y,Zhang C,Fu M,Zheng X,Luo G,Wei T,Wang X,Ding Y,Zhu J,Zhuang T

Thu Dec 29 00:00:00 UTC 2022

RNF31 represses cell progression and immune evasion via YAP/PD-L1 suppression in triple negative breast Cancer.

Journal of experimental & clinical cancer research : CR

Yang H,Xue M,Su P,Zhou Y,Li X,Li Z,Xia Y,Zhang C,Fu M,Zheng X,Luo G,Wei T,Wang X,Ding Y,Zhu J,Zhuang T

Thu Dec 29 00:00:00 UTC 2022

The transcription factor KLF14 regulates macrophage glycolysis and immune function by inhibiting HK2 in sepsis.

Cellular & molecular immunology

Yuan Y,Fan G,Liu Y,Liu L,Zhang T,Liu P,Tu Q,Zhang X,Luo S,Yao L,Chen F,Li J

Fri Apr 01 00:00:00 UTC 2022

African Swine Fever Virus pI215L Inhibits Type I Interferon Signaling by Targeting Interferon Regulatory Factor 9 for Autophagic Degradation.

Journal of virology

Li L,Fu J,Li J,Guo S,Chen Q,Zhang Y,Liu Z,Tan C,Chen H,Wang X

Wed Sep 14 00:00:00 UTC 2022

African Swine Fever Virus pI215L Inhibits Type I Interferon Signaling by Targeting Interferon Regulatory Factor 9 for Autophagic Degradation.

Journal of virology

Li L,Fu J,Li J,Guo S,Chen Q,Zhang Y,Liu Z,Tan C,Chen H,Wang X

Wed Sep 14 00:00:00 UTC 2022

Expression of GALNT8 and O-glycosylation of BMP receptor 1A suppress breast cancer cell proliferation by upregulating ERα levels.

Biochimica et biophysica acta. General subjects

Huang T,Wu Q,Huang H,Zhang C,Wang L,Wang L,Liu Y,Li W,Zhang J,Liu Y

Sat Jan 01 00:00:00 UTC 2022

ISG15 enhances glioma cell stemness by promoting Oct4 protein stability.

Environmental toxicology

Dai Y,Yu T,Yu C,Lu T,Zhou L,Cheng C,Ni H

Thu Sep 01 00:00:00 UTC 2022

ISG15 enhances glioma cell stemness by promoting Oct4 protein stability.

Environmental toxicology

Dai Y,Yu T,Yu C,Lu T,Zhou L,Cheng C,Ni H

Thu Sep 01 00:00:00 UTC 2022

Ubiquitination of NLRP3 by gp78/Insig-1 restrains NLRP3 inflammasome activation.

Cell death and differentiation

Xu T,Yu W,Fang H,Wang Z,Chi Z,Guo X,Jiang D,Zhang K,Chen S,Li M,Guo Y,Zhang J,Yang D,Yu Q,Wang D,Zhang X

Mon Aug 01 00:00:00 UTC 2022

A novel mechanism for A-to-I RNA-edited AZIN1 in promoting tumor angiogenesis in colorectal cancer.

Cell death & disease

Wei Y,Zhang H,Feng Q,Wang S,Shao Y,Wu J,Jin G,Lin W,Peng X,Xu X

Sat Apr 02 00:00:00 UTC 2022

Phosphorylation of α-Catenin^S641 Suppresses the NF-κB Pathway in Fibroblasts to Activate Skin Wound Repair.

The Journal of investigative dermatology

Shen Y,Zhu Z,Cong W,Jiang M,Wang J,Chen X,Wang N,Yu Y,Dong Y,Liu Z,Sun J,Gong W,Zhang S,Kim K,Jin L

Wed Jun 01 00:00:00 UTC 2022

The deubiquitinating enzyme USP20 regulates the stability of the MCL1 protein.

Biochemical and biophysical research communications

Feng J,Liu P,Li X,Zhang D,Lin H,Hou Z,Guo C,Niu Y,Dai B,Wang O,Qi M,Wang H,Zhou H

Sat Feb 19 00:00:00 UTC 2022

The deubiquitinating enzyme USP20 regulates the stability of the MCL1 protein.

Biochemical and biophysical research communications

Feng J,Liu P,Li X,Zhang D,Lin H,Hou Z,Guo C,Niu Y,Dai B,Wang O,Qi M,Wang H,Zhou H

Sat Feb 19 00:00:00 UTC 2022

Hypoxia-mediated YTHDF2 overexpression promotes lung squamous cell carcinoma progression by activation of the mTOR/AKT axis.

Cancer cell international

Xu P,Hu K,Zhang P,Sun ZG,Zhang N

Fri Jan 07 00:00:00 UTC 2022

The transcriptional coactivator Eya1 exerts transcriptional repressive activity by interacting with REST corepressors and REST-binding sequences to maintain nephron progenitor identity.

Nucleic acids research

Li J,Cheng C,Xu J,Zhang T,Tokat B,Dolios G,Ramakrishnan A,Shen L,Wang R,Xu PX

Fri Oct 14 00:00:00 UTC 2022

Structures of NPAS4-ARNT and NPAS4-ARNT2 heterodimers reveal new dimerization modalities in the bHLH-PAS transcription factor family.

Proceedings of the National Academy of Sciences of the United States of America

Sun X,Jing L,Li F,Zhang M,Diao X,Zhuang J,Rastinejad F,Wu D

Wed Nov 16 00:00:00 UTC 2022

MCTS1 promotes laryngeal squamous cell carcinoma cell growth via enhancing LARP7 stability.

Clinical and experimental pharmacology & physiology

Yang M,Ma B,Liu X

Wed Jun 01 00:00:00 UTC 2022

SorCS3 promotes the internalization of p75^NTR to inhibit GBM progression.

Cell death & disease

Zhang Y,Li Y,Fan Y,Zhang X,Tang Z,Qi J,Zhao B,Li F,Chen X,Liang H,Xu H,Li D

Thu Apr 07 00:00:00 UTC 2022

SorCS3 promotes the internalization of p75^NTR to inhibit GBM progression.

Cell death & disease

Zhang Y,Li Y,Fan Y,Zhang X,Tang Z,Qi J,Zhao B,Li F,Chen X,Liang H,Xu H,Li D

Thu Apr 07 00:00:00 UTC 2022

Intracellular CYTL1, a novel tumor suppressor, stabilizes NDUFV1 to inhibit metabolic reprogramming in breast cancer.

Signal transduction and targeted therapy

Xue W,Li X,Li W,Wang Y,Jiang C,Zhou L,Gao J,Yu Y,Shen Y,Xu Q

Fri Feb 04 00:00:00 UTC 2022

Intracellular CYTL1, a novel tumor suppressor, stabilizes NDUFV1 to inhibit metabolic reprogramming in breast cancer.

Signal transduction and targeted therapy

Xue W,Li X,Li W,Wang Y,Jiang C,Zhou L,Gao J,Yu Y,Shen Y,Xu Q

Fri Feb 04 00:00:00 UTC 2022

Regulation of PTEN and ovarian cancer progression by an E3 ubiquitin ligase RBCK1.

Human cell

Wang G,Zhuang Z,Shen S,Yang F,Jiang Z,Liu Z,Wang T,Hua L

Sun May 01 00:00:00 UTC 2022

Regulation of PTEN and ovarian cancer progression by an E3 ubiquitin ligase RBCK1.

Human cell

Wang G,Zhuang Z,Shen S,Yang F,Jiang Z,Liu Z,Wang T,Hua L

Sun May 01 00:00:00 UTC 2022

Cytosolic peptides encoding Ca_V1 C-termini downregulate the calcium channel activity-neuritogenesis coupling.

Communications biology

Yang Y,Yu Z,Geng J,Liu M,Liu N,Li P,Hong W,Yue S,Jiang H,Ge H,Qian F,Xiong W,Wang P,Song S,Li X,Fan Y,Liu X

Thu May 19 00:00:00 UTC 2022

UHRF1 Induces Metastasis in Thyroid Cancer.

Journal of oncology

Kuang BH,Lin GH,Liu Q,Wang BC

Wed Aug 24 00:00:00 UTC 2022

UHRF1 Induces Metastasis in Thyroid Cancer.

Journal of oncology

Kuang BH,Lin GH,Liu Q,Wang BC

Wed Aug 24 00:00:00 UTC 2022

UHRF1 Induces Metastasis in Thyroid Cancer.

Journal of oncology

Kuang BH,Lin GH,Liu Q,Wang BC

Wed Aug 24 00:00:00 UTC 2022

USP19 (ubiquitin specific peptidase 19) promotes TBK1 (TANK-binding kinase 1) degradation via chaperone-mediated autophagy.

Autophagy

Zhao X,Di Q,Yu J,Quan J,Xiao Y,Zhu H,Li H,Ling J,Chen W

Fri Apr 01 00:00:00 UTC 2022

Licochalcone B specifically inhibits the NLRP3 inflammasome by disrupting NEK7-NLRP3 interaction.

EMBO reports

Li Q,Feng H,Wang H,Wang Y,Mou W,Xu G,Zhang P,Li R,Shi W,Wang Z,Fang Z,Ren L,Wang Y,Lin L,Hou X,Dai W,Li Z,Wei Z,Liu T,Wang J,Guo Y,Li P,Zhao X,Zhan X,Xiao X,Bai Z

Thu Feb 03 00:00:00 UTC 2022

TRIM26-mediated degradation of nucleocapsid protein limits porcine reproductive and respiratory syndrome virus-2 infection.

Virus research

Zhao P,Jing H,Dong W,Duan E,Ke W,Tao R,Li Y,Cao S,Wang H,Zhang Y,Sun Y,Wang J

Sat Apr 02 00:00:00 UTC 2022

TRIM26-mediated degradation of nucleocapsid protein limits porcine reproductive and respiratory syndrome virus-2 infection.

Virus research

Zhao P,Jing H,Dong W,Duan E,Ke W,Tao R,Li Y,Cao S,Wang H,Zhang Y,Sun Y,Wang J

Sat Apr 02 00:00:00 UTC 2022

Acetylation of Checkpoint suppressor 1 enhances its stability and promotes the progression of triple-negative breast cancer.

Cell death discovery

Xu Z,Liu S,Feng C,Xu F,Kong D,Mi J,Yang C,Zhang G,Wei P,Orgil BO,Bergquist J,Tian G

Thu Dec 01 00:00:00 UTC 2022

Acetylation of Checkpoint suppressor 1 enhances its stability and promotes the progression of triple-negative breast cancer.

Cell death discovery

Xu Z,Liu S,Feng C,Xu F,Kong D,Mi J,Yang C,Zhang G,Wei P,Orgil BO,Bergquist J,Tian G

Thu Dec 01 00:00:00 UTC 2022

The histone deacetylase 1/GSK3/SHAGGY-like kinase 2/BRASSINAZOLE-RESISTANT 1 module controls lateral root formation in rice.

Plant physiology

Hou J,Zheng X,Ren R,Shi Q,Xiao H,Chen Z,Yue M,Wu Y,Hou H,Li L

Wed Jun 01 00:00:00 UTC 2022

Targeting IL-6 by engineered Lactococcus lactis via surface-displayed affibody.

Microbial cell factories

Zahirović A,Berlec A

Sat Jul 16 00:00:00 UTC 2022

Targeting IL-6 by engineered Lactococcus lactis via surface-displayed affibody.

Microbial cell factories

Zahirović A,Berlec A

Sat Jul 16 00:00:00 UTC 2022

PBK drives PARP inhibitor resistance through the TRIM37/NFκB axis in ovarian cancer.

Experimental & molecular medicine

Ma H,Qi G,Han F,Peng J,Yuan C,Kong B

Fri Jul 01 00:00:00 UTC 2022

Chaperone-mediated Autophagy Regulates Cell Growth by Targeting SMAD3 in Glioma.

Neuroscience bulletin

Liu H,Yong Y,Li X,Ye P,Tao K,Peng G,Mo M,Guo W,Chen X,Luo Y,Lin Y,Qiu J,Zhang Z,Ding L,Zhou M,Yang X,Lu L,Yang Q,Xu P

Wed Jun 01 00:00:00 UTC 2022

Chaperone-mediated Autophagy Regulates Cell Growth by Targeting SMAD3 in Glioma.

Neuroscience bulletin

Liu H,Yong Y,Li X,Ye P,Tao K,Peng G,Mo M,Guo W,Chen X,Luo Y,Lin Y,Qiu J,Zhang Z,Ding L,Zhou M,Yang X,Lu L,Yang Q,Xu P

Wed Jun 01 00:00:00 UTC 2022

Chaperone-mediated autophagy degrades Keap1 and promotes Nrf2-mediated antioxidative response.

Aging cell

Zhu L,He S,Huang L,Ren D,Nie T,Tao K,Xia L,Lu F,Mao Z,Yang Q

Wed Jun 01 00:00:00 UTC 2022

LncRNA MT1DP promotes cadmium-induced DNA replication stress by inhibiting chromatin recruitment of SMARCAL1.

The Science of the total environment

Feng W,Qi Z,Dong Z,Liu W,Xu M,Gao M,Liu S

Thu Feb 10 00:00:00 UTC 2022

The mechanism of the imbalance between proliferation and ferroptosis in pulmonary artery smooth muscle cells based on the activation of SLC7A11.

European journal of pharmacology

Hu P,Xu Y,Jiang Y,Huang J,Liu Y,Wang D,Tao T,Sun Z,Liu Y

Fri Aug 05 00:00:00 UTC 2022

NRBF2 regulates the chemoresistance of small cell lung cancer by interacting with the P62 protein in the autophagy process.

iScience

Shen W,Luo P,Sun Y,Zhang W,Zhou N,Zhan H,Zhang Q,Shen J,Lin A,Cheng Q,Wang Q,Zhang J,Wang HH,Wei T

Fri Jun 17 00:00:00 UTC 2022

TaFDL2-1A confers drought stress tolerance by promoting ABA biosynthesis, ABA responses, and ROS scavenging in transgenic wheat.

The Plant journal : for cell and molecular biology

Wang B,Li L,Liu M,Peng D,Wei A,Hou B,Lei Y,Li X

Tue Nov 01 00:00:00 UTC 2022

Modular assembly of the principal microtubule nucleator γ-TuRC.

Nature communications

Würtz M,Zupa E,Atorino ES,Neuner A,Böhler A,Rahadian AS,Vermeulen BJA,Tonon G,Eustermann S,Schiebel E,Pfeffer S

Tue Jan 25 00:00:00 UTC 2022

Modular assembly of the principal microtubule nucleator γ-TuRC.

Nature communications

Würtz M,Zupa E,Atorino ES,Neuner A,Böhler A,Rahadian AS,Vermeulen BJA,Tonon G,Eustermann S,Schiebel E,Pfeffer S

Tue Jan 25 00:00:00 UTC 2022

Functional Attenuation of UCP1 as the Potential Mechanism for a Thickened Blubber Layer in Cetaceans.

Molecular biology and evolution

Zhou M,Wu T,Chen Y,Xu S,Yang G

Thu Nov 03 00:00:00 UTC 2022

C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7.

Proceedings of the National Academy of Sciences of the United States of America

Ru Y,Yan X,Zhang B,Song L,Feng Q,Ye C,Zhou Z,Yang Z,Li Y,Zhang Z,Li Q,Mi W,Dong C

Tue Jul 26 00:00:00 UTC 2022

ZEB2/TWIST1/PRMT5/NuRD Multicomplex Contributes to the Epigenetic Regulation of EMT and Metastasis in Colorectal Carcinoma.

Cancers

Zheng Y,Dai M,Dong Y,Yu H,Liu T,Feng X,Yu B,Zhang H,Wu J,Kong W,Yu X,Wu H

Thu Jul 14 00:00:00 UTC 2022

ENSMUST00000147869 regulates proliferation and fibrosis of mesangial cells in diabetic nephropathy by interacting with Hspa9.

IUBMB life

Wang M,Chen X,Zhang H,Li L,Xu Y,Lu W,Lu Y

Sun May 01 00:00:00 UTC 2022

Iron-regulated assembly of the cytosolic iron-sulfur cluster biogenesis machinery.

The Journal of biological chemistry

Fan X,Barshop WD,Vashisht AA,Pandey V,Leal S,Rayatpisheh S,Jami-Alahmadi Y,Sha J,Wohlschlegel JA

Fri Jul 01 00:00:00 UTC 2022

Ubiquitination of G3BP1 mediates stress granule disassembly in a context-specific manner.

Science (New York, N.Y.)

Gwon Y,Maxwell BA,Kolaitis RM,Zhang P,Kim HJ,Taylor JP

Fri Jun 25 00:00:00 UTC 2021

An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress.

Molecular cell

Nüchel J,Tauber M,Nolte JL,Mörgelin M,Türk C,Eckes B,Demetriades C,Plomann M

Thu Aug 19 00:00:00 UTC 2021

Poly(ADP-ribosyl)ation enhances HuR oligomerization and contributes to pro-inflammatory gene mRNA stabilization.

Cellular and molecular life sciences : CMLS

Ke Y,Lv X,Fu X,Zhang J,Bohio AA,Zeng X,Hao W,Wang R,Boldogh I,Ba X

Mon Feb 01 00:00:00 UTC 2021

Galectin-8 Is Upregulated in Keratinocytes by IL-17A and Promotes Proliferation by Regulating Mitosis in Psoriasis.

The Journal of investigative dermatology

Lo YH,Li CS,Chen HL,Chiang CY,Huang CC,Tu TJ,Lo TH,Choy DF,Arron JR,Chen HY,Liu FT

Mon Mar 01 00:00:00 UTC 2021

The stabilization of yes-associated protein by TGFβ-activated kinase 1 regulates the self-renewal and oncogenesis of gastric cancer stem cells.

Journal of cellular and molecular medicine

Wang G,Sun Q,Zhu H,Bi Y,Zhu H,Xu A

Thu Jul 01 00:00:00 UTC 2021

Neutralizing Antibodies and Cellular Immune Responses Against SARS-CoV-2 Sustained One and a Half Years After Natural Infection.

Frontiers in microbiology

Yan LN,Liu PP,Li XG,Zhou SJ,Li H,Wang ZY,Shen F,Lu BC,Long Y,Xiao X,Wang ZD,Li D,Han HJ,Yu H,Zhou SH,Lv WL,Yu XJ

Tue Mar 22 00:00:00 UTC 2022

DDX21, a Host Restriction Factor of FMDV IRES-Dependent Translation and Replication.

Viruses

Abdullah SW,Wu J,Zhang Y,Bai M,Guan J,Liu X,Sun S,Guo H

Fri Sep 03 00:00:00 UTC 2021

De novo variants in H3-3A and H3-3B are associated with neurodevelopmental delay, dysmorphic features, and structural brain abnormalities.

NPJ genomic medicine

Okur V,Chen Z,Vossaert L,Peacock S,Rosenfeld J,Zhao L,Du H,Calamaro E,Gerard A,Zhao S,Kelsay J,Lahr A,Mighton C,Porter HM,Siemon A,Silver J,Svihovec S,Fong CT,Grant CL,Lerner-Ellis J,Manickam K,Madan-Khetarpal S,McCandless SE,Morel CF,Schaefer GB,Berry-Kravis EM,Gates R,Gomez-Ospina N,Qiu G,Zhang TJ,Wu Z,Meng L,Liu P,Scott DA,Lupski JR,Eng CM,Wu N,Yuan B

Tue Dec 07 00:00:00 UTC 2021

Heat shock protein 70, glutamate dehydrogenase, and angiotensin-converting enzyme of Bombyx mori mediate the cell attachment of Cypovirus 1.

The Journal of general virology

Yang J,Wang J,Peng X,Lei C,Sun X,Hu J

Wed Dec 01 00:00:00 UTC 2021

PRDX2 promotes the proliferation of colorectal cancer cells by increasing the ubiquitinated degradation of p53.

Cell death & disease

Wang W,Wei J,Zhang H,Zheng X,Zhou H,Luo Y,Yang J,Deng Q,Huang S,Fu Z

Fri Jun 11 00:00:00 UTC 2021

Overexpression of ARHGAP30 suppresses growth of cervical cancer cells by downregulating ribosome biogenesis.

Cancer science

Wu A,Lin L,Li X,Xu Q,Xu W,Zhu X,Teng Y,Yang XM,Ai Z

Mon Nov 01 00:00:00 UTC 2021

Lectin-Mediated Binding of Engineered Lactococcus lactis to Cancer Cells.

Microorganisms

Plavec TV,Zahirović A,Zadravec P,Sabotič J,Berlec A

Fri Jan 22 00:00:00 UTC 2021

Lectin-Mediated Binding of Engineered Lactococcus lactis to Cancer Cells.

Microorganisms

Plavec TV,Zahirović A,Zadravec P,Sabotič J,Berlec A

Fri Jan 22 00:00:00 UTC 2021

Genome-Wide Methylation Mapping Using Nanopore Sequencing Technology Identifies Novel Tumor Suppressor Genes in Hepatocellular Carcinoma.

International journal of molecular sciences

Davenport CF,Scheithauer T,Dunst A,Bahr FS,Dorda M,Wiehlmann L,Tran DDH

Sun Apr 11 00:00:00 UTC 2021

CSN6 promotes melanoma proliferation and metastasis by controlling the UBR5-mediated ubiquitination and degradation of CDK9.

Cell death & disease

Zhang Y,Hou J,Shi S,Du J,Liu Y,Huang P,Li Q,Liu L,Hu H,Ji Y,Guo L,Shi Y,Liu Y,Cui H

Fri Jan 22 00:00:00 UTC 2021

ZNF213 negatively controls triple negative breast cancer progression via Hippo/YAP signaling.

Cancer science

Liu Y,Su P,Zhao W,Li X,Yang X,Fan J,Yang H,Yan C,Mao L,Ding Y,Zhu J,Niu Z,Zhuang T

Thu Jul 01 00:00:00 UTC 2021

Mutant TP53 interacts with BCAR1 to contribute to cancer cell invasion.

British journal of cancer

Guo AK,Itahana Y,Seshachalam VP,Chow HY,Ghosh S,Itahana K

Fri Jan 01 00:00:00 UTC 2021

FOXO1 inhibits prostate cancer cell proliferation via suppressing E2F1 activated NPRL2 expression.

Cell biology international

Tang Y,Jiang L,Zhao X,Hu D,Zhao G,Luo S,Du X,Tang W

Wed Dec 01 00:00:00 UTC 2021

A γ-adducin cleavage fragment induces neurite deficits and synaptic dysfunction in Alzheimer's disease.

Progress in neurobiology

Xiong M,Zou L,Meng L,Zhang X,Tian Y,Zhang G,Yang J,Chen G,Xiong J,Ye K,Zhang Z

Sun Aug 01 00:00:00 UTC 2021

Hypothermic oxygenated perfusion inhibits HECTD3-mediated TRAF3 polyubiquitination to alleviate DCD liver ischemia-reperfusion injury.

Cell death & disease

Zhou W,Zhong Z,Lin D,Liu Z,Zhang Q,Xia H,Peng S,Liu A,Lu Z,Wang Y,Ye S,Ye Q

Wed Feb 24 00:00:00 UTC 2021

LncRNA-FKBP1C regulates muscle fiber type switching by affecting the stability of MYH1B.

Cell death discovery

Yu JA,Wang Z,Yang X,Ma M,Li Z,Nie Q

Fri Apr 09 00:00:00 UTC 2021

Coding and non-coding roles of MOCCI (C15ORF48) coordinate to regulate host inflammation and immunity.

Nature communications

Lee CQE,Kerouanton B,Chothani S,Zhang S,Chen Y,Mantri CK,Hock DH,Lim R,Nadkarni R,Huynh VT,Lim D,Chew WL,Zhong FL,Stroud DA,Schafer S,Tergaonkar V,St John AL,Rackham OJL,Ho L

Fri Apr 09 00:00:00 UTC 2021

Spodoptera frugiperda mRNA export factor interacts with and mediates the nuclear import of Autographa californica multiple nucleopolyhedrovirus ORF34 (Ac34).

Virus research

Tang Z,Luo W,Huang Z,Yuan M,Wu W,Yang K

Fri Jul 02 00:00:00 UTC 2021

TDP43 Exacerbates Atherosclerosis Progression by Promoting Inflammation and Lipid Uptake of Macrophages.

Frontiers in cell and developmental biology

Huangfu N,Wang Y,Xu Z,Zheng W,Tao C,Li Z,Hu Y,Chen X

Mon Apr 25 00:00:00 UTC 2022

SOX13/TRIM11/YAP axis promotes the proliferation, migration and chemoresistance of anaplastic thyroid cancer.

International journal of biological sciences

Tang J,Tian Z,Liao X,Wu G

Fri Jan 14 00:00:00 UTC 2022

Oncogenic AURKA-enhanced N⁶-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells.

Cell research

Peng F,Xu J,Cui B,Liang Q,Zeng S,He B,Zou H,Li M,Zhao H,Meng Y,Chen J,Liu B,Lv S,Chu P,An F,Wang Z,Huang J,Zhan Y,Liao Y,Lu J,Xu L,Zhang J,Sun Z,Li Z,Wang F,Lam EW,Liu Q

Mon Mar 01 00:00:00 UTC 2021

CircNR3C2 promotes HRD1-mediated tumor-suppressive effect via sponging miR-513a-3p in triple-negative breast cancer.

Molecular cancer

Fan Y,Wang J,Jin W,Sun Y,Xu Y,Wang Y,Liang X,Su D

Tue Feb 02 00:00:00 UTC 2021

The N-terminus of Sfi1 and yeast centrin Cdc31 provide the assembly site for a new spindle pole body.

The Journal of cell biology

Rüthnick D,Vitale J,Neuner A,Schiebel E

Mon Mar 01 00:00:00 UTC 2021

Oscillating lncRNA Platr4 regulates NLRP3 inflammasome to ameliorate nonalcoholic steatohepatitis in mice.

Theranostics

Lin Y,Wang S,Gao L,Zhou Z,Yang Z,Lin J,Ren S,Xing H,Wu B

Thu Aug 05 00:00:00 UTC 2021

NRF1 association with AUTS2-Polycomb mediates specific gene activation in the brain.

Molecular cell

Liu S,Aldinger KA,Cheng CV,Kiyama T,Dave M,McNamara HK,Zhao W,Stafford JM,Descostes N,Lee P,Caraffi SG,Ivanovski I,Errichiello E,Zweier C,Zuffardi O,Schneider M,Papavasiliou AS,Perry MS,Humberson J,Cho MT,Weber A,Swale A,Badea TC,Mao CA,Garavelli L,Dobyns WB,Reinberg D

Thu Nov 18 00:00:00 UTC 2021

Enterotoxigenic Escherichia coli infection promotes enteric defensin expression via FOXO6-METTL3-m⁶A-GPR161 signalling axis.

RNA biology

Zong X,Wang H,Xiao X,Zhang Y,Hu Y,Wang F,Wang Y,Lu Z

Thu Apr 01 00:00:00 UTC 2021

UBQLN4 is an ATM substrate that stabilizes the anti-apoptotic proteins BCL2A1 and BCL2L10 in mesothelioma.

Molecular oncology

Liu F,Pan R,Ding H,Gu L,Yang Y,Li C,Xu Y,Hu R,Chen H,Zhang X,Nie Y

Wed Dec 01 00:00:00 UTC 2021

The role of S-nitrosylation of PFKM in regulation of glycolysis in ovarian cancer cells.

Cell death & disease

Gao W,Huang M,Chen X,Chen J,Zou Z,Li L,Ji K,Nie Z,Yang B,Wei Z,Xu P,Jia J,Zhang Q,Shen H,Wang Q,Li K,Zhu L,Wang M,Ye S,Zeng S,Lin Y,Rong Z,Xu Y,Zhu P,Zhang H,Hao B,Liu Q

Thu Apr 15 00:00:00 UTC 2021

Screening and Functional Analysis of TEK Mutations in Chinese Children With Primary Congenital Glaucoma.

Frontiers in genetics

Qiao Y,Chen Y,Tan C,Sun X,Chen X,Chen J

Tue Dec 28 00:00:00 UTC 2021

A Novel Loss-of-Function MKRN3 Variant in a Chinese Patient With Familial Precocious Puberty: A Case Report and Functional Study.

Frontiers in genetics

Yin X,Wang J,Han T,Tingting Z,Li Y,Dong Z,Wang W,Li C,Lu W

Tue Aug 24 00:00:00 UTC 2021

Flotillin-1 Interacts With and Sustains the Surface Levels of TRPV2 Channel.

Frontiers in cell and developmental biology

Hu J,Gao Y,Huang Q,Wang Y,Mo X,Wang P,Zhang Y,Xie C,Li D,Yao J

Sat Feb 27 00:00:00 UTC 2021

Pantoprazole ameliorates liver fibrosis and suppresses hepatic stellate cell activation in bile duct ligation rats by promoting YAP degradation.

Acta pharmacologica Sinica

Lu ZN,Niu WX,Zhang N,Ge MX,Bao YY,Ren Y,Guo XL,He HW

Mon Nov 01 00:00:00 UTC 2021

Clock Gene Nr1d1 Alleviates Retinal Inflammation Through Repression of Hmga2 in Microglia.

Journal of inflammation research

Wang Z,Huang Y,Chu F,Ji S,Liao K,Cui Z,Chen J,Tang S

Thu Apr 28 00:00:00 UTC 2022

Essential role of zyxin in platelet biogenesis and glycoprotein Ib-IX surface expression.

Cell death & disease

Yan R,Ge X,Pang N,Ye H,Yuan L,Cheng B,Zhou K,Yang M,Sun Y,Zhang S,Ding Z,Luo J,Ruan C,Dai K

Sat Oct 16 00:00:00 UTC 2021

SALL1 regulates commitment of odontoblast lineages by interacting with RUNX2 to remodel open chromatin regions.

Stem cells (Dayton, Ohio)

Lin Y,Xiao Y,Lin C,Zhang Q,Zhang S,Pei F,Liu H,Chen Z

Mon Feb 01 00:00:00 UTC 2021

The missing linker between SUN5 and PMFBP1 in sperm head-tail coupling apparatus.

Nature communications

Zhang Y,Liu C,Wu B,Li L,Li W,Yuan L

Fri Aug 13 00:00:00 UTC 2021

The missing linker between SUN5 and PMFBP1 in sperm head-tail coupling apparatus.

Nature communications

Zhang Y,Liu C,Wu B,Li L,Li W,Yuan L

Fri Aug 13 00:00:00 UTC 2021

Clinical and molecular characterization of thirty Chinese patients with congenital lipoid adrenal hyperplasia.

The Journal of steroid biochemistry and molecular biology

Zhang T,Ma X,Wang J,Jia C,Wang W,Dong Z,Ye L,Sun S,Hu R,Ning G,Li C,Lu W

Mon Feb 01 00:00:00 UTC 2021

TSP50 promotes hepatocyte proliferation and tumour formation by activating glucose-6-phosphate dehydrogenase (G6PD).

Cell proliferation

Zhang X,Gao F,Ai H,Wang S,Song Z,Zheng L,Wang G,Sun Y,Bao Y

Thu Apr 01 00:00:00 UTC 2021

CBL aggravates Ang II-induced cardiac hypertrophy via the VHL/HIF-1α pathway.

Experimental cell research

Yang Y,Zou P,He L,Shao J,Tang Y,Li J

Sun Aug 15 00:00:00 UTC 2021

Cleavage of E-cadherin by porcine respiratory bacterial pathogens facilitates airway epithelial barrier disruption and bacterial paracellular transmigration.

Virulence

Cao Q,Wei W,Wang H,Wang Z,Lv Y,Dai M,Tan C,Chen H,Wang X

Wed Dec 01 00:00:00 UTC 2021

Transcriptional silencing of fetal hemoglobin expression by NonO.

Nucleic acids research

Li X,Chen M,Liu B,Lu P,Lv X,Zhao X,Cui S,Xu P,Nakamura Y,Kurita R,Chen B,Huang DCS,Liu DP,Liu M,Zhao Q

Mon Sep 27 00:00:00 UTC 2021

MFN2 interacts with nuage-associated proteins and is essential for male germ cell development by controlling mRNA fate during spermatogenesis.

Development (Cambridge, England)

Wang X,Wen Y,Zhang J,Swanson G,Guo S,Cao C,Krawetz SA,Zhang Z,Yuan S

Thu Apr 01 00:00:00 UTC 2021

PFKP facilitates ATG4B phosphorylation during amino acid deprivation-induced autophagy.

Cellular signalling

Li X,Sun L,Yan G,Yan X

Tue Jun 01 00:00:00 UTC 2021

HO-1 nuclear accumulation and interaction with NPM1 protect against stress-induced endothelial senescence independent of its enzymatic activity.

Cell death & disease

Luo W,Li J,Li Z,Lin T,Zhang L,Yang W,Mai Y,Liu R,Chen M,Dai C,Yang H,Lu J,Li H,Guan G,Huang M,Liu P,Li Z

Mon Jul 26 00:00:00 UTC 2021

USP19 promotes hypoxia-induced mitochondrial division via FUNDC1 at ER-mitochondria contact sites.

The Journal of cell biology

Chai P,Cheng Y,Hou C,Yin L,Zhang D,Hu Y,Chen Q,Zheng P,Teng J,Chen J

Mon Jul 05 00:00:00 UTC 2021

miRNA-223 Suppresses Mouse Gallstone Formation by Targeting Key Transporters in Hepatobiliary Cholesterol Secretion Pathway.

International journal of biological sciences

Zhao F,Ma S,Zhou Y,Wei B,Hao Z,Cui X,Xing L,Liu G,Jin L,Ma T,Shi L

Mon Dec 20 00:00:00 UTC 2021

Autographa Californica Multiple Nucleopolyhedrovirus orf13 Is Required for Efficient Nuclear Egress of Nucleocapsids.

Virologica Sinica

Chen X,Yang X,Lei C,Qin F,Sun X,Hu J

Fri Oct 01 00:00:00 UTC 2021

Cytoplasmic polyadenylation by TENT5A is required for proper bone formation.

Cell reports

Gewartowska O,Aranaz-Novaliches G,Krawczyk PS,Mroczek S,Kusio-Kobiałka M,Tarkowski B,Spoutil F,Benada O,Kofroňová O,Szwedziak P,Cysewski D,Gruchota J,Szpila M,Chlebowski A,Sedlacek R,Prochazka J,Dziembowski A

Tue Apr 20 00:00:00 UTC 2021

Cytoplasmic polyadenylation by TENT5A is required for proper bone formation.

Cell reports

Tue Apr 20 00:00:00 UTC 2021

African Swine Fever Virus MGF360-12L Inhibits Type I Interferon Production by Blocking the Interaction of Importin α and NF-κB Signaling Pathway.

Virologica Sinica

Zhuo Y,Guo Z,Ba T,Zhang C,He L,Zeng C,Dai H

Thu Apr 01 00:00:00 UTC 2021

African Swine Fever Virus MGF360-12L Inhibits Type I Interferon Production by Blocking the Interaction of Importin α and NF-κB Signaling Pathway.

Virologica Sinica

Zhuo Y,Guo Z,Ba T,Zhang C,He L,Zeng C,Dai H

Thu Apr 01 00:00:00 UTC 2021

African Swine Fever Virus MGF360-12L Inhibits Type I Interferon Production by Blocking the Interaction of Importin α and NF-κB Signaling Pathway.

Virologica Sinica

Zhuo Y,Guo Z,Ba T,Zhang C,He L,Zeng C,Dai H

Thu Apr 01 00:00:00 UTC 2021

Long non-coding RNA AC122108.1 promotes lung adenocarcinoma brain metastasis and progression through the Wnt/β-catenin pathway by directly binding to aldolase A.

Annals of translational medicine

Feng S,Liu H,Du P,Dong X,Pang Q,Guo H

Wed Dec 01 00:00:00 UTC 2021

High-Throughput Amenable MALDI-MS Detection of RNA and DNA with On-Surface Analyte Enrichment Using Fluorous Partitioning.

SLAS discovery : advancing life sciences R & D

Emanuelson C,Ankenbruck N,Deiters A,Yu MS

Fri Jan 01 00:00:00 UTC 2021

Hepatitis B Virus Core Protein Mediates the Upregulation of C5α Receptor 1 via NF-κB Pathway to Facilitate the Growth and Migration of Hepatoma Cells.

Cancer research and treatment

Kong F,Tao Y,Yuan D,Zhang N,Li Q,Yu T,Yang X,Kong D,Ding X,Liu X,You H,Zheng K,Tang R

Thu Apr 01 00:00:00 UTC 2021

YWHAZ interacts with DAAM1 to promote cell migration in breast cancer.

Cell death discovery

Mei J,Liu Y,Yu X,Hao L,Ma T,Zhan Q,Zhang Y,Zhu Y

Fri Aug 27 00:00:00 UTC 2021

YWHAZ interacts with DAAM1 to promote cell migration in breast cancer.

Cell death discovery

Mei J,Liu Y,Yu X,Hao L,Ma T,Zhan Q,Zhang Y,Zhu Y

Fri Aug 27 00:00:00 UTC 2021

TIPE1 Suppresses Growth and Metastasis of Ovarian Cancer.

Journal of oncology

Zhang Z,Chang M,Song X,Wang K,Sun W,Ma H,Yan X,Sun Y,Song X,Xie L

Thu Jul 01 00:00:00 UTC 2021

OTUD6A Is an Aurora Kinase A-Specific Deubiquitinase.

International journal of molecular sciences

Kim HJ,Kim J

Tue Feb 16 00:00:00 UTC 2021

TULP2, a New RNA-Binding Protein, Is Required for Mouse Spermatid Differentiation and Male Fertility.

Frontiers in cell and developmental biology

Zheng M,Chen X,Cui Y,Li W,Dai H,Yue Q,Zhang H,Zheng Y,Guo X,Zhu H

Fri Mar 26 00:00:00 UTC 2021

In situ detection of protein interactions for recombinant therapeutic enzymes.

Biotechnology and bioengineering

Samoudi M,Kuo CC,Robinson CM,Shams-Ud-Doha K,Schinn SM,Kol S,Weiss L,Petersen Bjorn S,Voldborg BG,Rosa Campos A,Lewis NE

Mon Feb 01 00:00:00 UTC 2021

Interferon functional analog activates antiviral Jak/Stat signaling through integrin in an arthropod.

Cell reports

Gao J,Zhao BR,Zhang H,You YL,Li F,Wang XW

Tue Sep 28 00:00:00 UTC 2021

miR-26a enhances colorectal cancer cell growth by targeting RREB1 deacetylation to activate AKT-mediated glycolysis.

Cancer letters

Chen B,Deng YN,Wang X,Xia Z,He Y,Zhang P,Syed SE,Li Q,Liang S

Thu Aug 19 00:00:00 UTC 2021

Lipid droplets contribute myogenic differentiation in C2C12 by promoting the remodeling of the acstin-filament.

Cell death & disease

Tan Y,Jin Y,Zhao P,Wu J,Ren Z

Tue Nov 23 00:00:00 UTC 2021

TLR4 signalling via Piezo1 engages and enhances the macrophage mediated host response during bacterial infection.

Nature communications

Geng J,Shi Y,Zhang J,Yang B,Wang P,Yuan W,Zhao H,Li J,Qin F,Hong L,Xie C,Deng X,Sun Y,Wu C,Chen L,Zhou D

Thu Jun 10 00:00:00 UTC 2021

Crystal structures reveal a novel dimer of the RWD domain of human general control nonderepressible 2.

Biochemical and biophysical research communications

Hei Z,Wu S,Zheng L,Zhou J,Liu Z,Wang J,Fang P

Fri Apr 16 00:00:00 UTC 2021

Potent Inhibition of HIF1α and p300 Interaction by a Constrained Peptide Derived from CITED2.

Journal of medicinal chemistry

Qin X,Chen H,Tu L,Ma Y,Liu N,Zhang H,Li D,Riedl B,Bierer D,Yin F,Li Z

Thu Sep 23 00:00:00 UTC 2021

Potent Inhibition of HIF1α and p300 Interaction by a Constrained Peptide Derived from CITED2.

Journal of medicinal chemistry

Qin X,Chen H,Tu L,Ma Y,Liu N,Zhang H,Li D,Riedl B,Bierer D,Yin F,Li Z

Thu Sep 23 00:00:00 UTC 2021

Efficient expression of heterologous genes by the introduction of the endogenous glyceraldehyde-3-phosphate dehydrogenase gene intron 1 in Ganoderma lucidum.

Microbial cell factories

You H,Sun B,Li N,Xu JW

Sat Aug 21 00:00:00 UTC 2021

Echinatin effectively protects against NLRP3 inflammasome-driven diseases by targeting HSP90.

JCI insight

Xu G,Fu S,Zhan X,Wang Z,Zhang P,Shi W,Qin N,Chen Y,Wang C,Niu M,Guo Y,Wang J,Bai Z,Xiao X

Mon Jan 25 00:00:00 UTC 2021

NLGN3 Upregulates Expression of ADAM10 to Promote the Cleavage of NLGN3 via Activating the LYN Pathway in Human Gliomas.

Frontiers in cell and developmental biology

Dang NN,Li XB,Zhang M,Han C,Fan XY,Huang SH

Tue Sep 07 00:00:00 UTC 2021

Expression and Purification of Yeast-derived GPCR, Gα and Gβγ Subunits for Structural and Dynamic Studies.

Bio-protocol

Zhao W,Wang X,Ye L

Sat Feb 20 00:00:00 UTC 2021

Nedd4-2 haploinsufficiency in mice causes increased seizure susceptibility and impaired Kir4.1 ubiquitination.

Biochimica et biophysica acta. Molecular basis of disease

Liu X,Zhang H,Zhang B,Tu J,Li X,Zhao Y

Tue Jun 01 00:00:00 UTC 2021

Mutation analysis of MFSD8 in an amyotrophic lateral sclerosis cohort from mainland China.

The European journal of neuroscience

Huang L,Liu Z,Yuan Y,Shen L,Jiang H,Tang B,Wang J,Lei L

Mon Feb 01 00:00:00 UTC 2021

PTEN alleviates maladaptive repair of renal tubular epithelial cells by restoring CHMP2A-mediated phagosome closure.

Cell death & disease

Wang H,Wang Y,Wang X,Huang H,Bao J,Zhong W,Li A

Tue Nov 16 00:00:00 UTC 2021

CHIP-mediated CIB1 ubiquitination regulated epithelial-mesenchymal transition and tumor metastasis in lung adenocarcinoma.

Cell death and differentiation

Liu Y,Zhou Y,Zhang P,Li X,Duan C,Zhang C

Mon Mar 01 00:00:00 UTC 2021

KIF15 upregulation promotes leiomyosarcoma cell growth via promoting USP15-mediated DEK deubiquitylation.

Biochemical and biophysical research communications

Ge W,Chen Y,Guo Y,Zhao D,Mu L,Zhang K,Zhuo W

Fri Sep 17 00:00:00 UTC 2021

Self-stabilizing regulation of deubiquitinating enzymes in an enzymatic activity-dependent manner.

International journal of biological macromolecules

Hou Z,Shi W,Feng J,Wang W,Zheng E,Lin H,Yu C,Li L

Wed Jun 30 00:00:00 UTC 2021

IKKε isoform switching governs the immune response against EV71 infection.

Communications biology

Chang YL,Liao YW,Chen MH,Chang SY,Huang YT,Ho BC,Yu SL

Wed Jun 02 00:00:00 UTC 2021

Characterization of a Cohort of Patients With LIG4 Deficiency Reveals the Founder Effect of p.R278L, Unique to the Chinese Population.

Frontiers in immunology

Luo X,Liu Q,Jiang J,Tang W,Ding Y,Zhou L,Yu J,Tang X,An Y,Zhao X

Mon Dec 13 00:00:00 UTC 2021

Octamer transcription factor-1 induces the Warburg effect via up-regulation of hexokinase 2 in non-small cell lung cancer.

Molecular and cellular biochemistry

Li Z,Su J,Sun M,Song J,Sun H,Fan J,Chen G,Shan C,Qi Q,Zhang S

Wed Sep 01 00:00:00 UTC 2021

GLIS Family Zinc Finger 1 was First Linked With Preaxial Polydactyly I in Humans by Stepwise Genetic Analysis.

Frontiers in cell and developmental biology

Jin JY,Wu PF,Luo FM,Guo BB,Zeng L,Fan LL,Tang JY,Xiang R

Sat Jan 29 00:00:00 UTC 2022

GLIS Family Zinc Finger 1 was First Linked With Preaxial Polydactyly I in Humans by Stepwise Genetic Analysis.

Frontiers in cell and developmental biology

Jin JY,Wu PF,Luo FM,Guo BB,Zeng L,Fan LL,Tang JY,Xiang R

Sat Jan 29 00:00:00 UTC 2022

Deubiquitinase USP35 restrains STING-mediated interferon signaling in ovarian cancer.

Cell death and differentiation

Zhang J,Chen Y,Chen X,Zhang W,Zhao L,Weng L,Tian H,Wu Z,Tan X,Ge X,Wang P,Fang L

Fri Jan 01 00:00:00 UTC 2021

YB1 regulates miR-205/200b-ZEB1 axis by inhibiting microRNA maturation in hepatocellular carcinoma.

Cancer communications (London, England)

Liu X,Chen D,Chen H,Wang W,Liu Y,Wang Y,Duan C,Ning Z,Guo X,Otkur W,Liu J,Qi H,Liu X,Lin A,Xia T,Liu HX,Piao HL

Thu Jul 01 00:00:00 UTC 2021

Two loss-of-function ANKRD11 variants in Chinese patients with short stature and a possible molecular pathway.

American journal of medical genetics. Part A

Zhang T,Yang Y,Yin X,Wang X,Ni J,Dong Z,Li C,Lu W

Mon Mar 01 00:00:00 UTC 2021

Insertion of Exogenous Genes within the ORF1a Coding Region of Porcine Astrovirus.

Viruses

Du Y,Liu T,Qin Y,Dong Q,Chen Y,Ouyang K,Wei Z,Huang W

Thu Oct 21 00:00:00 UTC 2021

A dual-role of SARS-CoV-2 nucleocapsid protein in regulating innate immune response.

Signal transduction and targeted therapy

Zhao Y,Sui L,Wu P,Wang W,Wang Z,Yu Y,Hou Z,Tan G,Liu Q,Wang G

Wed Sep 01 00:00:00 UTC 2021

A dual-role of SARS-CoV-2 nucleocapsid protein in regulating innate immune response.

Signal transduction and targeted therapy

Zhao Y,Sui L,Wu P,Wang W,Wang Z,Yu Y,Hou Z,Tan G,Liu Q,Wang G

Wed Sep 01 00:00:00 UTC 2021

A dual-role of SARS-CoV-2 nucleocapsid protein in regulating innate immune response.

Signal transduction and targeted therapy

Zhao Y,Sui L,Wu P,Wang W,Wang Z,Yu Y,Hou Z,Tan G,Liu Q,Wang G

Wed Sep 01 00:00:00 UTC 2021

Suppression of DLBCL Progression by the E3 Ligase Trim35 Is Mediated by CLOCK Degradation and NK Cell Infiltration.

Journal of immunology research

Tan X,Cao F,Tang F,Lu C,Yu Q,Feng S,Yang Z,Chen S,He X,He J,Weng L,Sun L

Mon Dec 20 00:00:00 UTC 2021

Medioresinol as a novel PGC-1α activator prevents pyroptosis of endothelial cells in ischemic stroke through PPARα-GOT1 axis.

Pharmacological research

Wang Y,Guan X,Gao CL,Ruan W,Zhao S,Kai G,Li F,Pang T

Thu Jul 01 00:00:00 UTC 2021

Arsenic trioxide induces macrophage autophagy and atheroprotection by regulating ROS-dependent TFEB nuclear translocation and AKT/mTOR pathway.

Cell death & disease

Fang S,Wan X,Zou X,Sun S,Hao X,Liang C,Zhang Z,Zhang F,Sun B,Li H,Yu B

Mon Jan 18 00:00:00 UTC 2021

The mitochondrial protein ERAL1 suppresses RNA virus infection by facilitating RIG-I-like receptor signaling.

Cell reports

Li S,Kuang M,Chen L,Li Y,Liu S,Du H,Cao L,You F

Tue Jan 19 00:00:00 UTC 2021

SARS-CoV-2 Nsp5 Activates NF-κB Pathway by Upregulating SUMOylation of MAVS.

Frontiers in immunology

Li W,Qiao J,You Q,Zong S,Peng Q,Liu Y,Hu S,Liu W,Li S,Shu X,Sun B

Tue Dec 14 00:00:00 UTC 2021

Discovery of a Novel MyD88 Inhibitor M20 and Its Protection Against Sepsis-Mediated Acute Lung Injury.

Frontiers in pharmacology

Song J,Chen D,Pan Y,Shi X,Liu Q,Lu X,Xu X,Chen G,Cai Y

Fri Dec 17 00:00:00 UTC 2021

RABL2A-CCDC34 Axis Promotes Sorafenib Resistance in Hepatocellular Carcinoma.

DNA and cell biology

Zhou M,Chen X,Bai H,Sun Y,Zhang Z,Li S,Wang X,Zeng M

Mon Nov 01 00:00:00 UTC 2021

LHX9, a p53-binding protein, inhibits the progression of glioma by suppressing glycolysis.

Aging

Luo X,Ge J,Chen T,Liu J,Liu Z,Bi C,Lan S

Fri Sep 17 00:00:00 UTC 2021

E3 ligase TRIM25 ubiquitinates RIP3 to inhibit TNF induced cell necrosis.

Cell death and differentiation

Mei P,Xie F,Pan J,Wang S,Gao W,Ge R,Gao B,Gao S,Chen X,Wang Y,Wu J,Ding C,Li J

Fri Oct 01 00:00:00 UTC 2021

CircURI1 interacts with hnRNPM to inhibit metastasis by modulating alternative splicing in gastric cancer.

Proceedings of the National Academy of Sciences of the United States of America

Wang X,Li J,Bian X,Wu C,Hua J,Chang S,Yu T,Li H,Li Y,Hu S,Shan G,Lin W

Tue Aug 17 00:00:00 UTC 2021

The tyrosine phosphatase SHP-2 dephosphorylated by ALV-J via its Env efficiently promotes ALV-J replication.

Virulence

Li T,Xie J,Yao X,Zhang J,Li C,Ren D,Li L,Xie Q,Shao H,Qin A,Ye J

Wed Dec 01 00:00:00 UTC 2021

TNPO1-Mediated Nuclear Import of FUBP1 Contributes to Tumor Immune Evasion by Increasing NRP1 Expression in Cervical Cancer.

Journal of immunology research

Yang B,Chen J,Teng Y

Mon Nov 29 00:00:00 UTC 2021

SUMOylation- and GAR1-Dependent Regulation of Dyskerin Nuclear and Subnuclear Localization.

Molecular and cellular biology

MacNeil DE,Lambert-Lanteigne P,Qin J,McManus FP,Bonneil E,Thibault P,Autexier C

Wed Mar 24 00:00:00 UTC 2021

TRIM15 promotes the invasion and metastasis of pancreatic cancer cells by mediating APOA1 ubiquitination and degradation.

Biochimica et biophysica acta. Molecular basis of disease

Sun Y,Ren D,Yang C,Yang W,Zhao J,Zhou Y,Jin X,Wu H

Mon Nov 01 00:00:00 UTC 2021

Regulation of survivin protein stability by USP35 is evolutionarily conserved.

Biochemical and biophysical research communications

Wang W,Lin H,Zheng E,Hou Z,Liu Y,Huang W,Chen D,Feng J,Li J,Li L

Fri Oct 15 00:00:00 UTC 2021

Regulation of survivin protein stability by USP35 is evolutionarily conserved.

Biochemical and biophysical research communications

Wang W,Lin H,Zheng E,Hou Z,Liu Y,Huang W,Chen D,Feng J,Li J,Li L

Fri Oct 15 00:00:00 UTC 2021

Loss of TACC1 variant25 inducing cell proliferation and suppressing autophagy in head and neck squamous carcinoma.

Cell death discovery

Xu P,Zhao R,Zhang CY,Zhang QQ,Wang Y,Zhu J,Jiang WW

Sat Dec 11 00:00:00 UTC 2021

ZNF213 Facilitates ER Alpha Signaling in Breast Cancer Cells.

Frontiers in oncology

Yang H,Lv X,Li X,Mao L,Niu Z,Wang T,Zhuang T,Huang Q

Thu Apr 21 00:00:00 UTC 2022

Aldehyde Dehydrogenase 2 Mediates Alcohol-Induced Colorectal Cancer Immune Escape through Stabilizing PD-L1 Expression.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Zhang H,Xia Y,Wang F,Luo M,Yang K,Liang S,An S,Wu S,Yang C,Chen D,Xu M,Cai M,To KKW,Fu L

Sat May 01 00:00:00 UTC 2021

LncRNA MALAT1 was regulated by HPV16 E7 independently of pRB in cervical cancer cells.

Journal of Cancer

Wang T,Zhang W,Huang W,Hua Z,Li S

Fri Oct 22 00:00:00 UTC 2021

LncRNA MALAT1 was regulated by HPV16 E7 independently of pRB in cervical cancer cells.

Journal of Cancer

Wang T,Zhang W,Huang W,Hua Z,Li S

Fri Oct 22 00:00:00 UTC 2021

Structural mechanism of bivalent histone H3K4me3K9me3 recognition by the Spindlin1/C11orf84 complex in rRNA transcription activation.

Nature communications

Du Y,Yan Y,Xie S,Huang H,Wang X,Ng RK,Zhou MM,Qian C

Thu Feb 11 00:00:00 UTC 2021

Sulfation of a FLAG tag mediated by SLC35B2 and TPST2 affects antibody recognition.

PloS one

Guo XY,Gao XD,Fujita M

Mon Oct 18 00:00:00 UTC 2021

Genome-scale CRISPR screen identifies TMEM41B as a multi-function host factor required for coronavirus replication.

PLoS pathogens

Sun L,Zhao C,Fu Z,Fu Y,Su Z,Li Y,Zhou Y,Tan Y,Li J,Xiang Y,Nie X,Zhang J,Liu F,Zhao S,Xie S,Peng G

Wed Dec 01 00:00:00 UTC 2021

Deubiquitination of MITF-M Regulates Melanocytes Proliferation and Apoptosis.

Frontiers in molecular biosciences

Hu S,Bai S,Dai Y,Yang N,Li J,Zhang X,Wang F,Zhao B,Bao G,Chen Y,Wu X

Tue Jun 29 00:00:00 UTC 2021

A novel mutation in NF1 gene of patient with Neurofibromatosis type 1: A case report and functional study.

Molecular genetics & genomic medicine

Zhang T,Jia C,Dong Z,Li C,Lu W

Sat May 01 00:00:00 UTC 2021

Quantitative proteomics identifies PTP1B as modulator of B cell antigen receptor signaling.

Life science alliance

Schwarz JJ,Grundmann L,Kokot T,Kläsener K,Fotteler S,Medgyesi D,Köhn M,Reth M,Warscheid B

Mon Nov 01 00:00:00 UTC 2021

Quantitative proteomics identifies PTP1B as modulator of B cell antigen receptor signaling.

Life science alliance

Schwarz JJ,Grundmann L,Kokot T,Kläsener K,Fotteler S,Medgyesi D,Köhn M,Reth M,Warscheid B

Mon Nov 01 00:00:00 UTC 2021

ZBTB38 suppresses prostate cancer cell proliferation and migration via directly promoting DKK1 expression.

Cell death & disease

Ding G,Lu W,Zhang Q,Li K,Zhou H,Wang F,Zhao C,Fan C,Wang J

Mon Oct 25 00:00:00 UTC 2021

ZBTB38 suppresses prostate cancer cell proliferation and migration via directly promoting DKK1 expression.

Cell death & disease

Ding G,Lu W,Zhang Q,Li K,Zhou H,Wang F,Zhao C,Fan C,Wang J

Mon Oct 25 00:00:00 UTC 2021

ATPAF1 deficiency impairs ATP synthase assembly and mitochondrial respiration.

Mitochondrion

Zhou Z,Zhang K,Liu Z,Gao X,Huang K,Chen C,Wang D,Yang Q,Long Q

Wed Sep 01 00:00:00 UTC 2021

Characterization of Two Loss-of-Function NF1 Variants in Chinese Patients and Potential Molecular Interpretations of Phenotypes.

Frontiers in genetics

Zhang T,Han T,Dong Z,Li C,Lu W

Sun May 30 00:00:00 UTC 2021

Characterization of Two Loss-of-Function NF1 Variants in Chinese Patients and Potential Molecular Interpretations of Phenotypes.

Frontiers in genetics

Zhang T,Han T,Dong Z,Li C,Lu W

Sun May 30 00:00:00 UTC 2021

Chaperone-mediated autophagy controls the turnover of E3 ubiquitin ligase MARCHF5 and regulates mitochondrial dynamics.

Autophagy

Nie T,Tao K,Zhu L,Huang L,Hu S,Yang R,Xu P,Mao Z,Yang Q

Fri Oct 01 00:00:00 UTC 2021

Chaperone-mediated autophagy controls the turnover of E3 ubiquitin ligase MARCHF5 and regulates mitochondrial dynamics.

Autophagy

Nie T,Tao K,Zhu L,Huang L,Hu S,Yang R,Xu P,Mao Z,Yang Q

Fri Oct 01 00:00:00 UTC 2021

Ca²⁺ sensor-mediated ROS scavenging suppresses rice immunity and is exploited by a fungal effector.

Cell

Gao M,He Y,Yin X,Zhong X,Yan B,Wu Y,Chen J,Li X,Zhai K,Huang Y,Gong X,Chang H,Xie S,Liu J,Yue J,Xu J,Zhang G,Deng Y,Wang E,Tharreau D,Wang GL,Yang W,He Z

Thu Oct 14 00:00:00 UTC 2021

Degradation of WTAP blocks antiviral responses by reducing the m⁶ A levels of IRF3 and IFNAR1 mRNA.

EMBO reports

Ge Y,Ling T,Wang Y,Jia X,Xie X,Chen R,Chen S,Yuan S,Xu A

Thu Nov 04 00:00:00 UTC 2021

Asparagine endopeptidase cleaves synaptojanin 1 and triggers synaptic dysfunction in Parkinson's disease.

Neurobiology of disease

Zou L,Zhang X,Xiong M,Meng L,Tian Y,Pan L,Yuan X,Chen G,Wang Z,Bu L,Yao Z,Zhang Z,Ye K,Zhang Z

Thu Jul 01 00:00:00 UTC 2021

Proximity Labeling, Quantitative Proteomics, and Biochemical Studies Revealed the Molecular Mechanism for the Inhibitory Effect of Indisulam on the Proliferation of Gastric Cancer Cells.

Journal of proteome research

Lu J,Jiang H,Li D,Chen T,Wang Y,Pu Z,Xu G

Fri Sep 03 00:00:00 UTC 2021

USP29 coordinates MYC and HIF1α stabilization to promote tumor metabolism and progression.

Oncogene

Tu R,Kang W,Yang M,Wang L,Bao Q,Chen Z,Dong Y,Wang J,Jiang J,Liu H,Qing G

Mon Nov 01 00:00:00 UTC 2021

Crystal structure of the PDZ4 domain of MAGI2 in complex with PBM of ARMS reveals a canonical PDZ recognition mode.

Neurochemistry international

Zhang Y,Zhong Z,Ye J,Wang C

Fri Oct 01 00:00:00 UTC 2021

KAT2A-mediated AR translocation into nucleus promotes abiraterone-resistance in castration-resistant prostate cancer.

Cell death & disease

Lu D,Song Y,Yu Y,Wang D,Liu B,Chen L,Li X,Li Y,Cheng L,Lv F,Zhang P,Xing Y

Thu Aug 12 00:00:00 UTC 2021

Bovine viral diarrhea virus NS4B protein interacts with 2CARD of MDA5 domain and negatively regulates the RLR-mediated IFN-β production.

Virus research

Shan Y,Tong Z,Jinzhu M,Yu L,Zecai Z,Chenhua W,Wenjing H,Siyu L,Nannan C,Siyu S,Tongtong B,Jiang H,Biaohui B,Xin J,Yulong Z,Zhanbo Z

Wed Sep 01 00:00:00 UTC 2021

Identification of the atypical cadherin FAT1 as a novel glypican-3 interacting protein in liver cancer cells.

Scientific reports

Meng P,Zhang YF,Zhang W,Chen X,Xu T,Hu S,Liang X,Feng M,Yang X,Ho M

Fri Jan 08 00:00:00 UTC 2021

Identification of the atypical cadherin FAT1 as a novel glypican-3 interacting protein in liver cancer cells.

Scientific reports

Meng P,Zhang YF,Zhang W,Chen X,Xu T,Hu S,Liang X,Feng M,Yang X,Ho M

Fri Jan 08 00:00:00 UTC 2021

Positive regulation of PFKFB3 by PIM2 promotes glycolysis and paclitaxel resistance in breast cancer.

Clinical and translational medicine

Lu C,Qiao P,Sun Y,Ren C,Yu Z

Thu Apr 01 00:00:00 UTC 2021

Positive regulation of PFKFB3 by PIM2 promotes glycolysis and paclitaxel resistance in breast cancer.

Clinical and translational medicine

Lu C,Qiao P,Sun Y,Ren C,Yu Z

Thu Apr 01 00:00:00 UTC 2021

PIKE-A promotes glioblastoma growth by driving PPP flux through increasing G6PD expression mediated by phosphorylation of STAT3.

Biochemical pharmacology

Sun M,Sheng H,Wu T,Song J,Sun H,Wang Y,Wang J,Li Z,Zhao H,Tan J,Li Y,Chen G,Huang Q,Zhang Y,Lan B,Liu S,Shan C,Zhang S

Fri Oct 01 00:00:00 UTC 2021

PIKE-A promotes glioblastoma growth by driving PPP flux through increasing G6PD expression mediated by phosphorylation of STAT3.

Biochemical pharmacology

Sun M,Sheng H,Wu T,Song J,Sun H,Wang Y,Wang J,Li Z,Zhao H,Tan J,Li Y,Chen G,Huang Q,Zhang Y,Lan B,Liu S,Shan C,Zhang S

Fri Oct 01 00:00:00 UTC 2021

Circular RNA circRHOBTB3 represses metastasis by regulating the HuR-mediated mRNA stability of PTBP1 in colorectal cancer.

Theranostics

Chen J,Wu Y,Luo X,Jin D,Zhou W,Ju Z,Wang D,Meng Q,Wang H,Fu X,Xu J,Song Z

Wed Jul 28 00:00:00 UTC 2021

Histone acetyltransferase 1 promotes gemcitabine resistance by regulating the PVT1/EZH2 complex in pancreatic cancer.

Cell death & disease

Sun Y,Ren D,Zhou Y,Shen J,Wu H,Jin X

Sat Sep 25 00:00:00 UTC 2021

SARS-CoV-2 nucleocapsid protein phase separates with G3BPs to disassemble stress granules and facilitate viral production.

Science bulletin

Luo L,Li Z,Zhao T,Ju X,Ma P,Jin B,Zhou Y,He S,Huang J,Xu X,Zou Y,Li P,Liang A,Liu J,Chi T,Huang X,Ding Q,Jin Z,Huang C,Zhang Y

Wed Jun 30 00:00:00 UTC 2021

SARS-CoV-2 nucleocapsid protein phase separates with G3BPs to disassemble stress granules and facilitate viral production.

Science bulletin

Luo L,Li Z,Zhao T,Ju X,Ma P,Jin B,Zhou Y,He S,Huang J,Xu X,Zou Y,Li P,Liang A,Liu J,Chi T,Huang X,Ding Q,Jin Z,Huang C,Zhang Y

Wed Jun 30 00:00:00 UTC 2021

Inhibition of SENP2-mediated Akt deSUMOylation promotes cardiac regeneration via activating Akt pathway.

Clinical science (London, England : 1979)

Chen Y,Xu T,Li M,Li C,Ma Y,Chen G,Sun Y,Zheng H,Wu G,Liao W,Liao Y,Chen Y,Bin J

Fri Mar 26 00:00:00 UTC 2021

IL1RN promotes osteoblastic differentiation via interacting with ITGB3 in osteoporosis.

Acta biochimica et biophysica Sinica

Zou Z,Liu R,Wang Y,Xing Y,Shi Z,Wang K,Dong D

Tue Mar 02 00:00:00 UTC 2021

Novel SREBP1 inhibitor cinobufotalin suppresses proliferation of hepatocellular carcinoma by targeting lipogenesis.

European journal of pharmacology

Meng H,Shen M,Li J,Zhang R,Li X,Zhao L,Huang G,Liu J

Sun Sep 05 00:00:00 UTC 2021

Melatonin functions in priming of stomatal immunity in Panax notoginseng and Arabidopsis thaliana.

Plant physiology

Yang Q,Peng Z,Ma W,Zhang S,Hou S,Wei J,Dong S,Yu X,Song Y,Gao W,Rengel Z,Huang L,Cui X,Chen Q

Sat Dec 04 00:00:00 UTC 2021

Melatonin functions in priming of stomatal immunity in Panax notoginseng and Arabidopsis thaliana.

Plant physiology

Yang Q,Peng Z,Ma W,Zhang S,Hou S,Wei J,Dong S,Yu X,Song Y,Gao W,Rengel Z,Huang L,Cui X,Chen Q

Sat Dec 04 00:00:00 UTC 2021

Molecular basis for recognition of Gly/N-degrons by CRL2^ZYG11B and CRL2^ZER1.

Molecular cell

Yan X,Li Y,Wang G,Zhou Z,Song G,Feng Q,Zhao Y,Mi W,Ma Z,Dong C

Thu Aug 19 00:00:00 UTC 2021

HRD1 inhibits fatty acid oxidation and tumorigenesis by ubiquitinating CPT2 in triple-negative breast cancer.

Molecular oncology

Guo X,Wang A,Wang W,Wang Y,Chen H,Liu X,Xia T,Zhang A,Chen D,Qi H,Ling T,Piao HL,Wang HJ

Mon Feb 01 00:00:00 UTC 2021

HRD1 inhibits fatty acid oxidation and tumorigenesis by ubiquitinating CPT2 in triple-negative breast cancer.

Molecular oncology

Guo X,Wang A,Wang W,Wang Y,Chen H,Liu X,Xia T,Zhang A,Chen D,Qi H,Ling T,Piao HL,Wang HJ

Mon Feb 01 00:00:00 UTC 2021

Two Novel Hydroxymethylbilane Synthase Splicing Mutations Predispose to Acute Intermittent Porphyria.

International journal of molecular sciences

Zhang Y,Xiao H,Xiong Q,Wu C,Li P

Tue Oct 12 00:00:00 UTC 2021

A Cas9-transcription factor fusion protein enhances homology-directed repair efficiency.

The Journal of biological chemistry

Li G,Wang H,Zhang X,Wu Z,Yang H

Fri Aug 20 00:00:00 UTC 2021

A Cas9-transcription factor fusion protein enhances homology-directed repair efficiency.

The Journal of biological chemistry

Li G,Wang H,Zhang X,Wu Z,Yang H

Fri Aug 20 00:00:00 UTC 2021

TDP-43 and PINK1 mediate CHCHD10^S59L mutation-induced defects in Drosophila and in vitro.

Nature communications

Baek M,Choe YJ,Bannwarth S,Kim J,Maitra S,Dorn GW,Taylor JP,Paquis-Flucklinger V,Kim NC

Fri Mar 26 00:00:00 UTC 2021

Knockdown of NIR Suppresses Breast Cancer Cell Proliferation via Promoting FOXO3.

OncoTargets and therapy

Chen B,Dong C,Wang F,Wu J

Wed Apr 20 00:00:00 UTC 2022

Transcriptomic Profiling Reveals a Role for TREM-1 Activation in Enterovirus D68 Infection-Induced Proinflammatory Responses.

Frontiers in immunology

Li J,Yang S,Liu S,Chen Y,Liu H,Su Y,Liu R,Cui Y,Song Y,Teng Y,Wang T

Tue Dec 21 00:00:00 UTC 2021

Role of clusterin in the regulation of trophoblast development and preeclampsia.

Biochemical and biophysical research communications

Zeng S,Pan Y,Liu F,Yin J,Jiang M,Long Y,Zhao X,Lash GE,Yang H

Sat Oct 30 00:00:00 UTC 2021

Glutamyl-Prolyl-tRNA Synthetase Regulates Proline-Rich Pro-Fibrotic Protein Synthesis During Cardiac Fibrosis.

Circulation research

Wu J,Subbaiah KCV,Xie LH,Jiang F,Khor ES,Mickelsen D,Myers JR,Tang WHW,Yao P

Fri Aug 28 00:00:00 UTC 2020

TMEM59 Haploinsufficiency Ameliorates the Pathology and Cognitive Impairment in the 5xFAD Mouse Model of Alzheimer's Disease.

Frontiers in cell and developmental biology

Meng J,Han L,Zheng N,Xu H,Liu Z,Zhang X,Luo H,Can D,Sun H,Xu H,Zhang YW

Tue Nov 17 00:00:00 UTC 2020

PCDH7 Inhibits the Formation of Homotypic Cell-in-Cell Structure.

Frontiers in cell and developmental biology

Wang C,Chen A,Ruan B,Niu Z,Su Y,Qin H,Zheng Y,Zhang B,Gao L,Chen Z,Huang H,Wang X,Sun Q

Mon Sep 28 00:00:00 UTC 2020

Shikonin blocks human lung adenocarcinoma cell migration and invasion in the inflammatory microenvironment via the IL‑6/STAT3 signaling pathway.

Oncology reports

Pan T,Zhang F,Li F,Gao X,Li Z,Li X,Ren X

Tue Sep 01 00:00:00 UTC 2020

Interdependent YpsA- and YfhS-Mediated Cell Division and Cell Size Phenotypes in Bacillus subtilis.

mSphere

Brzozowski RS,Tomlinson BR,Sacco MD,Chen JJ,Ali AN,Chen Y,Shaw LN,Eswara PJ

Wed Jul 22 00:00:00 UTC 2020

Tethering of Telomeres to the Nuclear Envelope Is Mediated by SUN1-MAJIN and Possibly Promoted by SPDYA-CDK2 During Meiosis.

Frontiers in cell and developmental biology

Wang G,Wu X,Zhou L,Gao S,Yun D,Liang A,Sun F

Tue Oct 06 00:00:00 UTC 2020

Tethering of Telomeres to the Nuclear Envelope Is Mediated by SUN1-MAJIN and Possibly Promoted by SPDYA-CDK2 During Meiosis.

Frontiers in cell and developmental biology

Wang G,Wu X,Zhou L,Gao S,Yun D,Liang A,Sun F

Tue Oct 06 00:00:00 UTC 2020

Deubiquitinase USP13 promotes extracellular matrix expression by stabilizing Smad4 in lung fibroblast cells.

Translational research : the journal of laboratory and clinical medicine

Liao X,Li Y,Liu J,Zhang Y,Tan J,Kass DJ,Rojas M,Mallampalli RK,Zhao J,Zhao Y

Tue Sep 01 00:00:00 UTC 2020

LncRNA TROJAN promotes proliferation and resistance to CDK4/6 inhibitor via CDK2 transcriptional activation in ER+ breast cancer.

Molecular cancer

Jin X,Ge LP,Li DQ,Shao ZM,Di GH,Xu XE,Jiang YZ

Mon May 11 00:00:00 UTC 2020

LncRNA TROJAN promotes proliferation and resistance to CDK4/6 inhibitor via CDK2 transcriptional activation in ER+ breast cancer.

Molecular cancer

Jin X,Ge LP,Li DQ,Shao ZM,Di GH,Xu XE,Jiang YZ

Mon May 11 00:00:00 UTC 2020

LncRNA TROJAN promotes proliferation and resistance to CDK4/6 inhibitor via CDK2 transcriptional activation in ER+ breast cancer.

Molecular cancer

Jin X,Ge LP,Li DQ,Shao ZM,Di GH,Xu XE,Jiang YZ

Mon May 11 00:00:00 UTC 2020

Multivesicular body sorting and the exosomal pathway are required for the release of rat hepatitis E virus from infected cells.

Virus research

Primadharsini PP,Nagashima S,Takahashi M,Kobayashi T,Nishiyama T,Nishizawa T,Yasuda J,Okamoto H

Sun Mar 01 00:00:00 UTC 2020

microRNA-421-3p prevents inflammatory response in cerebral ischemia/reperfusion injury through targeting m6A Reader YTHDF1 to inhibit p65 mRNA translation.

International immunopharmacology

Zheng L,Tang X,Lu M,Sun S,Xie S,Cai J,Zan J

Sun Nov 01 00:00:00 UTC 2020

Functional Analysis of Steroidogenic Factor 1 (sf-1) and 17α-Hydroxylase/Lyase (cyp17α) Promoters in Yellow Catfish Pelteobagrus fulvidraco.

International journal of molecular sciences

Lv WH,Chen GH,Zhuo MQ,Xu YH,Xu YC,Tan XY

Sun Dec 27 00:00:00 UTC 2020

IMPDH1/YB-1 Positive Feedback Loop Assembles Cytoophidia and Represents a Therapeutic Target in Metastatic Tumors.

Molecular therapy : the journal of the American Society of Gene Therapy

Ruan H,Song Z,Cao Q,Ni D,Xu T,Wang K,Bao L,Tong J,Xiao H,Xiao W,Cheng G,Xiong Z,Liang H,Liu D,Wang L,Olivier T,Jane BH,Yang H,Zhang X,Chen K

Wed May 06 00:00:00 UTC 2020

Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Chen Z,Li Z,Hu X,Xie F,Kuang S,Zhan B,Gao W,Chen X,Gao S,Li Y,Wang Y,Qian F,Ding C,Gan J,Ji C,Xu XW,Zhou Z,Huang J,He HH,Li J

Wed Jul 01 00:00:00 UTC 2020

LNCAROD is stabilized by m6A methylation and promotes cancer progression via forming a ternary complex with HSPA1A and YBX1 in head and neck squamous cell carcinoma.

Molecular oncology

Ban Y,Tan P,Cai J,Li J,Hu M,Zhou Y,Mei Y,Tan Y,Li X,Zeng Z,Xiong W,Li G,Li X,Yi M,Xiang B

Mon Jun 01 00:00:00 UTC 2020

Cdk5 Inhibitory Peptide Prevents Loss of Neurons and Alleviates Behavioral Changes in p25 Transgenic Mice.

Journal of Alzheimer's disease : JAD

Huang Y,Huang W,Huang Y,Song P,Zhang M,Zhang HT,Pan S,Hu Y

Fri May 07 00:00:00 UTC 2021

Identification of a novel host protein interacting with the structural protein VP2 of deformed wing virus by yeast two-hybrid screening.

Virus research

Huang S,Fei D,Ma Y,Wang C,Shi D,Liu K,Li M,Ma M

Tue Sep 01 00:00:00 UTC 2020

Identification of a novel host protein interacting with the structural protein VP2 of deformed wing virus by yeast two-hybrid screening.

Virus research

Huang S,Fei D,Ma Y,Wang C,Shi D,Liu K,Li M,Ma M

Tue Sep 01 00:00:00 UTC 2020

SUMO1 modification of methyltransferase-like 3 promotes tumor progression via regulating Snail mRNA homeostasis in hepatocellular carcinoma.

Theranostics

Xu H,Wang H,Zhao W,Fu S,Li Y,Ni W,Xin Y,Li W,Yang C,Bai Y,Zhan M,Lu L

Mon Aug 02 00:00:00 UTC 2021

Enhanced YB1/EphA2 axis signaling promotes acquired resistance to sunitinib and metastatic potential in renal cell carcinoma.

Oncogene

Ruan H,Li S,Bao L,Zhang X

Tue Sep 01 00:00:00 UTC 2020

The Wnt/β-catenin/VASP positive feedback loop drives cell proliferation and migration in breast cancer.

Oncogene

Li K,Zhang J,Tian Y,He Y,Xu X,Pan W,Gao Y,Chen F,Wei L

Sun Mar 01 00:00:00 UTC 2020

The Wnt/β-catenin/VASP positive feedback loop drives cell proliferation and migration in breast cancer.

Oncogene

Li K,Zhang J,Tian Y,He Y,Xu X,Pan W,Gao Y,Chen F,Wei L

Sun Mar 01 00:00:00 UTC 2020

MICAL2 is a novel nucleocytoplasmic shuttling protein promoting cancer invasion and growth of lung adenocarcinoma.

Cancer letters

Zhou W,Liu Y,Gao Y,Cheng Y,Chang R,Li X,Zhou Y,Wang S,Liang L,Duan C,Zhang C

Tue Jul 28 00:00:00 UTC 2020

Structural insights into the intramolecular interactions of centromere protein CENP-I.

Journal of molecular recognition : JMR

Zhang Y,Zhao C,Cao B,Ye J,Huang H,Hu L,Tian W,He X

Wed Jul 01 00:00:00 UTC 2020

Salidroside-Mediated Autophagic Targeting of Active Src and Caveolin-1 Suppresses Low-Density Lipoprotein Transcytosis across Endothelial Cells.

Oxidative medicine and cellular longevity

Bai X,Jia X,Lu Y,Zhu L,Zhao Y,Cheng W,Shu M,Jin S

Fri May 14 00:00:00 UTC 2021

Succinylation at a key residue of FEN1 is involved in the DNA damage response to maintain genome stability.

American journal of physiology. Cell physiology

Shi R,Wang Y,Gao Y,Xu X,Mao S,Xiao Y,Song S,Wang L,Tian B,Zhao Y,Hua Y,Xu H

Thu Oct 01 00:00:00 UTC 2020

Monoubiquitination of p120-catenin is essential for TGFβ-induced epithelial-mesenchymal transition and tumor metastasis.

Science advances

Wu Q,Li G,Wen C,Zeng T,Fan Y,Liu C,Fu GF,Xie C,Lin Q,Xie L,Huang L,Pu P,Ouyang Z,Chan HL,Zhao TJ,Chen XL,Fu G,Wang HR

Wed Jan 01 00:00:00 UTC 2020

Espin distribution as revealed by super-resolution microscopy of stereocilia.

American journal of translational research

Qi J,Zhang L,Tan F,Liu Y,Chu C,Zhu W,Wang Y,Qi Z,Chai R

Mon Sep 28 00:00:00 UTC 2020

Genetic code expansion in mammalian cells: A plasmid system comparison.

Bioorganic & medicinal chemistry

Zhou W,Wesalo JS,Liu J,Deiters A

Tue Dec 15 00:00:00 UTC 2020

Targeting the KIF4A/AR Axis to Reverse Endocrine Therapy Resistance in Castration-resistant Prostate Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

Cao Q,Song Z,Ruan H,Wang C,Yang X,Bao L,Wang K,Cheng G,Xu T,Xiao W,Xiong Z,Liu D,Yang M,Zhou D,Yang H,Chen K,Zhang X

Sun Mar 15 00:00:00 UTC 2020

C/EBPγ is a critical negative regulator of LPS-/IgG immune complex-induced acute lung injury through the downregulation of C/EBPβ-/C/EBPδ-dependent C/EBP transcription activation.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Yan C,Zhang L,Yang L,Zhang Q,Wang X

Thu Oct 01 00:00:00 UTC 2020

Fam83d modulates MAP kinase and AKT signaling and is induced during neurogenic skeletal muscle atrophy.

Cellular signalling

Cooper LM,Hanson A,Kavanagh JA,Waddell DS

Mon Jun 01 00:00:00 UTC 2020

Akt inhibition-dependent downregulation of the Wnt/β-Catenin Signaling pathway contributes to antimony-induced neurotoxicity.

The Science of the total environment

Shi W,Tang Y,Zhi Y,Li Z,Yu S,Jiang J,Zhu J,Li J,Wang F,Su L,Zhao X

Thu Oct 01 00:00:00 UTC 2020

Virus-induced p38 MAPK activation facilitates viral infection.

Theranostics

Cheng Y,Sun F,Wang L,Gao M,Xie Y,Sun Y,Liu H,Yuan Y,Yi W,Huang Z,Yan H,Peng K,Wu Y,Cao Z

Fri Dec 11 00:00:00 UTC 2020

Virus-induced p38 MAPK activation facilitates viral infection.

Theranostics

Cheng Y,Sun F,Wang L,Gao M,Xie Y,Sun Y,Liu H,Yuan Y,Yi W,Huang Z,Yan H,Peng K,Wu Y,Cao Z

Fri Dec 11 00:00:00 UTC 2020

Identification of the Functional Domain of HPIV3 Matrix Protein Interacting with Nucleocapsid Protein.

BioMed research international

Deng X,Zhang C,Zhang K,Lu N,He Y,Liu J,Yang Z,Zhang G

Mon Sep 13 00:00:00 UTC 2021

WDR63 inhibits Arp2/3-dependent actin polymerization and mediates the function of p53 in suppressing metastasis.

EMBO reports

Zhao K,Wang D,Zhao X,Wang C,Gao Y,Liu K,Wang F,Wu X,Wang X,Sun L,Zang J,Mei Y

Fri Apr 03 00:00:00 UTC 2020

Overexpression of Mucin 1 Suppresses the Therapeutical Efficacy of Disulfiram against Canine Mammary Tumor.

Animals : an open access journal from MDPI

Zhao Y,Lin Z,Lin Z,Zhou C,Liu G,Lin J,Zhang D,Lin D

Sun Dec 27 00:00:00 UTC 2020

A New Method for Chromosomes Preparation by ATP-Competitive Inhibitor SP600125 via Enhancement of Endomitosis in Fish.

Frontiers in bioengineering and biotechnology

Xu W,Mo Y,He Y,Fan Y,He G,Fu W,Chen S,Liu J,Liu W,Peng L,Xiao Y

Tue Feb 02 00:00:00 UTC 2021

RBM4 regulates M1 macrophages polarization through targeting STAT1-mediated glycolysis.

International immunopharmacology

Huangfu N,Zheng W,Xu Z,Wang S,Wang Y,Cheng J,Li Z,Cheng K,Zhang S,Chen X,Zhu J

Mon Jun 01 00:00:00 UTC 2020

RBM4 regulates M1 macrophages polarization through targeting STAT1-mediated glycolysis.

International immunopharmacology

Huangfu N,Zheng W,Xu Z,Wang S,Wang Y,Cheng J,Li Z,Cheng K,Zhang S,Chen X,Zhu J

Mon Jun 01 00:00:00 UTC 2020

HDAC8-dependent deacetylation of PKM2 directs nuclear localization and glycolysis to promote proliferation in hepatocellular carcinoma.

Cell death & disease

Zhang R,Shen M,Wu C,Chen Y,Lu J,Li J,Zhao L,Meng H,Zhou X,Huang G,Zhao X,Liu J

Sat Dec 05 00:00:00 UTC 2020

HDAC8-dependent deacetylation of PKM2 directs nuclear localization and glycolysis to promote proliferation in hepatocellular carcinoma.

Cell death & disease

Zhang R,Shen M,Wu C,Chen Y,Lu J,Li J,Zhao L,Meng H,Zhou X,Huang G,Zhao X,Liu J

Sat Dec 05 00:00:00 UTC 2020

DDX39B interacts with the pattern recognition receptor pathway to inhibit NF-κB and sensitize to alkylating chemotherapy.

BMC biology

Szymura SJ,Bernal GM,Wu L,Zhang Z,Crawley CD,Voce DJ,Campbell PA,Ranoa DE,Weichselbaum RR,Yamini B

Tue Mar 24 00:00:00 UTC 2020

HEATR1 deficiency promotes pancreatic cancer proliferation and gemcitabine resistance by up-regulating Nrf2 signaling.

Redox biology

Zhou Y,Wang K,Zhou Y,Li T,Yang M,Wang R,Chen Y,Cao M,Hu R

Wed Jan 01 00:00:00 UTC 2020

RXRα and MRTF-A have a synergistic effect in the retinoic acid-induced neural-like differentiation of adult bone marrow-derived mesenchymal stem cells.

Cell biology international

Luo Y,Liang C,Liu Y,Liu X,Xu Y

Mon Jun 01 00:00:00 UTC 2020

β-TrCP1 promotes cell proliferation via TNF-dependent NF-κB activation in diffuse large B cell lymphoma.

Cancer biology & therapy

Cai N,Chen Z,Huang Y,Shao S,Yu H,Wang Y,He S

Mon Jul 05 00:00:00 UTC 2021

Redox DAPK1 destabilizes Pellino1 to govern inflammation-coupling tubular damage during septic AKI.

Theranostics

Hu BC,Wu GH,Shao ZQ,Zheng Y,Liu JQ,Zhang R,Hong J,Yang XH,Sun RH,Mo SJ

Tue Jun 01 00:00:00 UTC 2021

Redox DAPK1 destabilizes Pellino1 to govern inflammation-coupling tubular damage during septic AKI.

Theranostics

Hu BC,Wu GH,Shao ZQ,Zheng Y,Liu JQ,Zhang R,Hong J,Yang XH,Sun RH,Mo SJ

Tue Jun 01 00:00:00 UTC 2021

Redox DAPK1 destabilizes Pellino1 to govern inflammation-coupling tubular damage during septic AKI.

Theranostics

Hu BC,Wu GH,Shao ZQ,Zheng Y,Liu JQ,Zhang R,Hong J,Yang XH,Sun RH,Mo SJ

Tue Jun 01 00:00:00 UTC 2021

The Capsid Protein of Semliki Forest Virus Antagonizes RNA Interference in Mammalian Cells.

Journal of virology

Qian Q,Zhou H,Shu T,Mu J,Fang Y,Xu J,Li T,Kong J,Qiu Y,Zhou X

Fri Jan 17 00:00:00 UTC 2020

Nuclear export of chimeric mRNAs depends on an lncRNA-triggered autoregulatory loop in blood malignancies.

Cell death & disease

Chen ZH,Chen TQ,Zeng ZC,Wang D,Han C,Sun YM,Huang W,Sun LY,Fang K,Chen YQ,Luo XQ,Wang WT

Thu Jul 23 00:00:00 UTC 2020

Rare mutations in the autophagy-regulating gene AMBRA1 contribute to human neural tube defects.

Human mutation

Ye J,Tong Y,Lv J,Peng R,Chen S,Kuang L,Su K,Zheng Y,Zhang T,Zhang F,Jin L,Yang X,Wang H

Sat Aug 01 00:00:00 UTC 2020

Site-specific contacts enable distinct modes of TRPV1 regulation by the potassium channel Kvβ1 subunit.

The Journal of biological chemistry

Wang Y,Mo X,Ping C,Huang Q,Zhang H,Xie C,Zhong B,Li D,Yao J

Fri Dec 11 00:00:00 UTC 2020

Site-specific contacts enable distinct modes of TRPV1 regulation by the potassium channel Kvβ1 subunit.

The Journal of biological chemistry

Wang Y,Mo X,Ping C,Huang Q,Zhang H,Xie C,Zhong B,Li D,Yao J

Fri Dec 11 00:00:00 UTC 2020

HNF1B inhibits cell proliferation via repression of SMAD6 expression in prostate cancer.

Journal of cellular and molecular medicine

Lu W,Sun J,Zhou H,Wang F,Zhao C,Li K,Fan C,Ding G,Wang J

Tue Dec 01 00:00:00 UTC 2020

Direct Proteomic Mapping of Cysteine Persulfidation.

Antioxidants & redox signaling

Fu L,Liu K,He J,Tian C,Yu X,Yang J

Fri Nov 20 00:00:00 UTC 2020

The DDX23 Negatively Regulates Translation and Replication of Foot-and-Mouth Disease Virus and Is Degraded by 3C Proteinase.

Viruses

Abdullah SW,Han S,Wu J,Zhang Y,Bai M,Jin Y,Zhi X,Guan J,Sun S,Guo H

Wed Nov 25 00:00:00 UTC 2020

Inhibitory Activity of a Scorpion Defensin BmKDfsin3 against Hepatitis C Virus.

Antibiotics (Basel, Switzerland)

Cheng Y,Sun F,Li S,Gao M,Wang L,Sarhan M,Abdel-Rahman MA,Li W,Kwok HF,Wu Y,Cao Z

Fri Jan 17 00:00:00 UTC 2020

An H3K4me3 reader, BAP18 as an adaptor of COMPASS-like core subunits co-activates ERα action and associates with the sensitivity of antiestrogen in breast cancer.

Nucleic acids research

Sun G,Wang C,Wang S,Sun H,Zeng K,Zou R,Lin L,Liu W,Sun N,Song H,Liu W,Zhou T,Jin F,Shan Z,Zhao Y

Wed Nov 04 00:00:00 UTC 2020

PKM2-c-Myc-Survivin Cascade Regulates the Cell Proliferation, Migration, and Tamoxifen Resistance in Breast Cancer.

Frontiers in pharmacology

Yu P,Li AX,Chen XS,Tian M,Wang HY,Wang XL,Zhang Y,Wang KS,Cheng Y

Tue Oct 06 00:00:00 UTC 2020

Regulation of Hippo signaling and triple negative breast cancer progression by an ubiquitin ligase RNF187.

Oncogenesis

Wang Z,Kong Q,Su P,Duan M,Xue M,Li X,Tang J,Gao Z,Wang B,Li Z,Liu Y,Yang X,Cao R,Song T,Wang K,Cai Y,Wu D,Li J,Wu G,Guled AM,Zhu J,Yan C,Zhuang T

Fri Mar 20 00:00:00 UTC 2020

Epstein-Barr Virus Early Protein BFRF1 Suppresses IFN-β Activity by Inhibiting the Activation of IRF3.

Frontiers in immunology

Wang P,Deng Y,Guo Y,Xu Z,Li Y,Ou X,Xie L,Lu M,Zhong J,Li B,Hu L,Deng S,Peng T,Cai M,Li M

Thu Apr 29 00:00:00 UTC 2021

Interaction between PHB2 and Enterovirus A71 VP1 Induces Autophagy and Affects EV-A71 Infection.

Viruses

Su W,Huang S,Zhu H,Zhang B,Wu X

Wed Apr 08 00:00:00 UTC 2020

Interaction between PHB2 and Enterovirus A71 VP1 Induces Autophagy and Affects EV-A71 Infection.

Viruses

Su W,Huang S,Zhu H,Zhang B,Wu X

Wed Apr 08 00:00:00 UTC 2020

MKL-1 is a coactivator for STAT5b, the regulator of Treg cell development and function.

Cell communication and signaling : CCS

Xiang Y,Wang J,Li JP,Guo W,Huang F,Zhang HM,Li HH,Dai ZT,Zhang ZJ,Li H,Bao LY,Gu CJ,Chen K,Zhang TC,Liao XH

Thu Jul 09 00:00:00 UTC 2020

Dual-specificity phosphatase 29 is induced during neurogenic skeletal muscle atrophy and attenuates glucocorticoid receptor activity in muscle cell culture.

American journal of physiology. Cell physiology

Cooper LM,West RC,Hayes CS,Waddell DS

Sat Aug 01 00:00:00 UTC 2020

SAS-6 Association with γ-Tubulin Ring Complex Is Required for Centriole Duplication in Human Cells.

Current biology : CB

Gupta H,Rajeev R,Sasmal R,Radhakrishnan RM,Anand U,Chandran H,Aparna NR,Agasti S,Manna TK

Mon Jun 22 00:00:00 UTC 2020

Salvia miltiorrhiza-Derived Sal-miR-58 Induces Autophagy and Attenuates Inflammation in Vascular Smooth Muscle Cells.

Molecular therapy. Nucleic acids

Qin Y,Zheng B,Yang GS,Yang HJ,Zhou J,Yang Z,Zhang XH,Zhao HY,Shi JH,Wen JK

Fri Sep 04 00:00:00 UTC 2020

Zinc finger protein 91 loss induces cardiac hypertrophy through adenosine A1 receptor down-regulation under pressure overload status.

Journal of cellular and molecular medicine

Wu X,You W,Wu Z,Ye F,Chen S

Tue Sep 01 00:00:00 UTC 2020

Comprehensive identification of signaling pathways for idiopathic pulmonary arterial hypertension.

American journal of physiology. Cell physiology

Liu B,Zhu L,Yuan P,Marsboom G,Hong Z,Liu J,Zhang P,Hu Q

Fri May 01 00:00:00 UTC 2020

Comprehensive identification of signaling pathways for idiopathic pulmonary arterial hypertension.

American journal of physiology. Cell physiology

Liu B,Zhu L,Yuan P,Marsboom G,Hong Z,Liu J,Zhang P,Hu Q

Fri May 01 00:00:00 UTC 2020

EphA2 phosphorylates NLRP3 and inhibits inflammasomes in airway epithelial cells.

EMBO reports

Zhang A,Xing J,Xia T,Zhang H,Fang M,Li S,Du Y,Li XC,Zhang Z,Zeng MS

Fri Jul 03 00:00:00 UTC 2020

DIPK2A promotes STX17- and VAMP7-mediated autophagosome-lysosome fusion by binding to VAMP7B.

Autophagy

Tian X,Zheng P,Zhou C,Wang X,Ma H,Ma W,Zhou X,Teng J,Chen J

Fri May 01 00:00:00 UTC 2020

STX2 drives colorectal cancer proliferation via upregulation of EXOSC4.

Life sciences

Wang YX,Li YZ,Zhu HF,Zhang ZY,Qian XL,He GY

Tue Dec 15 00:00:00 UTC 2020

Costunolide represses hepatic fibrosis through WW domain-containing protein 2-mediated Notch3 degradation.

British journal of pharmacology

Ge MX,Liu HT,Zhang N,Niu WX,Lu ZN,Bao YY,Huang R,Yu DK,Shao RG,He HW

Wed Jan 01 00:00:00 UTC 2020

The Rare IL22RA2 Signal Peptide Coding Variant rs28385692 Decreases Secretion of IL-22BP Isoform-1, -2 and -3 and Is Associated with Risk for Multiple Sclerosis.

Cells

Gómez-Fernández P,Lopez de Lapuente Portilla A,Astobiza I,Mena J,Urtasun A,Altmann V,Matesanz F,Otaegui D,Urcelay E,Antigüedad A,Malhotra S,Montalban X,Castillo-Triviño T,Espino-Paisán L,Aktas O,Buttmann M,Chan A,Fontaine B,Gourraud PA,Hecker M,Hoffjan S,Kubisch C,Kümpfel T,Luessi F,Zettl UK,Zipp F,Alloza I,Comabella M,Lill CM,Vandenbroeck K

Fri Jan 10 00:00:00 UTC 2020

ADNP promotes neural differentiation by modulating Wnt/β-catenin signaling.

Nature communications

Sun X,Peng X,Cao Y,Zhou Y,Sun Y

Fri Jun 12 00:00:00 UTC 2020

Autophagy Promotes Duck Tembusu Virus Replication by Suppressing p62/SQSTM1-Mediated Innate Immune Responses In Vitro.

Vaccines

Hu Z,Pan Y,Cheng A,Zhang X,Wang M,Chen S,Zhu D,Liu M,Yang Q,Wu Y,Zhao X,Huang J,Zhang S,Mao S,Ou X,Yu Y,Zhang L,Liu Y,Tian B,Pan L,Rehman MU,Yin Z,Jia R

Mon Jan 13 00:00:00 UTC 2020

The testis-specific gene 1700102P08Rik is essential for male fertility.

Molecular reproduction and development

Wu XL,Yun DM,Gao S,Liang AJ,Duan ZZ,Wang HS,Wang GS,Sun F

Sat Feb 01 00:00:00 UTC 2020

PPAR-γ Mediates Ta-VNS-Induced Angiogenesis and Subsequent Functional Recovery after Experimental Stroke in Rats.

BioMed research international

Li J,Zhang K,Zhang Q,Zhou X,Wen L,Ma J,Niu L,Li C

Thu Apr 22 00:00:00 UTC 2021

Neddylation-mediated Nedd4-2 activation regulates ubiquitination modification of renal NBCe1.

Experimental cell research

Tu J,Zhang B,Fang G,Chang W,Zhao Y

Fri May 15 00:00:00 UTC 2020

Glutathione S-transferases P1-mediated interleukin-6 in tumor-associated macrophages augments drug-resistance in MCF-7 breast cancer.

Biochemical pharmacology

Dong X,Sun R,Wang J,Yu S,Cui J,Guo Z,Pan X,Sun J,Yang J,Pan LL

Tue Dec 01 00:00:00 UTC 2020

TRIM8 inhibits breast cancer proliferation by regulating estrogen signaling.

American journal of cancer research

Tian Z,Tang J,Liao X,Gong Y,Yang Q,Wu Y,Wu G

Thu Nov 12 00:00:00 UTC 2020

TRIM8 inhibits breast cancer proliferation by regulating estrogen signaling.

American journal of cancer research

Tian Z,Tang J,Liao X,Gong Y,Yang Q,Wu Y,Wu G

Thu Nov 12 00:00:00 UTC 2020

Disruption of the ERLIN-TM6SF2-APOB complex destabilizes APOB and contributes to non-alcoholic fatty liver disease.

PLoS genetics

Li BT,Sun M,Li YF,Wang JQ,Zhou ZM,Song BL,Luo J

Sat Aug 01 00:00:00 UTC 2020

HBx mediated Increase of SIRT1 Contributes to HBV-related Hepatocellular Carcinoma Tumorigenesis.

International journal of medical sciences

Wang Q,Cheng ST,Chen J

Tue Jun 01 00:00:00 UTC 2021

FKBP9 promotes the malignant behavior of glioblastoma cells and confers resistance to endoplasmic reticulum stress inducers.

Journal of experimental & clinical cancer research : CR

Xu H,Liu P,Yan Y,Fang K,Liang D,Hou X,Zhang X,Wu S,Ma J,Wang R,Li T,Piao H,Meng S

Fri Feb 28 00:00:00 UTC 2020

Role of RBM3 in the regulation of cell proliferation in hepatocellular carcinoma.

Experimental and molecular pathology

Miao X,Zhang N

Tue Dec 01 00:00:00 UTC 2020

TRIB3 promotes hepatocellular carcinoma growth and predicts poor prognosis.

Cancer biomarkers : section A of Disease markers

Wang XJ,Li FF,Zhang YJ,Jiang M,Ren WH

Mon Jul 12 00:00:00 UTC 2021

HNF1B-mediated repression of SLUG is suppressed by EZH2 in aggressive prostate cancer.

Oncogene

Wang J,He C,Gao P,Wang S,Lv R,Zhou H,Zhou Q,Zhang K,Sun J,Fan C,Ding G,Lan F

Sat Feb 01 00:00:00 UTC 2020

MyoD1 suppresses cell migration and invasion by inhibiting FUT4 transcription in human gastric cancer cells.

Cancer gene therapy

Wu F,Qin Y,Jiang Q,Zhang J,Li F,Li Q,Wang X,Gao Y,Miao J,Guo C,Yang Y,Ni L,Liu L,Zhang S,Huang C

Sun Nov 01 00:00:00 UTC 2020

Tomatidine inhibits porcine epidemic diarrhea virus replication by targeting 3CL protease.

Veterinary research

Wang P,Bai J,Liu X,Wang M,Wang X,Jiang P

Wed Nov 11 00:00:00 UTC 2020

NEK2 induces autophagy-mediated bortezomib resistance by stabilizing Beclin-1 in multiple myeloma.

Molecular oncology

Xia J,He Y,Meng B,Chen S,Zhang J,Wu X,Zhu Y,Shen Y,Feng X,Guan Y,Kuang C,Guo J,Lei Q,Wu Y,An G,Li G,Qiu L,Zhan F,Zhou W

Wed Apr 01 00:00:00 UTC 2020

Mutual antagonism between indoleamine 2,3-dioxygenase 1 and nuclear factor E2-related factor 2 regulates the maturation status of DCs in liver fibrosis.

Free radical biology & medicine

Mo C,Xie S,Zhong W,Zeng T,Huang S,Lai Y,Deng G,Zhou C,Yan W,Chen Y,Huang S,Gao L,Lv Z

Fri Nov 20 00:00:00 UTC 2020

SUMOylation of Pdia3 exacerbates proinsulin misfolding and ER stress in pancreatic beta cells.

Journal of molecular medicine (Berlin, Germany)

Li N,Luo X,Yu Q,Yang P,Chen Z,Wang X,Jiang J,Xu J,Gong Q,Eizirik DL,Zhou Z,Zhao J,Xiong F,Zhang S,Wang CY

Tue Dec 01 00:00:00 UTC 2020

Type-2 11β-hydroxysteroid dehydrogenase promotes the metastasis of colorectal cancer via the Fgfbp1-AKT pathway.

American journal of cancer research

Chen J,Liu QM,Du PC,Ning D,Mo J,Zhu HD,Wang C,Ge QY,Cheng Q,Zhang XW,Fan YW,Liang HF,Chu L,Chen XP,Zhang BX,Jiang L

Mon Sep 28 00:00:00 UTC 2020

Immunoprecipitation and mass spectrometry define TET1 interactome during oligodendrocyte differentiation.

Cell & bioscience

Zhang M,Zhang K,Wang J,Liu Y,Liu G,Jin W,Wu S,Zhao X

Mon Sep 28 00:00:00 UTC 2020

ARF6-Rac1 signaling-mediated neurite outgrowth is potentiated by the neuronal adaptor FE65 through orchestrating ARF6 and ELMO1.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Chan WWR,Li W,Chang RCC,Lau KF

Tue Dec 01 00:00:00 UTC 2020

The casein kinase 2α promotes the occurrence polycystic ovary syndrome.

Biochemical and biophysical research communications

Yu CJ,Liu X,Zhou ZY,Chen XJ,Meng YC,Gu HC,Xu JJ,Ding GL,Liu XM,Sheng JZ,Huang HF

Mon Feb 17 00:00:00 UTC 2020

Hepatitis C Virus NS2 Protein Suppresses RNA Interference in Cells.

Virologica Sinica

Zhou H,Qian Q,Shu T,Xu J,Kong J,Mu J,Qiu Y,Zhou X

Sat Aug 01 00:00:00 UTC 2020

APC2^CDH1 negatively regulates agrin signaling by promoting the ubiquitination and proteolytic degradation of DOK7.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Chen A,Bai L,Zhong K,Shu X,Wang A,Xiao Y,Zhang K,Shen C

Tue Sep 01 00:00:00 UTC 2020

Diet and Adaptive Evolution of Alanine-Glyoxylate Aminotransferase Mitochondrial Targeting in Birds.

Molecular biology and evolution

Wang BJ,Xia JM,Wang Q,Yu JL,Song Z,Zhao H

Sun Mar 01 00:00:00 UTC 2020

lncRNA SLC7A11-AS1 Promotes Chemoresistance by Blocking SCF^β-TRCP-Mediated Degradation of NRF2 in Pancreatic Cancer.

Molecular therapy. Nucleic acids

Yang Q,Li K,Huang X,Zhao C,Mei Y,Li X,Jiao L,Yang H

Fri Mar 06 00:00:00 UTC 2020

Proteolytic Processing of Neuregulin 2.

Molecular neurobiology

Czarnek M,Bereta J

Wed Apr 01 00:00:00 UTC 2020

The Extended C-Terminal Region of Influenza C Virus Nucleoprotein Is Important for Nuclear Import and Ribonucleoprotein Activity.

Journal of virology

Tang YS,Lo CY,Mok CK,Chan PK,Shaw PC

Wed May 01 00:00:00 UTC 2019

MED28 and forkhead box M1 (FOXM1) mediate matrix metalloproteinase 2 (MMP2)-dependent cellular migration in human nonsmall cell lung cancer (NSCLC) cells.

Journal of cellular physiology

Hsieh NT,Huang CY,Li CC,Wang IC,Lee MF

Mon Jul 01 00:00:00 UTC 2019

MED28 and forkhead box M1 (FOXM1) mediate matrix metalloproteinase 2 (MMP2)-dependent cellular migration in human nonsmall cell lung cancer (NSCLC) cells.

Journal of cellular physiology

Hsieh NT,Huang CY,Li CC,Wang IC,Lee MF

Mon Jul 01 00:00:00 UTC 2019

Stabilization of PTGES by deubiquitinase USP9X promotes metastatic features of lung cancer via PGE₂ signaling.

American journal of cancer research

Wang T,Jing B,Sun B,Liao Y,Song H,Xu D,Guo W,Li K,Hu M,Liu S,Ling J,Kuang Y,Feng Y,Zhou BP,Deng J

Wed Oct 11 00:00:00 UTC 2023

Tmub1 negatively regulates liver regeneration via inhibiting STAT3 phosphorylation.

Cellular signalling

Fu H,Dong R,Zhang Y,Xu J,Liu M,Chen P

Fri Mar 01 00:00:00 UTC 2019

Tmub1 negatively regulates liver regeneration via inhibiting STAT3 phosphorylation.

Cellular signalling

Fu H,Dong R,Zhang Y,Xu J,Liu M,Chen P

Fri Mar 01 00:00:00 UTC 2019

Bartonella quintana type IV secretion effector BepE-induced selective autophagy by conjugation with K63 polyubiquitin chain.

Cellular microbiology

Wang C,Fu J,Wang M,Cai Y,Hua X,Du Y,Yang Z,Li Y,Wang Z,Sheng H,Yin N,Liu X,Koehler JE,Yuan C

Mon Apr 01 00:00:00 UTC 2019

Bartonella quintana type IV secretion effector BepE-induced selective autophagy by conjugation with K63 polyubiquitin chain.

Cellular microbiology

Wang C,Fu J,Wang M,Cai Y,Hua X,Du Y,Yang Z,Li Y,Wang Z,Sheng H,Yin N,Liu X,Koehler JE,Yuan C

Mon Apr 01 00:00:00 UTC 2019

Bartonella quintana type IV secretion effector BepE-induced selective autophagy by conjugation with K63 polyubiquitin chain.

Cellular microbiology

Wang C,Fu J,Wang M,Cai Y,Hua X,Du Y,Yang Z,Li Y,Wang Z,Sheng H,Yin N,Liu X,Koehler JE,Yuan C

Mon Apr 01 00:00:00 UTC 2019

Bartonella quintana type IV secretion effector BepE-induced selective autophagy by conjugation with K63 polyubiquitin chain.

Cellular microbiology

Wang C,Fu J,Wang M,Cai Y,Hua X,Du Y,Yang Z,Li Y,Wang Z,Sheng H,Yin N,Liu X,Koehler JE,Yuan C

Mon Apr 01 00:00:00 UTC 2019

Cardioprotection of post-ischemic moderate ROS against ischemia/reperfusion via STAT3-induced the inhibition of MCU opening.

Basic research in cardiology

Wu L,Tan JL,Chen ZY,Huang G

Wed Aug 28 00:00:00 UTC 2019

Phosphorylation of Drosophila CENP-A on serine 20 regulates protein turn-over and centromere-specific loading.

Nucleic acids research

Huang A,Kremser L,Schuler F,Wilflingseder D,Lindner H,Geley S,Lusser A

Mon Nov 18 00:00:00 UTC 2019

Dissecting the Role of DDX21 in Regulating Human Cytomegalovirus Replication.

Journal of virology

Hao H,Han T,Xuan B,Sun Y,Tang S,Yue N,Qian Z

Sun Dec 15 00:00:00 UTC 2019

Glutathione S-transferases P1 protects breast cancer cell from adriamycin-induced cell death through promoting autophagy.

Cell death and differentiation

Dong X,Yang Y,Zhou Y,Bi X,Zhao N,Zhang Z,Li L,Hang Q,Zhang R,Chen D,Cao P,Yin Z,Luo L

Tue Oct 01 00:00:00 UTC 2019

Interactome of the Autoimmune Risk Protein ANKRD55.

Frontiers in immunology

Ugidos N,Mena J,Baquero S,Alloza I,Azkargorta M,Elortza F,Vandenbroeck K

Thu Oct 29 00:00:00 UTC 2020

Interactome of the Autoimmune Risk Protein ANKRD55.

Frontiers in immunology

Ugidos N,Mena J,Baquero S,Alloza I,Azkargorta M,Elortza F,Vandenbroeck K

Thu Oct 29 00:00:00 UTC 2020

Exploring the Potential of Overexpressed OsCIPK2 Rice as a Nitrogen Utilization Efficient Crop and Analysis of Its Associated Rhizo-Compartmental Microbial Communities.

International journal of molecular sciences

Khan MU,Li P,Amjad H,Khan AQ,Arafat Y,Waqas M,Li Z,Noman A,Islam W,Wu L,Zhang Z,Lin W

Thu Jul 25 00:00:00 UTC 2019

ROS-mediated inactivation of the PI3K/AKT pathway is involved in the antigastric cancer effects of thioredoxin reductase-1 inhibitor chaetocin.

Cell death & disease

Wen C,Wang H,Wu X,He L,Zhou Q,Wang F,Chen S,Huang L,Chen J,Wang H,Ye W,Li W,Yang X,Liu H,Peng J

Thu Oct 24 00:00:00 UTC 2019

The nuclear receptor Shp regulates morphine withdrawal syndrome via modulation of Ugt2b expression in mice.

Biochemical pharmacology

Chen M,Guo L,Dong D,Yu F,Zhang T,Wu B

Fri Mar 01 00:00:00 UTC 2019

ATL3 Is a Tubular ER-Phagy Receptor for GABARAP-Mediated Selective Autophagy.

Current biology : CB

Chen Q,Xiao Y,Chai P,Zheng P,Teng J,Chen J

Mon Mar 04 00:00:00 UTC 2019

STAT3 Regulates the Type I IFN-Mediated Antiviral Response by Interfering with the Nuclear Entry of STAT1.

International journal of molecular sciences

Wang H,Yuan M,Wang S,Zhang L,Zhang R,Zou X,Wang X,Chen D,Wu Z

Mon Sep 30 00:00:00 UTC 2019

PSMB1 Negatively Regulates the Innate Antiviral Immunity by Facilitating Degradation of IKK-ε.

Viruses

Wu F,Niu Z,Zhou B,Li P,Qian F

Thu Jan 24 00:00:00 UTC 2019

Identification of rare variants in cardiac sodium channel β4-subunit gene SCN4B associated with ventricular tachycardia.

Molecular genetics and genomics : MGG

Yang Q,Xiong H,Xu C,Huang Y,Tu X,Wu G,Fu F,Wang Z,Wang L,Zhao Y,Li S,Huang Y,Wang C,Wang D,Yao Y,Wang F,Wang Y,Xue Y,Wang P,Chen Q,Pu J,Wang QK

Thu Aug 01 00:00:00 UTC 2019

Icariin promotes osteogenic differentiation by suppressing Notch signaling.

European journal of pharmacology

Xu Y,Li L,Tang Y,Yang J,Jin Y,Ma C

Sun Dec 15 00:00:00 UTC 2019

Tyrosine phosphorylation activates 6-phosphogluconate dehydrogenase and promotes tumor growth and radiation resistance.

Nature communications

Liu R,Li W,Tao B,Wang X,Yang Z,Zhang Y,Wang C,Liu R,Gao H,Liang J,Yang W

Fri Mar 01 00:00:00 UTC 2019

A PINCH-1-Smurf1 signaling axis mediates mechano-regulation of BMPR2 and stem cell differentiation.

The Journal of cell biology

Guo L,Wang R,Zhang K,Yuan J,Wang J,Wang X,Ma J,Wu C

Mon Nov 04 00:00:00 UTC 2019

The endogenous retrovirus-derived long noncoding RNA TROJAN promotes triple-negative breast cancer progression via ZMYND8 degradation.

Science advances

Jin X,Xu XE,Jiang YZ,Liu YR,Sun W,Guo YJ,Ren YX,Zuo WJ,Hu X,Huang SL,Shen HJ,Lan F,He YF,Hu GH,Di GH,He XH,Li DQ,Liu S,Yu KD,Shao ZM

Fri Mar 01 00:00:00 UTC 2019

ATXN3 promotes breast cancer metastasis by deubiquitinating KLF4.

Cancer letters

Zou H,Chen H,Zhou Z,Wan Y,Liu Z

Sat Dec 28 00:00:00 UTC 2019

In-Frame Variants in STAG3 Gene Cause Premature Ovarian Insufficiency.

Frontiers in genetics

Xiao WJ,He WB,Zhang YX,Meng LL,Lu GX,Lin G,Tan YQ,Du J

Mon Sep 28 00:00:00 UTC 2020

SIRT5-mediated SDHA desuccinylation promotes clear cell renal cell carcinoma tumorigenesis.

Free radical biology & medicine

Ma Y,Qi Y,Wang L,Zheng Z,Zhang Y,Zheng J

Mon Apr 01 00:00:00 UTC 2019

A novel oncogene TRIM63 promotes cell proliferation and migration via activating Wnt/β-catenin signaling pathway in breast cancer.

Pathology, research and practice

Li K,Pan W,Ma Y,Xu X,Gao Y,He Y,Wei L,Zhang J

Tue Oct 01 00:00:00 UTC 2019

SPSB2 inhibits hepatitis C virus replication by targeting NS5A for ubiquitination and degradation.

PloS one

Wang M,Wang Y,Liu Y,Wang H,Xin X,Li J,Hao Y,Han L,Yu F,Zheng C,Shen C

Mon Mar 02 00:00:00 UTC 2020

UHRF1 suppresses retrotransposons and cooperates with PRMT5 and PIWI proteins in male germ cells.

Nature communications

Dong J,Wang X,Cao C,Wen Y,Sakashita A,Chen S,Zhang J,Zhang Y,Zhou L,Luo M,Liu M,Liao A,Namekawa SH,Yuan S

Thu Oct 17 00:00:00 UTC 2019

A novel inhibitor of nuclear factor kappa-B kinase subunit gamma mutation identified in an incontinentia pigmenti patient with syndromic tooth agenesis.

Archives of oral biology

Sun S,Li F,Liu Y,Qu H,Wong SW,Zeng L,Yu M,Feng H,Liu H,Han D

Wed May 01 00:00:00 UTC 2019

Chicken Organic Anion-Transporting Polypeptide 1A2, a Novel Avian Hepatitis E Virus (HEV) ORF2-Interacting Protein, Is Involved in Avian HEV Infection.

Journal of virology

Li H,Fan M,Liu B,Ji P,Chen Y,Zhang B,Sun Y,Huang B,Nan Y,Sun Z,Stewart JP,Hiscox JA,Zhao Q,Zhou EM

Sat Jun 01 00:00:00 UTC 2019

Agmatinase promotes the lung adenocarcinoma tumorigenesis by activating the NO-MAPKs-PI3K/Akt pathway.

Cell death & disease

Zhu HE,Yin JY,Chen DX,He S,Chen H

Thu Nov 07 00:00:00 UTC 2019

Second messenger Ap₄A polymerizes target protein HINT1 to transduce signals in FcεRI-activated mast cells.

Nature communications

Yu J,Liu Z,Liang Y,Luo F,Zhang J,Tian C,Motzik A,Zheng M,Kang J,Zhong G,Liu C,Fang P,Guo M,Razin E,Wang J

Fri Oct 11 00:00:00 UTC 2019

CCDC84 Acetylation Oscillation Regulates Centrosome Duplication by Modulating HsSAS-6 Degradation.

Cell reports

Wang T,Zou Y,Huang N,Teng J,Chen J

Tue Nov 12 00:00:00 UTC 2019

The Interaction Mechanism Between Herpes Simplex Virus 1 Glycoprotein D and Host Antiviral Protein Viperin.

Frontiers in immunology

Li M,Liao Z,Xu Z,Zou X,Wang Y,Peng H,Li Y,Ou X,Deng Y,Guo Y,Gan W,Peng T,Chen D,Cai M

Wed Oct 28 00:00:00 UTC 2020

Engineered Lactococcus lactis Secreting IL-23 Receptor-Targeted REX Protein Blockers for Modulation of IL-23/Th17-Mediated Inflammation.

Microorganisms

Plavec TV,Kuchař M,Benko A,Lišková V,Černý J,Berlec A,Malý P

Mon May 27 00:00:00 UTC 2019

Upregulated MMP28 in Hepatocellular Carcinoma Promotes Metastasis via Notch3 Signaling and Predicts Unfavorable Prognosis.

International journal of biological sciences

Zhou J,Zheng X,Feng M,Mo Z,Shan Y,Wang Y,Jin J

Mon Feb 03 00:00:00 UTC 2020

Retractile lysyl-tRNA synthetase-AIMP2 assembly in the human multi-aminoacyl-tRNA synthetase complex.

The Journal of biological chemistry

Hei Z,Wu S,Liu Z,Wang J,Fang P

Fri Mar 29 00:00:00 UTC 2019

FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver Tumorigenesis.

Developmental cell

Ji S,Liu Q,Zhang S,Chen Q,Wang C,Zhang W,Xiao C,Li Y,Nian C,Li J,Li J,Geng J,Hong L,Xie C,He Y,Chen X,Li X,Yin ZY,You H,Lin KH,Wu Q,Yu C,Johnson RL,Wang L,Chen L,Wang F,Zhou D

Mon Feb 25 00:00:00 UTC 2019

SPOP suppresses pancreatic cancer progression by promoting the degradation of NANOG.

Cell death & disease

Tan P,Xu Y,Du Y,Wu L,Guo B,Huang S,Zhu J,Li B,Lin F,Yao L

Thu Oct 17 00:00:00 UTC 2019

Rapid depletion of ESCRT protein Vps4 underlies injury-induced autophagic impediment and Wallerian degeneration.

Science advances

Wang H,Wang X,Zhang K,Wang Q,Cao X,Wang Z,Zhang S,Li A,Liu K,Fang Y

Fri Feb 01 00:00:00 UTC 2019

m⁶A methylation controls pluripotency of porcine induced pluripotent stem cells by targeting SOCS3/JAK2/STAT3 pathway in a YTHDF1/YTHDF2-orchestrated manner.

Cell death & disease

Wu R,Liu Y,Zhao Y,Bi Z,Yao Y,Liu Q,Wang F,Wang Y,Wang X

Wed Feb 20 00:00:00 UTC 2019

Novel interactions between ERα-36 and STAT3 mediate breast cancer cell migration.

Cell communication and signaling : CCS

Xiang Y,Li JP,Guo W,Wang DQ,Yao A,Zhang HM,Huang F,Li HH,Dai ZT,Zhang ZJ,Li H,Tan Y,Chen K,Bao LY,Liao XH

Tue Aug 13 00:00:00 UTC 2019

JNK activation-mediated nuclear SIRT1 protein suppression contributes to silica nanoparticle-induced pulmonary damage via p53 acetylation and cytoplasmic localisation.

Toxicology

Zhao X,Wu Y,Li J,Li D,Jin Y,Zhu P,Liu Y,Zhuang Y,Yu S,Cao W,Wei H,Wang X,Han Y,Chen G

Mon Jul 01 00:00:00 UTC 2019

FNDC3B circular RNA promotes the migration and invasion of gastric cancer cells via the regulation of E-cadherin and CD44 expression.

Journal of cellular physiology

Hong Y,Qin H,Li Y,Zhang Y,Zhuang X,Liu L,Lu K,Li L,Deng X,Liu F,Shi S,Liu G

Fri Nov 01 00:00:00 UTC 2019

NSP2 forms viroplasms during Dendrolimus punctatus cypovirus infection.

Virology

Xu C,Wang J,Yang J,Lei C,Hu J,Sun X

Mon Jul 01 00:00:00 UTC 2019

CpG oligodeoxynucleotide-specific duck TLR21 mediates activation of NF-κB signaling pathway and plays an important role in the host defence of DPV infection.

Molecular immunology

Cheng D,Wu X,Jia R,Wang M,Chen S,Liu M,Zhu D,Zhao X,Wu Y,Yang Q,Zhang S,Zhang L,Liu Y,Yin Z,Jing B,Cheng A

Fri Feb 01 00:00:00 UTC 2019

Structural basis for the recognition of K48-linked Ub chain by proteasomal receptor Rpn13.

Cell discovery

Liu Z,Dong X,Yi HW,Yang J,Gong Z,Wang Y,Liu K,Zhang WP,Tang C

Wed Sep 30 00:00:00 UTC 2020

A technique for delineating the unfolding requirements for substrate entry into retrotranslocons during endoplasmic reticulum-associated degradation.

The Journal of biological chemistry

Shi J,Hu X,Guo Y,Wang L,Ji J,Li J,Zhang ZR

Fri Dec 27 00:00:00 UTC 2019

A thiazole-derived oridonin analogue exhibits antitumor activity by directly and allosterically inhibiting STAT3.

The Journal of biological chemistry

Shen X,Zhao L,Chen P,Gong Y,Liu D,Zhang X,Dai L,Sun Q,Lou J,Jin Z,Zhang B,Niu D,Chen C,Qi X,Jia D

Fri Nov 15 00:00:00 UTC 2019

LncRNA GABPB1-AS1 and GABPB1 regulate oxidative stress during erastin-induced ferroptosis in HepG2 hepatocellular carcinoma cells.

Scientific reports

Qi W,Li Z,Xia L,Dai J,Zhang Q,Wu C,Xu S

Thu Nov 07 00:00:00 UTC 2019

Sirtuin 7 promotes 45S pre-rRNA cleavage at site 2 and determines the processing pathway.

Journal of cell science

Sirri V,Grob A,Berthelet J,Jourdan N,Roussel P

Mon Sep 02 00:00:00 UTC 2019

A novel de novo PDE4D gene mutation identified in a Chinese patient with acrodysostosis.

Genesis (New York, N.Y. : 2000)

Zhan Y,Chen W,Feng Z,Tan C,Li M,Song Y,Zhao Z,Sheng W,Huang G

Fri Nov 01 00:00:00 UTC 2019

A novel de novo PDE4D gene mutation identified in a Chinese patient with acrodysostosis.

Genesis (New York, N.Y. : 2000)

Zhan Y,Chen W,Feng Z,Tan C,Li M,Song Y,Zhao Z,Sheng W,Huang G

Fri Nov 01 00:00:00 UTC 2019

N-terminal residues of human dyskerin are required for interactions with telomerase RNA that prevent RNA degradation.

Nucleic acids research

MacNeil DE,Lambert-Lanteigne P,Autexier C

Tue Jun 04 00:00:00 UTC 2019

A novel tumor suppressor SPINK5 targets Wnt/β-catenin signaling pathway in esophageal cancer.

Cancer medicine

Wang Q,Lv Q,Bian H,Yang L,Guo KL,Ye SS,Dong XF,Tao LL

Wed May 01 00:00:00 UTC 2019

Prothymosin α promotes STAT3 acetylation to induce cystogenesis in Pkd1-deficient mice.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Chen YC,Su YC,Shieh GS,Su BH,Su WC,Huang PH,Jiang ST,Shiau AL,Wu CL

Fri Nov 01 00:00:00 UTC 2019

The Nucleoprotein and Phosphoprotein of Peste des Petits Ruminants Virus Inhibit Interferons Signaling by Blocking the JAK-STAT Pathway.

Viruses

Li P,Zhu Z,Zhang X,Dang W,Li L,Du X,Zhang M,Wu C,Xue Q,Liu X,Zheng H,Nan Y

Mon Jul 08 00:00:00 UTC 2019

A gene-based recessive diplotype exome scan discovers FGF6, a novel hepcidin-regulating iron-metabolism gene.

Blood

Guo S,Jiang S,Epperla N,Ma Y,Maadooliat M,Ye Z,Olson B,Wang M,Kitchner T,Joyce J,An P,Wang F,Strenn R,Mazza JJ,Meece JK,Wu W,Jin L,Smith JA,Wang J,Schrodi SJ

Thu Apr 25 00:00:00 UTC 2019

MUC16 impacts tumor proliferation and migration through cytoplasmic translocation of P120-catenin in epithelial ovarian cancer cells: an original research.

BMC cancer

Chen X,Li X,Wang X,Zhu Q,Wu X,Wang X

Fri Feb 22 00:00:00 UTC 2019

Serum deprivation response functions as a tumor suppressor gene in papillary thyroid cancer.

Clinical genetics

Wang QX,Chen ED,Cai YF,Zhou YL,Dong SY,Zhang XH,Wang OC,Li Q

Fri Nov 01 00:00:00 UTC 2019

NOS1 inhibits the interferon response of cancer cells by S-nitrosylation of HDAC2.

Journal of experimental & clinical cancer research : CR

Xu P,Ye S,Li K,Huang M,Wang Q,Zeng S,Chen X,Gao W,Chen J,Zhang Q,Zhong Z,Lin Y,Rong Z,Xu Y,Hao B,Peng A,Ouyang M,Liu Q

Thu Dec 05 00:00:00 UTC 2019

Functional characterization of a novel GUCA1A missense mutation (D144G) in autosomal dominant cone dystrophy: A novel pathogenic GUCA1A variant in COD.

Molecular vision

Tang S,Xia Y,Dai Y,Liu Y,Li J,Pan X,Chen P

Fri Jul 10 00:00:00 UTC 2020

DHAV-1 Inhibits Type I Interferon Signaling to Assist Viral Adaption by Increasing the Expression of SOCS3.

Frontiers in immunology

Xie J,Wang M,Cheng A,Zhao XX,Liu M,Zhu D,Chen S,Jia R,Yang Q,Wu Y,Zhang S,Liu Y,Yu Y,Zhang L,Chen X

Wed Aug 12 00:00:00 UTC 2020

BRD4 Promotes Gastric Cancer Progression and Metastasis through Acetylation-Dependent Stabilization of Snail.

Cancer research

Qin ZY,Wang T,Su S,Shen LT,Zhu GX,Liu Q,Zhang L,Liu KW,Zhang Y,Zhou ZH,Zhang XN,Wen LZ,Yao YL,Sun WJ,Guo Y,Liu KJ,Liu L,Wang XW,Wei YL,Wang J,Xiao HL,Liu P,Bian XW,Chen DF,Wang B

Tue Oct 01 00:00:00 UTC 2019

SIRT1 downregulated FGB expression to inhibit RCC tumorigenesis by destabilizing STAT3.

Experimental cell research

Chen Y,Zhu Y,Sheng Y,Xiao J,Xiao Y,Cheng N,Chai Y,Wu X,Zhang S,Xiang T

Sun Sep 15 00:00:00 UTC 2019

Nascent Pre-rRNA Sorting via Phase Separation Drives the Assembly of Dense Fibrillar Components in the Human Nucleolus.

Molecular cell

Yao RW,Xu G,Wang Y,Shan L,Luan PF,Wang Y,Wu M,Yang LZ,Xing YH,Yang L,Chen LL

Thu Dec 05 00:00:00 UTC 2019

CHML promotes liver cancer metastasis by facilitating Rab14 recycle.

Nature communications

Chen TW,Yin FF,Yuan YM,Guan DX,Zhang E,Zhang FK,Jiang H,Ma N,Wang JJ,Ni QZ,Qiu L,Feng J,Zhang XL,Bao Y,Wang K,Cheng SQ,Wang XF,Wang X,Li JJ,Xie D

Fri Jun 07 00:00:00 UTC 2019

Angiotensin blockade attenuates diabetic nephropathy in hypogonadal adult male rats.

Canadian journal of physiology and pharmacology

Makary S,Abdo M,Hassan WA,Tawfik MK

Thu Aug 01 00:00:00 UTC 2019

CD36 inhibits β-catenin/c-myc-mediated glycolysis through ubiquitination of GPC4 to repress colorectal tumorigenesis.

Nature communications

Fang Y,Shen ZY,Zhan YZ,Feng XC,Chen KL,Li YS,Deng HJ,Pan SM,Wu DH,Ding Y

Wed Sep 04 00:00:00 UTC 2019

Dynamic Imaging of RNA in Living Cells by CRISPR-Cas13 Systems.

Molecular cell

Yang LZ,Wang Y,Li SQ,Yao RW,Luan PF,Wu H,Carmichael GG,Chen LL

Thu Dec 19 00:00:00 UTC 2019

Pharmacological Targeting of the ER-Resident Chaperones GRP94 or Cyclophilin B Induces Secretion of IL-22 Binding Protein Isoform-1 (IL-22BPi1).

International journal of molecular sciences

Gómez-Fernández P,Urtasun A,Astobiza I,Mena J,Alloza I,Vandenbroeck K

Fri May 17 00:00:00 UTC 2019

AKT-mediated phosphorylation of ATG4B impairs mitochondrial activity and enhances the Warburg effect in hepatocellular carcinoma cells.

Autophagy

Ni Z,He J,Wu Y,Hu C,Dai X,Yan X,Li B,Li X,Xiong H,Li Y,Li S,Xu L,Li Y,Lian J,He F

Thu Mar 07 00:00:00 UTC 2019

AKT-mediated phosphorylation of ATG4B impairs mitochondrial activity and enhances the Warburg effect in hepatocellular carcinoma cells.

Autophagy

Ni Z,He J,Wu Y,Hu C,Dai X,Yan X,Li B,Li X,Xiong H,Li Y,Li S,Xu L,Li Y,Lian J,He F

Thu Mar 07 00:00:00 UTC 2019

Circadian regulator NR1D2 regulates glioblastoma cell proliferation and motility.

Oncogene

Yu M,Li W,Wang Q,Wang Y,Lu F

Wed Aug 01 00:00:00 UTC 2018

Circadian regulator NR1D2 regulates glioblastoma cell proliferation and motility.

Oncogene

Yu M,Li W,Wang Q,Wang Y,Lu F

Wed Aug 01 00:00:00 UTC 2018

Epigenetic silencing of TMEM176A activates ERK signaling in human hepatocellular carcinoma.

Clinical epigenetics

Li H,Zhang M,Linghu E,Zhou F,Herman JG,Hu L,Guo M

Tue Nov 06 00:00:00 UTC 2018

Epigenetic silencing of TMEM176A activates ERK signaling in human hepatocellular carcinoma.

Clinical epigenetics

Li H,Zhang M,Linghu E,Zhou F,Herman JG,Hu L,Guo M

Tue Nov 06 00:00:00 UTC 2018

Small GTPases SAR1A and SAR1B regulate the trafficking of the cardiac sodium channel Na_v1.5.

Biochimica et biophysica acta. Molecular basis of disease

Wang Z,Yu G,Liu Y,Liu S,Aridor M,Huang Y,Hu Y,Wang L,Li S,Xiong H,Tang B,Li X,Cheng C,Chakrabarti S,Wang F,Wu Q,Karnik SS,Xu C,Chen Q,Wang QK

Thu Nov 01 00:00:00 UTC 2018

Small GTPases SAR1A and SAR1B regulate the trafficking of the cardiac sodium channel Na_v1.5.

Biochimica et biophysica acta. Molecular basis of disease

Wang Z,Yu G,Liu Y,Liu S,Aridor M,Huang Y,Hu Y,Wang L,Li S,Xiong H,Tang B,Li X,Cheng C,Chakrabarti S,Wang F,Wu Q,Karnik SS,Xu C,Chen Q,Wang QK

Thu Nov 01 00:00:00 UTC 2018

Elimination of 01/A'-A0 pre-rRNA processing by-product in human cells involves cooperative action of two nuclear exosome-associated nucleases: RRP6 and DIS3.

RNA (New York, N.Y.)

Kobyłecki K,Drążkowska K,Kuliński TM,Dziembowski A,Tomecki R

Sat Dec 01 00:00:00 UTC 2018

Elimination of 01/A'-A0 pre-rRNA processing by-product in human cells involves cooperative action of two nuclear exosome-associated nucleases: RRP6 and DIS3.

RNA (New York, N.Y.)

Kobyłecki K,Drążkowska K,Kuliński TM,Dziembowski A,Tomecki R

Sat Dec 01 00:00:00 UTC 2018

mRNA m⁶A plays opposite role in regulating UCP2 and PNPLA2 protein expression in adipocytes.

International journal of obesity (2005)

Wang X,Sun B,Jiang Q,Wu R,Cai M,Yao Y,Liu Q,Shi H,Feng J,Wang Y

Thu Nov 01 00:00:00 UTC 2018

mRNA m⁶A plays opposite role in regulating UCP2 and PNPLA2 protein expression in adipocytes.

International journal of obesity (2005)

Wang X,Sun B,Jiang Q,Wu R,Cai M,Yao Y,Liu Q,Shi H,Feng J,Wang Y

Thu Nov 01 00:00:00 UTC 2018

SUMO2 modification of Aurora B and its impact on follicular development and atresia in the mouse ovary.

International journal of molecular medicine

Cao J,Liu XM,Huang LL,Wang L,Jiao XF,Huo LJ

Fri Jun 01 00:00:00 UTC 2018

SUMO2 modification of Aurora B and its impact on follicular development and atresia in the mouse ovary.

International journal of molecular medicine

Cao J,Liu XM,Huang LL,Wang L,Jiao XF,Huo LJ

Fri Jun 01 00:00:00 UTC 2018

ABIN1 inhibits HDAC1 ubiquitination and protects it from both proteasome- and lysozyme-dependent degradation.

Journal of cellular biochemistry

Ma Y,Yuan S,Tian X,Lin S,Wei S,Hu T,Chen S,Li X,Chen S,Wu D,Wang M,Guo D

Sun Apr 01 00:00:00 UTC 2018

ABIN1 inhibits HDAC1 ubiquitination and protects it from both proteasome- and lysozyme-dependent degradation.

Journal of cellular biochemistry

Ma Y,Yuan S,Tian X,Lin S,Wei S,Hu T,Chen S,Li X,Chen S,Wu D,Wang M,Guo D

Sun Apr 01 00:00:00 UTC 2018

hnRNP A1 promotes keratinocyte cell survival post UVB radiation through PI3K/Akt/mTOR pathway.

Experimental cell research

Feng J,Liao Y,Xu X,Yi Q,He L,Tang L

Mon Jan 15 00:00:00 UTC 2018

hnRNP A1 promotes keratinocyte cell survival post UVB radiation through PI3K/Akt/mTOR pathway.

Experimental cell research

Feng J,Liao Y,Xu X,Yi Q,He L,Tang L

Mon Jan 15 00:00:00 UTC 2018

A serotonin receptor (Cg5-HTR-1) mediating immune response in oyster Crassostrea gigas.

Developmental and comparative immunology

Jia Y,Yang B,Dong W,Liu Z,Lv Z,Jia Z,Qiu L,Wang L,Song L

Tue May 01 00:00:00 UTC 2018

A serotonin receptor (Cg5-HTR-1) mediating immune response in oyster Crassostrea gigas.

Developmental and comparative immunology

Jia Y,Yang B,Dong W,Liu Z,Lv Z,Jia Z,Qiu L,Wang L,Song L

Tue May 01 00:00:00 UTC 2018

p19-Targeting ILP Protein Blockers of IL-23/Th-17 Pro-Inflammatory Axis Displayed on Engineered Bacteria of Food Origin.

International journal of molecular sciences

Škrlec K,Zadravec P,Hlavničková M,Kuchař M,Vaňková L,Petroková H,Křížová L,Černý J,Berlec A,Malý P

Sun Jul 01 00:00:00 UTC 2018

p19-Targeting ILP Protein Blockers of IL-23/Th-17 Pro-Inflammatory Axis Displayed on Engineered Bacteria of Food Origin.

International journal of molecular sciences

Škrlec K,Zadravec P,Hlavničková M,Kuchař M,Vaňková L,Petroková H,Křížová L,Černý J,Berlec A,Malý P

Sun Jul 01 00:00:00 UTC 2018

Loss of Drosha underlies dopaminergic neuron toxicity in models of Parkinson's disease.

Cell death & disease

Wang R,Lu F,Zhu G,Feng D,Nie T,Tao K,Yang S,Lei J,Huang L,Mao Z,Yang Q

Thu Jun 07 00:00:00 UTC 2018

Loss of Drosha underlies dopaminergic neuron toxicity in models of Parkinson's disease.

Cell death & disease

Wang R,Lu F,Zhu G,Feng D,Nie T,Tao K,Yang S,Lei J,Huang L,Mao Z,Yang Q

Thu Jun 07 00:00:00 UTC 2018

Three human aminoacyl-tRNA synthetases have distinct sub-mitochondrial localizations that are unaffected by disease-associated mutations.

The Journal of biological chemistry

González-Serrano LE,Karim L,Pierre F,Schwenzer H,Rötig A,Munnich A,Sissler M

Fri Aug 31 00:00:00 UTC 2018

Three human aminoacyl-tRNA synthetases have distinct sub-mitochondrial localizations that are unaffected by disease-associated mutations.

The Journal of biological chemistry

González-Serrano LE,Karim L,Pierre F,Schwenzer H,Rötig A,Munnich A,Sissler M

Fri Aug 31 00:00:00 UTC 2018

PINK1 suppresses alpha-synuclein-induced neuronal injury: a novel mechanism in protein phosphatase 2A activation.

Oncotarget

Yang W,Wang X,Liu J,Duan C,Gao G,Lu L,Yu S,Yang H

Tue Jan 02 00:00:00 UTC 2018

Long Interleukin-22 Binding Protein Isoform-1 Is an Intracellular Activator of the Unfolded Protein Response.

Frontiers in immunology

Gómez-Fernández P,Urtasun A,Paton AW,Paton JC,Borrego F,Dersh D,Argon Y,Alloza I,Vandenbroeck K

Mon Oct 21 00:00:00 UTC 2019

Long Interleukin-22 Binding Protein Isoform-1 Is an Intracellular Activator of the Unfolded Protein Response.

Frontiers in immunology

Gómez-Fernández P,Urtasun A,Paton AW,Paton JC,Borrego F,Dersh D,Argon Y,Alloza I,Vandenbroeck K

Mon Oct 21 00:00:00 UTC 2019

MiR-126 negatively regulates PLK-4 to impact the development of hepatocellular carcinoma via ATR/CHEK1 pathway.

Cell death & disease

Bao J,Yu Y,Chen J,He Y,Chen X,Ren Z,Xue C,Liu L,Hu Q,Li J,Cui G,Sun R

Fri Oct 12 00:00:00 UTC 2018

MiR-126 negatively regulates PLK-4 to impact the development of hepatocellular carcinoma via ATR/CHEK1 pathway.

Cell death & disease

Bao J,Yu Y,Chen J,He Y,Chen X,Ren Z,Xue C,Liu L,Hu Q,Li J,Cui G,Sun R

Fri Oct 12 00:00:00 UTC 2018

Imbalanced LIMK1 and LIMK2 expression leads to human colorectal cancer progression and metastasis via promoting β-catenin nuclear translocation.

Cell death & disease

Zhang Y,Li A,Shi J,Fang Y,Gu C,Cai J,Lin C,Zhao L,Liu S

Tue Jul 03 00:00:00 UTC 2018

Imbalanced LIMK1 and LIMK2 expression leads to human colorectal cancer progression and metastasis via promoting β-catenin nuclear translocation.

Cell death & disease

Zhang Y,Li A,Shi J,Fang Y,Gu C,Cai J,Lin C,Zhao L,Liu S

Tue Jul 03 00:00:00 UTC 2018

Subculturing cells have no effect on CRISPR/Cas9-mediated cleavage of UL30 gene in pseudorabies virus.

Animal models and experimental medicine

Ren LZ,Peng ZY,Ouyang T,Liu XH,Chen XR,Ye L,Fan JW,Ouyang HS,Pang DX,Bai JY

Thu Mar 01 00:00:00 UTC 2018

Upregulated IQUB promotes cell proliferation and migration via activating Akt/GSK3β/β-catenin signaling pathway in breast cancer.

Cancer medicine

Li K,Ma YB,Zhang Z,Tian YH,Xu XL,He YQ,Xu L,Gao Y,Pan WT,Song WJ,He X,Wei L

Wed Aug 01 00:00:00 UTC 2018

Upregulated IQUB promotes cell proliferation and migration via activating Akt/GSK3β/β-catenin signaling pathway in breast cancer.

Cancer medicine

Li K,Ma YB,Zhang Z,Tian YH,Xu XL,He YQ,Xu L,Gao Y,Pan WT,Song WJ,He X,Wei L

Wed Aug 01 00:00:00 UTC 2018

WDR1 Promotes Cell Growth and Migration and Contributes to Malignant Phenotypes of Non-small Cell Lung Cancer through ADF/cofilin-mediated Actin Dynamics.

International journal of biological sciences

Yuan B,Zhang R,Hu J,Liu Z,Yang C,Zhang T,Zhang C

Mon Aug 12 00:00:00 UTC 2019

WDR1 Promotes Cell Growth and Migration and Contributes to Malignant Phenotypes of Non-small Cell Lung Cancer through ADF/cofilin-mediated Actin Dynamics.

International journal of biological sciences

Yuan B,Zhang R,Hu J,Liu Z,Yang C,Zhang T,Zhang C

Mon Aug 12 00:00:00 UTC 2019

WDR1 Promotes Cell Growth and Migration and Contributes to Malignant Phenotypes of Non-small Cell Lung Cancer through ADF/cofilin-mediated Actin Dynamics.

International journal of biological sciences

Yuan B,Zhang R,Hu J,Liu Z,Yang C,Zhang T,Zhang C

Mon Aug 12 00:00:00 UTC 2019

WDR1 Promotes Cell Growth and Migration and Contributes to Malignant Phenotypes of Non-small Cell Lung Cancer through ADF/cofilin-mediated Actin Dynamics.

International journal of biological sciences

Yuan B,Zhang R,Hu J,Liu Z,Yang C,Zhang T,Zhang C

Mon Aug 12 00:00:00 UTC 2019

LINC01088 inhibits tumorigenesis of ovarian epithelial cells by targeting miR-24-1-5p.

Scientific reports

Zhang W,Fei J,Yu S,Shen J,Zhu X,Sadhukhan A,Lu W,Zhou J

Tue Feb 13 00:00:00 UTC 2018

LINC01088 inhibits tumorigenesis of ovarian epithelial cells by targeting miR-24-1-5p.

Scientific reports

Zhang W,Fei J,Yu S,Shen J,Zhu X,Sadhukhan A,Lu W,Zhou J

Tue Feb 13 00:00:00 UTC 2018

Bacterial effector NleL promotes enterohemorrhagic E. coli-induced attaching and effacing lesions by ubiquitylating and inactivating JNK.

PLoS pathogens

Sheng X,You Q,Zhu H,Chang Z,Li Q,Wang H,Wang C,Wang H,Hui L,Du C,Xie X,Zeng R,Lin A,Shi D,Ruan K,Yan J,Gao GF,Shao F,Hu R

Sat Jul 01 00:00:00 UTC 2017

Bacterial effector NleL promotes enterohemorrhagic E. coli-induced attaching and effacing lesions by ubiquitylating and inactivating JNK.

PLoS pathogens

Sheng X,You Q,Zhu H,Chang Z,Li Q,Wang H,Wang C,Wang H,Hui L,Du C,Xie X,Zeng R,Lin A,Shi D,Ruan K,Yan J,Gao GF,Shao F,Hu R

Sat Jul 01 00:00:00 UTC 2017

MicroRNA-130b transcriptionally regulated by histone H3 deacetylation renders Akt ubiquitination and apoptosis resistance to 6-OHDA.

Biochimica et biophysica acta. Molecular basis of disease

Xu L,Jia Y,Yang XH,Han F,Zheng Y,Ni Y,Chen X,Hong J,Liu JQ,Li Q,Sun RH,Mo SJ

Thu Jun 01 00:00:00 UTC 2017

MicroRNA-130b transcriptionally regulated by histone H3 deacetylation renders Akt ubiquitination and apoptosis resistance to 6-OHDA.

Biochimica et biophysica acta. Molecular basis of disease

Xu L,Jia Y,Yang XH,Han F,Zheng Y,Ni Y,Chen X,Hong J,Liu JQ,Li Q,Sun RH,Mo SJ

Thu Jun 01 00:00:00 UTC 2017

Rootletin prevents Cep68 from VHL-mediated proteasomal degradation to maintain centrosome cohesion.

Biochimica et biophysica acta. Molecular cell research

Yin H,Zheng L,Liu W,Zhang D,Li W,Yuan L

Sat Apr 01 00:00:00 UTC 2017

Rootletin prevents Cep68 from VHL-mediated proteasomal degradation to maintain centrosome cohesion.

Biochimica et biophysica acta. Molecular cell research

Yin H,Zheng L,Liu W,Zhang D,Li W,Yuan L

Sat Apr 01 00:00:00 UTC 2017

Centrosomal MCM7 strengthens the Cep68-VHL interaction and excessive MCM7 leads to centrosome splitting resulting from increase in Cep68 ubiquitination and proteasomal degradation.

Biochemical and biophysical research communications

Kong L,Yin H,Yuan L

Sat Aug 05 00:00:00 UTC 2017

Centrosomal MCM7 strengthens the Cep68-VHL interaction and excessive MCM7 leads to centrosome splitting resulting from increase in Cep68 ubiquitination and proteasomal degradation.

Biochemical and biophysical research communications

Kong L,Yin H,Yuan L

Sat Aug 05 00:00:00 UTC 2017

The Effect of SIN1 and Microtubules on Insulin Induced PKC ζ Activation.

Medical science monitor : international medical journal of experimental and clinical research

Yingying X,Caijuan W,Yenan Y,Yuqin T,Xueqin C,Zhongming W

Fri Jul 28 00:00:00 UTC 2017

The Effect of SIN1 and Microtubules on Insulin Induced PKC ζ Activation.

Medical science monitor : international medical journal of experimental and clinical research

Yingying X,Caijuan W,Yenan Y,Yuqin T,Xueqin C,Zhongming W

Fri Jul 28 00:00:00 UTC 2017

LncRNA-Six1 Encodes a Micropeptide to Activate Six1 in Cis and Is Involved in Cell Proliferation and Muscle Growth.

Frontiers in physiology

Cai B,Li Z,Ma M,Wang Z,Han P,Abdalla BA,Nie Q,Zhang X

Thu Oct 01 00:00:00 UTC 2020

LncRNA-Six1 Encodes a Micropeptide to Activate Six1 in Cis and Is Involved in Cell Proliferation and Muscle Growth.

Frontiers in physiology

Cai B,Li Z,Ma M,Wang Z,Han P,Abdalla BA,Nie Q,Zhang X

Thu Oct 01 00:00:00 UTC 2020

Nucleocapsid Interacts with NPM1 and Protects it from Proteolytic Cleavage, Enhancing Cell Survival, and is Involved in PEDV Growth.

Scientific reports

Shi D,Shi H,Sun D,Chen J,Zhang X,Wang X,Zhang J,Ji Z,Liu J,Cao L,Zhu X,Yuan J,Dong H,Wang X,Chang T,Liu Y,Feng L

Tue Jan 03 00:00:00 UTC 2017

Nucleocapsid Interacts with NPM1 and Protects it from Proteolytic Cleavage, Enhancing Cell Survival, and is Involved in PEDV Growth.

Scientific reports

Shi D,Shi H,Sun D,Chen J,Zhang X,Wang X,Zhang J,Ji Z,Liu J,Cao L,Zhu X,Yuan J,Dong H,Wang X,Chang T,Liu Y,Feng L

Tue Jan 03 00:00:00 UTC 2017

The Ubiquitin-like Protein FAT10 Stabilizes eEF1A1 Expression to Promote Tumor Proliferation in a Complex Manner.

Cancer research

Liu X,Chen L,Ge J,Yan C,Huang Z,Hu J,Wen C,Li M,Huang D,Qiu Y,Hao H,Yuan R,Lei J,Yu X,Shao J

Mon Aug 15 00:00:00 UTC 2016

The Ubiquitin-like Protein FAT10 Stabilizes eEF1A1 Expression to Promote Tumor Proliferation in a Complex Manner.

Cancer research

Liu X,Chen L,Ge J,Yan C,Huang Z,Hu J,Wen C,Li M,Huang D,Qiu Y,Hao H,Yuan R,Lei J,Yu X,Shao J

Mon Aug 15 00:00:00 UTC 2016

MicroRNA-17-92 regulates myoblast proliferation and differentiation by targeting the ENH1/Id1 signaling axis.

Cell death and differentiation

Qiu H,Liu N,Luo L,Zhong J,Tang Z,Kang K,Qu J,Peng W,Liu L,Li L,Gou D

Sat Oct 01 00:00:00 UTC 2016

MicroRNA-17-92 regulates myoblast proliferation and differentiation by targeting the ENH1/Id1 signaling axis.

Cell death and differentiation

Qiu H,Liu N,Luo L,Zhong J,Tang Z,Kang K,Qu J,Peng W,Liu L,Li L,Gou D

Sat Oct 01 00:00:00 UTC 2016

Activation of the RLR/MAVS Signaling Pathway by the L Protein of Mopeia Virus.

Journal of virology

Zhang LK,Xin QL,Zhu SL,Wan WW,Wang W,Xiao G

Tue Nov 15 00:00:00 UTC 2016

Activation of the RLR/MAVS Signaling Pathway by the L Protein of Mopeia Virus.

Journal of virology

Zhang LK,Xin QL,Zhu SL,Wan WW,Wang W,Xiao G

Tue Nov 15 00:00:00 UTC 2016

Increased expression of dermatopontin and its implications for testicular dysfunction in mice.

Molecular medicine reports

Cai J,Liu W,Hao J,Chen M,Li G

Tue Mar 01 00:00:00 UTC 2016

Increased expression of dermatopontin and its implications for testicular dysfunction in mice.

Molecular medicine reports

Cai J,Liu W,Hao J,Chen M,Li G

Tue Mar 01 00:00:00 UTC 2016

Competitive Inhibition of Lysine Acetyltransferase 2B by a Small Motif of the Adenoviral Oncoprotein E1A.

The Journal of biological chemistry

Shi S,Liu K,Chen Y,Zhang S,Lin J,Gong C,Jin Q,Yang XJ,Chen R,Ji Z,Han A

Fri Jul 01 00:00:00 UTC 2016

Competitive Inhibition of Lysine Acetyltransferase 2B by a Small Motif of the Adenoviral Oncoprotein E1A.

The Journal of biological chemistry

Shi S,Liu K,Chen Y,Zhang S,Lin J,Gong C,Jin Q,Yang XJ,Chen R,Ji Z,Han A

Fri Jul 01 00:00:00 UTC 2016

Overexpression of PRL7D1 in Leydig Cells Causes Male Reproductive Dysfunction in Mice.

International journal of molecular sciences

Liu Y,Su X,Hao J,Chen M,Liu W,Liao X,Li G

Wed Jan 13 00:00:00 UTC 2016

Overexpression of PRL7D1 in Leydig Cells Causes Male Reproductive Dysfunction in Mice.

International journal of molecular sciences

Liu Y,Su X,Hao J,Chen M,Liu W,Liao X,Li G

Wed Jan 13 00:00:00 UTC 2016

TDP-43 aggregation mirrors TDP-43 knockdown, affecting the expression levels of a common set of proteins.

Scientific reports

Prpar Mihevc S,Baralle M,Buratti E,Rogelj B

Mon Sep 26 00:00:00 UTC 2016

TDP-43 aggregation mirrors TDP-43 knockdown, affecting the expression levels of a common set of proteins.

Scientific reports

Prpar Mihevc S,Baralle M,Buratti E,Rogelj B

Mon Sep 26 00:00:00 UTC 2016

Overexpression of glyceraldehyde 3-phosphate dehydrogenase prevents neurovascular degeneration after retinal injury.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Cai R,Xue W,Liu S,Petersen RB,Huang K,Zheng L

Wed Jul 01 00:00:00 UTC 2015

Overexpression of glyceraldehyde 3-phosphate dehydrogenase prevents neurovascular degeneration after retinal injury.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Cai R,Xue W,Liu S,Petersen RB,Huang K,Zheng L

Wed Jul 01 00:00:00 UTC 2015

Overexpression of glyceraldehyde 3-phosphate dehydrogenase prevents neurovascular degeneration after retinal injury.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Cai R,Xue W,Liu S,Petersen RB,Huang K,Zheng L

Wed Jul 01 00:00:00 UTC 2015

Overexpression of glyceraldehyde 3-phosphate dehydrogenase prevents neurovascular degeneration after retinal injury.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Cai R,Xue W,Liu S,Petersen RB,Huang K,Zheng L

Wed Jul 01 00:00:00 UTC 2015

Sarco(endo)plasmic reticulum ATPase is a molecular partner of Wolfram syndrome 1 protein, which negatively regulates its expression.

Human molecular genetics

Zatyka M,Da Silva Xavier G,Bellomo EA,Leadbeater W,Astuti D,Smith J,Michelangeli F,Rutter GA,Barrett TG

Sun Feb 01 00:00:00 UTC 2015

Sarco(endo)plasmic reticulum ATPase is a molecular partner of Wolfram syndrome 1 protein, which negatively regulates its expression.

Human molecular genetics

Zatyka M,Da Silva Xavier G,Bellomo EA,Leadbeater W,Astuti D,Smith J,Michelangeli F,Rutter GA,Barrett TG

Sun Feb 01 00:00:00 UTC 2015

Oncogenic miR-17/20a Forms a Positive Feed-forward Loop with the p53 Kinase DAPK3 to Promote Tumorigenesis.

The Journal of biological chemistry

Cai Z,Cao R,Zhang K,Xue Y,Zhang C,Zhou Y,Zhou J,Sun H,Fu XD

Fri Aug 07 00:00:00 UTC 2015

STAT3 Protein Regulates Vascular Smooth Muscle Cell Phenotypic Switch by Interaction with Myocardin.

The Journal of biological chemistry

Liao XH,Wang N,Zhao DW,Zheng DL,Zheng L,Xing WJ,Ma WJ,Bao LY,Dong J,Zhang TC

Fri Aug 07 00:00:00 UTC 2015

STAT3 Protein Regulates Vascular Smooth Muscle Cell Phenotypic Switch by Interaction with Myocardin.

The Journal of biological chemistry

Liao XH,Wang N,Zhao DW,Zheng DL,Zheng L,Xing WJ,Ma WJ,Bao LY,Dong J,Zhang TC

Fri Aug 07 00:00:00 UTC 2015

STAT3 Protein Regulates Vascular Smooth Muscle Cell Phenotypic Switch by Interaction with Myocardin.

The Journal of biological chemistry

Liao XH,Wang N,Zhao DW,Zheng DL,Zheng L,Xing WJ,Ma WJ,Bao LY,Dong J,Zhang TC

Fri Aug 07 00:00:00 UTC 2015

STAT3 Protein Regulates Vascular Smooth Muscle Cell Phenotypic Switch by Interaction with Myocardin.

The Journal of biological chemistry

Liao XH,Wang N,Zhao DW,Zheng DL,Zheng L,Xing WJ,Ma WJ,Bao LY,Dong J,Zhang TC

Fri Aug 07 00:00:00 UTC 2015

Centlein mediates an interaction between C-Nap1 and Cep68 to maintain centrosome cohesion.

Journal of cell science

Fang G,Zhang D,Yin H,Zheng L,Bi X,Yuan L

Tue Apr 15 00:00:00 UTC 2014

Centlein mediates an interaction between C-Nap1 and Cep68 to maintain centrosome cohesion.

Journal of cell science

Fang G,Zhang D,Yin H,Zheng L,Bi X,Yuan L

Tue Apr 15 00:00:00 UTC 2014

Centlein mediates an interaction between C-Nap1 and Cep68 to maintain centrosome cohesion.

Journal of cell science

Fang G,Zhang D,Yin H,Zheng L,Bi X,Yuan L

Tue Apr 15 00:00:00 UTC 2014

Centlein mediates an interaction between C-Nap1 and Cep68 to maintain centrosome cohesion.

Journal of cell science

Fang G,Zhang D,Yin H,Zheng L,Bi X,Yuan L

Tue Apr 15 00:00:00 UTC 2014

Increased leaf angle1, a Raf-like MAPKKK that interacts with a nuclear protein family, regulates mechanical tissue formation in the Lamina joint of rice.

The Plant cell

Ning J,Zhang B,Wang N,Zhou Y,Xiong L

Thu Dec 01 00:00:00 UTC 2011

Increased leaf angle1, a Raf-like MAPKKK that interacts with a nuclear protein family, regulates mechanical tissue formation in the Lamina joint of rice.

The Plant cell

Ning J,Zhang B,Wang N,Zhou Y,Xiong L

Thu Dec 01 00:00:00 UTC 2011

Increased leaf angle1, a Raf-like MAPKKK that interacts with a nuclear protein family, regulates mechanical tissue formation in the Lamina joint of rice.

The Plant cell

Ning J,Zhang B,Wang N,Zhou Y,Xiong L

Thu Dec 01 00:00:00 UTC 2011

Experimental cell research

Zhou Y,Li S,Mäyränpää MI,Zhong W,Bäck N,Yan D,Olkkonen VM

Mon Nov 15 00:00:00 UTC 2010

Experimental cell research

Zhou Y,Li S,Mäyränpää MI,Zhong W,Bäck N,Yan D,Olkkonen VM

Mon Nov 15 00:00:00 UTC 2010

Experimental cell research

Zhou Y,Li S,Mäyränpää MI,Zhong W,Bäck N,Yan D,Olkkonen VM

Mon Nov 15 00:00:00 UTC 2010

Experimental cell research

Zhou Y,Li S,Mäyränpää MI,Zhong W,Bäck N,Yan D,Olkkonen VM

Mon Nov 15 00:00:00 UTC 2010

Bioinformatics

Protein Aliases: DDDDK; DDDDK epitope tag; ECS epitope tag; ECS tag; FLAG; FLAG Tag

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DDDDK Tag Polyclonal Antibody

DDDDK Tag Antibody (20543-1-AP) in ICC/IF

Product Details

20543-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Immunoprecipitation (IP)

ChIP assay (ChIP)

RNA Immunoprecipitation (RIP)

Miscellaneous PubMed (Misc)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

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